Results 171 to 180 of about 102,499 (199)

Antiproliferative potential of pinebark

2021
The anti-tumour agents from natural sources attract growing attention in recent years. Therefore, a great number of plant species have been investigated in order to identify potent biological components. Pine bark as a valuable source of bioactive polyphenols presents an attractive raw material.
Milanović, Maja, Rašković, Aleksandar, Milošević, Nataša, Četojević Simin, Dragana, Milić, Nataša   +4 more
openaire   +1 more source

Selective antiproliferative effects of thymidine

Experientia, 1993
A substance with antiproliferative bioactivity in an aqueous extract of Cordyline terminalis was purified and identified by mass spectrometry to be the natural nucleoside, thymidine. 10(-5) M Thymidine inhibited EL4 cell replication and decreased cell viability after 12-24 h. The effect was highly specific for this nucleoside.
Ooi, S.O., Sim, K.Y., Chung, M.C.M., Kon, O.L.   +3 more
openaire   +2 more sources

Antiproliferative Drugs for Restenosis Prevention

Interventional Cardiology Clinics, 2016
Cardiovascular disease is a leading cause of death and disability worldwide. Current treatment strategies aimed at treating the symptoms and consequences of obstructive vascular disease have embraced both optimal medical therapy and catheter-based percutaneous coronary intervention with drug-eluting stents.
Anwer, Habib, Aloke Virmani, Finn
openaire   +2 more sources

Antiproliferative cardenolides from Periploca graeca

Planta Medica, 2007
Nine cardiotonic steroids, six 17beta-cardenolides (2, 4, 6-9) and three 17alpha-cardenolides (1, 3, 5) have been identified from the chloroform and chloroform-methanol extracts of Periploca graeca L. (Asclepiadaceae) stems. Among these, compound 5, the 17alpha-isomer of periplocin 6, was identified as a new compound.
D. SPERA, T. SICILIANO, N. DE TOMMASI, BRACA, ALESSANDRA, A. VESSIRES   +4 more
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Triaryl Methane Derivatives as Antiproliferative Agents.

ChemInform, 2004
AbstractFor Abstract see ChemInform Abstract in Full Text.
Raed A, Al-Qawasmeh, Yoon, Lee, Ming Yu, Cao, Xiaoping, Gu, Aikaterini, Vassilakos, Jim A, Wright, Aiping, Young   +6 more
openaire   +2 more sources

Antiproliferative Action of Vitamin D

2002
During the past few years, it has become apparent that vitamin D may play an important role in malignant transformation. Epidemiological studies suggest that low vitamin D serum concentration increases especially the risk of hormone-related cancers.
Timo, Ylikomi, Ilkka, Laaksi, Yan-Ru, Lou, Paula, Martikainen, Susanna, Miettinen, Pasi, Pennanen, Sami, Purmonen, Heimo, Syvälä, Annika, Vienonen, Pentti, Tuohimaa   +9 more
openaire   +2 more sources

Total Synthesis of Antiproliferative Parvifloron F

Organic Letters, 2018
The first total synthesis of parvifloron F, a bioactive highly oxidized abietane diterpene, was achieved. The abietane skeleton was constructed by Lewis acid promoted cyclization. Preliminary structure-activity relationship correlations were established for the synthetic intermediates against human tumor cell lines.
Yohei Saito, Masuo Goto, Kyoko Nakagawa-Goto   +2 more
openaire   +2 more sources

Antiproliferative steroidal glycosides from Digitalis ciliata

Fitoterapia, 2012
Two new compounds, a furostanol glycoside (1) and a pregnane glycoside (4), along with eight known compounds, belonging to the classes of spirostane (2,3), pregnane (5-7) and cardenolide (8-10) glycosides, were isolated from the seeds of Digitalis ciliata. Their structures were elucidated by 1D and 2D-NMR experiments as well as ESI-MS analysis. For the
PERRONE, ANGELA, CAPASSO, Anna, FESTA, MICHELA, E. Kemertelidze, PIZZA, Cosimo, A. Skhirtladze, PIACENTE, Sonia   +6 more
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Antiproliferative and Cytotoxic Activities

2018
Cancer is a genetic disease, affecting many people worldwide. Chemotherapy is routinely used for cancer treatment. However, this therapeutic approach is not always effective due to the development of cell resistance and toxic effects. Plants are a reservoir of natural chemicals with chemoprotective potential against cancer and with low adverse effects.
Anesini, Claudia Alejandra, Alonso, Maria del Rosario, Martino, Renzo Fabricio   +2 more
openaire   +2 more sources

An antiproliferative bioassay for interleukin-4

Journal of Immunological Methods, 1996
Interleukin-4 (IL-4) is currently being used for therapeutic intervention in a wide range of malignant diseases as an antitumour agent. Although bioassays have been developed that measure the proliferative capacity of IL-4, none measure the antiproliferative activity of this molecule.
L A, Page, M S, Topp, R, Thorpe, A R, Mire-Sluis   +3 more
openaire   +2 more sources