Results 131 to 140 of about 132,199 (306)
Antiproliferative Trihydroxyalkylcyclohexenones from Pleiogynium timoriense
, 2015 Investigation of a DCM extract of the bark of Pleiogynium timoriense from the former Merck collection of natural product extracts for antiproliferative activity indicated that it was active with an IC50 value of 1.3 μg/mL against the A2780 ovarian cancer
L. Harinantenaina Rakotondraibe (1319352) +4 more
core +1 more source
Journal of Applied Toxicology, EarlyView.ABSTRACT Selenium (Se) is an essential micronutrient that participates in redox regulation and cellular homeostasis. Selenium‐containing ionic liquids (ILsSe) have emerged as hybrid compounds combining the properties of organoselenium molecules with the tunable features of ionic liquids.
Guilherme Schmitt Rieder +17 more
wiley +1 more source
Sequence Inversion Dictates the Antiproliferative Activity of Bidirectional Tryptophan-Containing Dipeptide Libraries. [PDF]
J Pept SciReversing the peptide backbone sequence of novel tryptophyl‐dipeptides uncovers profound changes in synthetic accessibility and antineoplastic profiles against human solid tumors. Phenotypic screening identifies a conformationally restricted lead architecture that achieves sub‐micromolar growth inhibition, confirming sequence topology as a critical ...
Díaz JB +3 more
europepmc +2 more sources
Journal of Applied Toxicology, EarlyView.ABSTRACT This study highlights the potential use of Cotinus coggygria Scop. plant extract in a single‐step synthesis of biocompatible and ultrasmall AgNPs for in vitro applications. Herein, microscopic analyses revealed that AgNP exposure did not induce appreciable morphological changes in CRL‐4010 cells, whereas MCF‐7 and MDA‐MB‐231 cells exhibited ...
Ümran Ünüvar +3 more
wiley +1 more source
Sustainable ChemistryRambutan peel is a great source of bioactive compounds, the same that, over the years, has been extracted using conventional technologies which have been proven to be harmful to the environment and potentially toxic to human beings.
Christian Hernández-Hernández +7 more
doaj +1 more source
Anticancer potential of berberine: Molecular pathways and current clinical trial perspectives
JSFA reports, EarlyView.Abstract Cancer is constantly rising mortality rates due to its late prognosis, poor management, and expensive treatment. Multi‐sectoral approaches for cancer management include hygienic practices, synthetic drug exploitation, radiation therapy, and diet modifications.
Muhammad Maaz +10 more
wiley +1 more source
MoleculesIn recent years, the incidence of acute and chronic inflammatory diseases has increased significantly worldwide, intensifying the search for new therapeutic agents, especially anti-inflammatory drugs.
Renata Paprocka +5 more
doaj +1 more source
Oxadiazoles having antiproliferative activity
, 2003 Oxadiazole derivatives of general formula 1 in which X, Y, R and R2 have the meanings defined in the disclosure. The compounds have antiproliferative activity against a number of human tumors cell lines and can therefore be used for the preparation of ...
Cignarella, Giorgio +2 more
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Salt‐induced nutritional and metabolic shifts in halophytes: implications for food security
Journal of the Science of Food and Agriculture, EarlyView.Abstract Plant species vary in their response to salinity: some crops show a degree of salt tolerance, while halophytes – whether wild or cultivated – are characterized by a high capacity to thrive under saline conditions. Halophytes are considered a source of valuable secondary metabolites with potential economic value, yet they might also produce ...
Giulia Atzori +9 more
wiley +1 more source
Antiangiogenic and antiproliferative assessment of cyanobacteria
, 2014 835-842Biologically active compounds with different modes of action, such as antiproliferative, antioxidant, antimicrotubule, have been isolated from algae and cyanobacteria.
Bharat, Naveen +5 more
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