Results 31 to 40 of about 162,577 (262)

Antiproliferative prostaglandins activate heat shock transcription factor. [PDF]

Proceedings of the National Academy of Sciences, 1992
Treatment of human K562 erythroleukemia cells with the antiproliferative prostaglandin A1 results in the elevated transcription of two heat shock genes, HSP70 and HSP90. Parallel with increased heat shock gene transcription is the activation of heat shock transcription factor.
AMICI, CARLA, Sistonen, L, SANTORO, MARIA GABRIELLA, Morimoto, R.   +3 more
openaire   +3 more sources

Gallic Acid Content and an Antioxidant Mechanism Are Responsible for the Antiproliferative Activity of ‘Ataulfo’ Mango Peel on LS180 Cells

Molecules, 2018
Mango “Ataulfo” peel is a rich source of polyphenols (PP), with antioxidant and anti-cancer properties; however, it is unknown whether such antiproliferative activity is related to PP’s antioxidant activity.
Gustavo. R. Velderrain-Rodríguez, Heriberto Torres-Moreno, Mónica A. Villegas-Ochoa, J. Fernando Ayala-Zavala, Ramón E. Robles-Zepeda, Abraham Wall-Medrano, Gustavo A. González-Aguilar   +6 more
doaj   +1 more source

The contribution of different polyphenol compositions from chokeberry produced in China to cellular antioxidant and antiproliferative activities

Food Science and Human Wellness, 2023
Abundant polyphenols make chokeberry have beneficial antioxidant and antiproliferative activity. In order to explore the contribution of different polyphenols in chokeberry to these activities, this study was conducted to determine polyphenol composition
Ningxuan Gao, Xu Si, Wenzhong Han, Ersheng Gong, Chi Shu, Jinlong Tian, Yuehua Wang, Jiyue Zhang, Binxu Li, Bin Li   +9 more
doaj   +1 more source

Copper Ion Attenuated the Antiproliferative Activity of Di-2-pyridylhydrazone Dithiocarbamate Derivative; However, There Was a Lack of Correlation between ROS Generation and Antiproliferative Activity

Molecules, 2016
The use of chelators for cancer treatment has been an alternative option. Dithiocarbamates have recently attracted considerable attention owning to their diverse biological activities; thus, the preparation of new dithiocarbamate derivatives with ...
Tingting Wang, Yun Fu, Tengfei Huang, Youxun Liu, Meihao Wu, Yanbin Yuan, Shaoshan Li, Changzheng Li   +7 more
doaj   +1 more source

A selective alpha1D-adrenoreceptor antagonist inhibits human prostate cancer cell proliferation and motility "in vitro" [PDF]

, 2016
The progression of prostate cancer (PC) to a metastatic hormone refractory disease is the major contributor to the overall cancer mortality in men, mainly because the conventional therapies are generally ineffective at this stage. Thus, other therapeutic
Bolchi, Cristiano, Castelnovo, Luca, Colciago, Alessandra, FERRI, NICOLA, Fumagalli, Laura, Mornati, Ornella, Negri Cesi, Paola, Pallavicini, Marco, Valoti, Ermanno   +8 more
core   +2 more sources

Antiproliferative Effect of Methanolic Extract of Linum arboreum on A549 Cells

Proceedings, 2017
Many anticancer drugs in clinical use are natural product derived from natural sources. Today, investigations of anti cancer effect of different natural products are increase.
Ozgur Vatan, Ozer Yılmaz, Huzeyfe Huriyet, Tolga Cavas, Nilufer Cinkılıç   +4 more
doaj   +1 more source

Chemical investigation of a biologically active schinus molle L. leaf extract [PDF]

, 2019
The pepper tree Schinus molle L. is an evergreen ornamental plant belonging to the Anacardiaceae family, native to South America and widespread throughout the world. It has biological activities and is used in folk medicine. This paper aims to contribute
Garzoli, S., Masci, V. L., Ovidi, E., Tiezzi, A., Turchetti, G., Zago, D.   +5 more
core   +1 more source

IGF-I influences everolimus activity in medullary thyroid carcinoma [PDF]

, 2015
Context: Medullary thyroid carcinoma (MTC) is a rare tumor originating from thyroid parafollicular C cells. It has been previously demonstrated that insulin-like growth factor I (IGF-I) protects MTC from the effects of antiproliferative drugs. Everolimus,
degli Uberti, Ettore C., Di Pasquale, Carmelina, Gagliano, Teresa, GENTILIN, ERICA, MERANTE BOSCHIN, ISABELLA, Pelizzo, Mariarosa, Rossi, Martina, Rossi, Roberta, Tagliati, Federico, Zatelli, Maria Chiara   +9 more
core   +1 more source

Antioxidant and antiproliferative activity of Asparagopsis Taxiformis

Pharmacognosy Research, 2017
Asparagopsis taxiformis (Rhodophyta) is a species of red algae belonging to the family Bonnemaisoniaceae. The objective of the present study was to evaluate antioxidant and antiproliferative activity of four fractions (petroleum ether, chloroform, ethyl acetate, and methanol) of A. taxiformis.The red seaweed, A.
Neethu, P. V., Suthindhiran, K., Jayasri, M. A.   +2 more
openaire   +3 more sources

The novel mTOR inhibitor RAD001 (Everolimus) induces antiproliferative effects in human pancreatic neuroendocrine tumor cells [PDF]

, 2007
Background/Aim: Tumors exhibiting constitutively activated PI(3) K/Akt/mTOR signaling are hypersensitive to mTOR inhibitors such as RAD001 (everolimus) which is presently being investigated in clinical phase II trials in various tumor entities, including
Albert JM, Auernhammer CJ, Boulay A, Boulay A, Bousquet C, Burkhard Göke, Cao C, Christoph J. Auernhammer, Enrico N. De Toni, Faivre S, Gerald Spöttl, Grewe M, Heinrich H.D. Meyer, Hosoi H, Jeng YJ, Jennifer Meinecke, Kathrin Zitzmann, Kawamata S, Kirchner GI, Luo J, O?Reilly KE, Oberg K, Ramage JK, Sawyers CL, Shah T, Shaw RJ, Stephan Brand, Sun SY, Vignot S, von Wichert G, Wang L, Wanner K, Wendel HG, Wullschleger S, Yao JC, Yee KW   +35 more
core   +1 more source