Results 1 to 10 of about 102,499 (199)
Antioxidant and Antiproliferative Potentials of Ficus glumosa and Its Bioactive Polyphenol Metabolites [PDF]
Pharmaceuticals, 2021 Ficus glumosa Delile (Moraceae), a reputed plant that is used in herbal medicine, is of high medicinal and nutritional value in local communities primarily ascribed to its phytochemical profile.
Moses Mutuse Mutungi +6 more
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Molecules, 2021 Allium sativum L. (garlic bulbs) and Allium fistulosum L. (Welsh onion leaves) showed quantitative differences of identified compounds: allicin and alliin (380 µg/mL and 1410 µg/mL in garlic; 20 µg/mL and 145 µg/mL in Welsh onion), and the phenolic ...
Adrian Bogdan Țigu +8 more
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Frontiers in Microbiology, 2023 The fraction of low-abundance microbiota in the marine environment is a promising target for discovering new bioactive molecules with pharmaceutical applications.
Giuliano Gattoni +13 more
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The antiproliferative potential and mechanism of action of metformin in MCF-7 cells
Future Science OA, 2023 Aim: The current study aimed to investigate the potential antiproliferative activity of metformin, the effective concentration range, and the mechanism of action.
Zhibek Bekezhankyzy +5 more
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Journal of Enzyme Inhibition and Medicinal Chemistry, 2023 A new series of piperine-carboximidamide hybrids VIa-k was developed as a new cytotoxic agent targeting EGFR, BRAF, and CDK2. The antiproliferative effect against four cancer cells was investigated against erlotinib.
Lamya H. Al-Wahaibi +4 more
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Forms and Methods for Interferon’s Encapsulation
Pharmaceutics, 2021 Interferons (IFNs) are cytokines involved in the immune response that act on innate and adaptive immunity. These proteins are natural cell-signaling glycoproteins expressed in response to viral infections, tumors, and biological inducers and constitute ...
Thelvia I. Ramos +6 more
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Antiproliferative Activity of Fucan Nanogel [PDF]
Marine Drugs, 2012 Sulfated fucans comprise families of polydisperse natural polysaccharides based on sulfated l-fucose. Our aim was to investigate whether fucan nanogel induces cell-specific responses. To that end, a non toxic fucan extracted from Spatoglossum schröederi was chemically modified by grafting hexadecylamine to the polymer hydrophilic backbone.
Nednaldo Dantas-Santos +8 more
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Novel Methylselenoesters as Antiproliferative Agents [PDF]
Molecules, 2017 Selenium (Se) compounds are potential therapeutic agents in cancer. Importantly, the biological effects of Se compounds are exerted by their metabolites, with methylselenol (CH3SeH) being one of the key executors. In this study, we developed a new series of methylselenoesters with different scaffolds aiming to modulate the release of CH3SeH.
Nuria Díaz-Argelich +5 more
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Is the Traditional Chinese Herb “Bombax Malabaricum” a Natural Anticancer Medicine?
Journal of Pharmacopuncture, 2022 Cervical spondylotic myelopathy (CSM) is common in elderly people and severe CSM patients are recommended to receive surgery. However, in some cases, surgery may fail to improve the patients’ symptoms.
Siukan Law +4 more
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Anticancer Potential of Natural Bark Products—A Review
Plants, 2021 Cell biology, plant-based extracts, structural chemistry, and laboratory in vitro or in vivo experiments are the principal aspects or interfaces that can contribute to discovering new possibilities in cancer therapy and to developing improved ...
Ema Burlacu, Corneliu Tanase
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