Results 11 to 20 of about 3,780 (219)

Drug Repurposing Investigation for Combating Ebola Virus Disease: Database Mining, Docking Calculations, Molecular Dynamics, and Density Functional Theory Study. [PDF]

open access: yesChemistryOpen
DrugBank database is mined to hunt prospective Ebola virus (EBOV) VP35 inhibitors utilizing docking calculations, molecular dynamics, molecular mechanics/generalized Born surface area binding energy calculations, and density functional theory computations.
Abdelrahman AHM   +5 more
europepmc   +2 more sources

Antidepressant prescribing patterns and adverse events following introduction of a National Prescribing Indicator to monitor dosulepin usage in Wales

open access: yesBritish Journal of Clinical Pharmacology, Volume 89, Issue 12, Page 3596-3605, December 2023., 2023
Aims Limiting use of the antidepressant dosulepin has been encouraged due to associated risks of toxicity. In April 2011, the All Wales Medicines Strategy Group introduced a National Prescribing Indicator (NPI) to monitor dosulepin usage. The aim of this study was to investigate antidepressant prescribing patterns, and selected adverse events in ...
Katherine Chaplin   +4 more
wiley   +1 more source

Medication clusters at hospital discharge and risk of adverse drug events at 30 days postdischarge: A population‐based cohort study of older adults

open access: yesBritish Journal of Clinical Pharmacology, Volume 89, Issue 12, Page 3715-3752, December 2023., 2023
Aims Certain combinations of medications can be harmful and may lead to serious adverse drug events (ADEs). Identifying potentially problematic medication clusters could help guide prescribing and/or deprescribing decisions in hospital. The aim of this study is to characterize medication prescribing patterns at hospital discharge and determine which ...
Daniala L. Weir   +7 more
wiley   +1 more source

Velvet bean (Mucuna pruriens): A sustainable protein source for tomorrow

open access: yesLegume Science, Volume 5, Issue 3, September 2023., 2023
Abstract Protein is one of the essential major nutrients required for the cell functioning in human body. Complete proteins, which are usually found in animal‐based proteins, despite of having high biovailability also cause adverse effect on the environment and increased the risk of diet‐related chronic diseases.
Chinju Baby   +3 more
wiley   +1 more source

Association between psychotropics use and occurrence of falls in hospitalized patients: A matched case–control study

open access: yesPsychiatry and Clinical Neurosciences Reports, Volume 2, Issue 3, September 2023., 2023
Abstract Aim Understanding the appropriate prescription of psychotropics for hospitalized patients in terms of preventing falls is an important issue. The aim of this study was to assess the associations between the occurrence of falls and the use of various individual psychotropics in hospitalized patients. Methods A retrospective matched case–control
Chihiro Morishita   +11 more
wiley   +1 more source

Anticholinergic medication use and falls in postmenopausal women: findings from the women’s health initiative cohort study [PDF]

open access: yes, 2016
Background: Results from studies assessing the association between anticholinergic use and falls are mixed, and prior studies are limited in their ability to control for important potential confounders.
Bea, JW   +7 more
core   +6 more sources

Metoclopramide Neurological Side Effects Screening; A Pharmacovigilence Study in Romanian Community Pharmacies [PDF]

open access: yes, 2015
Background. Metoclopramide is a pharmacological agent frequently used in therapy against nausea and vomiting that can occur in indigestion, motion sickness, gastric ulcer, pyloric spasm and after surgery as a side effect of some anesthetics.
Junghină, Adrian   +4 more
core   +4 more sources

Influences of the COVID‐19 pandemic on admissions and clinical outcomes in mental health disorders and self‐poisoning: Age‐ and sex‐specific analysis

open access: yesInternational Journal of Mental Health Nursing, Volume 32, Issue 4, Page 1138-1147, August 2023., 2023
Abstract We measured rates of hospital admissions for mental health disorders and self‐poisoning during the pandemic in patients without COVID‐19, compared to those admitted before the pandemic. Data were collected from 01/04/2019 to 31/03/2021, including the pandemic period from 01/03/2020.
David Fluck   +8 more
wiley   +1 more source

Prescribing patterns of antiparkinson drugs in a group of Colombian patients, 2015

open access: yesBiomédica: revista del Instituto Nacional de Salud, 2018
Introduction: Parkinson’s disease, whose prevalence in Colombia is 4.7 per 1,000 inhabitants, is a public health problem and a therapeutic challenge for health professionals. Objective: To determine the prescribing patterns of antiparkinson drugs and the
Jorge Enrique Machado-Alba   +3 more
doaj   +1 more source

Adverse events with quetiapine and clarithromycin coprescription: A population‐based retrospective cohort study

open access: yesHealth Science Reports, Volume 6, Issue 6, June 2023., 2023
Abstract Background and Aims Quetiapine is an atypical antipsychotic predominantly metabolized by the cytochrome P450 3A4 (CYP3A4) enzyme. We studied the risk of adverse events following coprescription of clarithromycin (a strong CYP3A4 inhibitor) versus azithromycin (not a CYP3A4 inhibitor) in quetiapine users.
Kevin Yau   +7 more
wiley   +1 more source

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