Results 11 to 20 of about 102,499 (199)

A QSAR Study on the 4-Substituted Coumarins as Potent Tubulin Polymerization Inhibitors [PDF]

Advanced Pharmaceutical Bulletin, 2020
Purpose: Despite the discovery and synthesis of several anticancer drugs, cancer is still a major life threatening incident for human beings after cardiovascular diseases.
Leila Dinparast, Siavoush Dastmalchi
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(−)-6-epi-Artemisinin, a Natural Stereoisomer of (+)-Artemisinin in the Opposite Enantiomeric Series, from the Endemic Madagascar Plant Saldinia proboscidea, an Atypical Source

Molecules, 2021
Chemical and biological investigation of the Madagascar endemic plant Saldinia proboscidea led to the isolation of an isomer of artemisinin, (−)-6-epi-artemisinin (2). Its structure was elucidated using a combination of NMR and mass spectrometry.
Saholinirina Randrianarivo, Claudine Rasolohery, Sitraka Rafanomezantsoa, Heriniaina Randriamampionona, Liti Haramaty, Roger Marie Rafanomezantsoa, Eric H. Andrianasolo   +6 more
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Antiproliferative Effect of Indole Phytoalexins [PDF]

Molecules, 2016
Indole phytoalexins from crucifers have been shown to exhibit significant anti-cancer, chemopreventive, and antiproliferative activity. Phytoalexins are natural low molecular antimicrobial compounds that are synthesized and accumulated in plants after their exposure to pathogenic microorganisms. Most interestingly, crucifers appear to be the only plant
Martina Chripkova, Frantisek Zigo, Jan Mojzis   +2 more
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UJI SITOTOKSITAS DAN ANTIPROLIFERATIF SEL KANKER PAYUDARA T47D DAN SEL VERO BIJI Nigella sativa, L.

Pharmaciana, 2012
Black cumin seeds contain oil classes atisiri, terpenes, and alkaloids that can be used for traditional medicine as anticancer. The purpose of this study was to assess the cytotoxic effects of ether extract, ethanol, and infusa seed Nigella sativa, L ...
Laela Hayu Nurani
doaj   +1 more source

Antibacterial, Antiradical and Antiproliferative Potential of Green, Roasted, and Spent Coffee Extracts

Applied Sciences, 2022
The phytochemical compositions of green coffee beans (GB), roasted coffee (RC), and the solid residue known as spent coffee grounds (SCG) have been associated with beneficial physiological effects.
Gema C. Díaz-Hernández, Patricia Alvarez-Fitz, Yanik I. Maldonado-Astudillo, Javier Jiménez-Hernández, Isela Parra-Rojas, Eugenia Flores-Alfaro, Ricardo Salazar, Mónica Ramírez   +7 more
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Synthesis of Hydantoin Androgen Receptor Antagonists and Study on Their Antagonistic Activity

Molecules, 2022
Hydroxymethylthiohydantoin, hydroxymethylthiohydantoin, and hydantoin, containing a pyridine group, were synthesized to study their androgen receptor antagonistic activities.
Longjun Ma, Yan Zhou, Dehua Yang, Ming-Wei Wang, Wei Lu, Jiyu Jin   +5 more
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Antiproliferative Trihydroxyalkylcyclohexenones from Pleiogynium timoriense [PDF]

Journal of Natural Products, 2015
Investigation of a DCM extract of the bark of Pleiogynium timoriense from the former Merck collection of natural product extracts for antiproliferative activity indicated that it was active with an IC50 value of 1.3 μg/mL against the A2780 ovarian cancer cell line.
Eaton, A. L., Rakotondraibe, L. Harinantenaina, Brodie, P. J., Goetz, M., Kingston, David G. I.   +4 more
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Benzothiazole Derivatives Endowed with Antiproliferative Activity in Paraganglioma and Pancreatic Cancer Cells: Structure–Activity Relationship Studies and Target Prediction Analysis

Pharmaceuticals, 2022
The antiproliferative effects played by benzothiazoles in different cancers have aroused the interest for these molecules as promising antitumor agents.
Rosa Amoroso, Laura De Lellis, Rosalba Florio, Nazaret Moreno, Mariangela Agamennone, Barbara De Filippis, Letizia Giampietro, Cristina Maccallini, Inmaculada Fernández, Rocío Recio, Alessandro Cama, Marialuigia Fantacuzzi, Alessandra Ammazzalorso   +12 more
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Masked Phenolic-Selenium Conjugates: Potent and Selective Antiproliferative Agents Overcoming P-gp Resistance

Pharmaceuticals, 2020
Cancer accounts for one of the most complex diseases nowadays due to its multifactorial nature. Despite the vast number of cytotoxic agents developed so far, good therapeutic approaches are not always reached.
Paloma Begines, Lucía Sevilla-Horrillo, Adrián Puerta, Rebecca Puckett, Samuel Bayort, Irene Lagunes, Inés Maya, José M. Padrón, Óscar López, José G. Fernández-Bolaños   +9 more
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Flavonoids from Selaginella doederleinii Hieron and Their Antioxidant and Antiproliferative Activities

Antioxidants, 2022
Selaginella doederleinii Hieron. (S. doederleinii) is a traditional herb that is widely used in China to treat several ailments, but mainly cancer. Studies have been carried out to determine the phytochemicals ascribed to its pharmacological activity ...
Felix Wambua Muema, Ye Liu, Yongli Zhang, Guilin Chen, Mingquan Guo   +4 more
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