On a heuristic point of view concerning the expression of numerous genes during the cell cycle [PDF]
, 2012 The current model of the eukaryotic cell cycle proposes that numerous genes are expressed at different times during the cell cycle. The existence of myriad control points for gene expression leads to theoretical and logical problems for cell cycle ...
Breeden +50 more
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The lumbrical muscle: a novel in situ system to evaluate adult skeletal muscle proteolysis and anticatabolic drugs for therapeutic purposes [PDF]
, 2011 Bergantin LB, Figueiredo LB, Godinho RO. the lumbrical muscle: a novel in situ system to evaluate adult skeletal muscle proteolysis and anticatabolic drugs for therapeutic purposes. J Appl Physiol 111: 1710-1718, 2011. First published September 15, 2011;
Fulks RM +7 more
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Kempopeptin C, a Novel Marine-Derived Serine Protease Inhibitor Targeting Invasive Breast Cancer
Marine Drugs, 2017 Kempopeptin C, a novel chlorinated analogue of kempopeptin B, was discovered from a marine cyanobacterium collected from Kemp Channel in Florida. The structure was elucidated using NMR spectroscopy and mass spectrometry (MS).
Fatma H. Al-Awadhi +4 more
doaj +1 more source
Bone Morphogenetic Protein (BMP)-4 and BMP-7 regulate differentially Transforming Growth Factor (TGF)-β1 in normal human lung fibroblasts (NHLF) [PDF]
, 2010 Background Airway remodelling is thought to be under the control of a complex group of molecules belonging to the Transforming Growth Factor (TGF)-superfamily.
Campbell Gaynor A +3 more
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Hepatology Research, Volume 55, Issue 7, Page 1075-1092, July 2025.Overview of the exome‐based genotype‐first reverse phenotyping approach targeting SERPINA1. The schematic illustrates key pathways, including cytolysis, cholestasis, and liver synthesis, alongside clinical and biological phenotyping through data extraction and an exome‐wide association approach.
Maël Silva Rodriguez +11 more
wiley +1 more source
What’s the importance of peptidases in cancer? [PDF]
Einstein (São Paulo), 2009 A synonym for a successful tumor spread is a productive invasive cell migration, a process by which the extracellular matrix plays the role of substrate for cells to move and reach a secondary site.
Adriana Miti Nakahata +2 more
doaj
Effect of ivermectin on the liver of gilthead seabream Sparus aurata: a proteomic approach [PDF]
, 1998 23 p., 2 tablas, 4 figuras y bibliografíaGilthead sea bream Sparus aurata is the most commercialized Mediterranean aquacultured fish species.
Varó, Inmaculada +7 more
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8.5 INCREASED ARTERIAL STIFFNESS IN PATIENTS WITH ALPHA 1 ANTITRYPSIN DEFICIENCY
Artery Research, 2009 Rationale: Alpha 1 Antitrypsin (AAT) deficiency is a familial cause of emphysema, due to reduced antiproteolytic activity within lungs. Systemic manifestations however, remain little explored. We have previously demonstrated increased arterial stiffness (
J.M. Duckers +5 more
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Unraveling the cytotoxic potential of Temozolomide loaded into PLGA nanoparticles [PDF]
, 2014 BACKGROUND: Nanotechnology has received great attention since a decade for the treatment of different varieties of cancer. However, there is a limited data available on the cytotoxic potential of Temozolomide (TMZ) formulations.
Amrita N Bajaj +6 more
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Journal of Cachexia, Sarcopenia and Muscle, Volume 16, Issue 2, April 2025.ABSTRACT Background G protein–coupled receptor 40 (GPR40) acts as a modulator of various physiological functions, including glycaemic lowering, anti‐inflammation and antioxidative stress, in several tissues. However, the role of GPR40 in skeletal muscles remains unclear.
Joo Won Kim +9 more
wiley +1 more source