Results 101 to 110 of about 17,418 (254)

Evaluation of antiprotozoal activity by Tetrahymena pyriformis [PDF]

, 2009
74 ABSTRACT Title of thesis Evaluation of antiprotozoal activity by Tetrahymena pyriformis Charles University in Prague Faculty of Pharmacy in Hradec Kralove Department of Pharmaceutical Botany and Ecology Candidate: Daniela Osecká Consultant: Mgr. Jitka
Osecká, Daniela
core  

Selective Antiprotozoal Activity of Some Strychnos Alkaloids

, 1994
peer reviewedThe in vitro activities of 28 Strychnos alkaloids have been determined against three species of protozoa and the most active compounds were then assessed for in vitro cytotoxic activity against KB cells.
Zhenping Chen, Cai, Ya, Colin W. Wright, Monique Tits, J. David Phillipson, Wright, Colin, Angenot, Luc, Kirby, Geoffrey, David Allen, Geoffrey C. Kirby, Luc Angenot, Ya Cai, Chen, Zhenping, Tits, Monique, Phillipson, J., Allen, David, Warhurst, David, David C. Warhurst   +17 more
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Goniothalamin as a Styryl‐Lactone Toxicophore in Cancer Models: Electrophile‐Driven DNA Damage, Reactive Oxygen Species–Endoplasmic Reticulum Stress Signaling and Detoxification‐Relevant Safety Considerations

Journal of Biochemical and Molecular Toxicology, Volume 40, Issue 8, August 2026.
Goniothalamin (GTN) exerts anticancer effects by promoting reactive oxygen species (ROS) generation, glutathione (GSH) depletion, DNA damage, endoplasmic reticulum (ER) stress, and mitochondrial dysfunction. These interconnected events trigger apoptosis, necroptosis, anoikis, and autophagy, while modulating mitogen‐activated protein kinase (MAPK ...
Nataša Joković, Strahinja Pešić, Marija Novaković, Anđela Dubroja Krstić, William N. Setzer, Javad Sharifi‐Rad, Daniela Calina   +6 more
wiley   +1 more source

The Mediterranean Red Alga Asparagopsis: A Source of Compounds against Leishmania

Marine Drugs, 2009
Crude extracts and column fractions from the red algae Asparagopsis taxiformis and A. armata from the Strait of Messina (Italy) were screened for the production of antimicrobial compounds.
Marina Morabito, Mark T. Hamann, Laura Tedone, Giuseppa Genovese   +3 more
doaj   +1 more source

Synthesis, Electrochemistry, In Vitro Antiprotozoal Efficacy and Mechanistic Study of Novel ‘Ferrantoin’ and Related Derivatives

Applied Organometallic Chemistry, Volume 40, Issue 7, July 2026.
1,2‐Disubstituted ferrocene analogues bearing hydantoin or rhodanine synthons were synthesised and assessed for antitrypanosomatid activity. An antileishmanial early lead, analogue 23, acting through ROS generation and hence oxidative stress, was uncovered.
Maryna Saayman, Janine Aucamp, Helena D. Janse van Rensburg, Christina Kannigadu, Rotondwa Mphephu, Andrew J. Swarts, Keisuke Suganuma, David D. N'Da   +7 more
wiley   +1 more source

Chemical Constituents and Pharmacology properties of Aristolochia triangularis: a south brazilian highly-consumed botanical with multiple bioactivities

Anais da Academia Brasileira de Ciências
: Aristolochia triangularis Cham., is one of the most frequently used medicinal plant in Southern Brazil. Preparations containing the leaves and/or stems are traditionally used as anti-inflammatory, diuretic, as well as antidote against snakebites.
SIMONE Q. OLIVEIRA, JADEL M. KRATZ, VITOR C. CHAVES, TATIANA R. GUIMARÃES, DANIELLE T.M. COSTA, SAPFO DIMITRAKOUDI, ARGYRO VONTZALIDOU, SÉRGIO A.L. BORDIGNON, CESAR P. SIMIONATO, MÁRIO STEINDEL, FLÁVIO H. REGINATTO, CLÁUDIA M.O. SIMÕES, ELOIR P. SCHENKEL   +12 more
doaj   +1 more source

Recent Advancement in the Search of Innovative Antiprotozoal Agents Targeting Trypanothione Metabolism

ChemMedChem, 2020
Leishmania and Trypanosoma parasites are responsible for the challenging neglected tropical diseases leishmaniases, Chagas disease, and human African trypanosomiasis, which account for up to 40,000 deaths annually mainly in developing countries.
Francesco Saccoliti, R. Di Santo, R. Costi   +2 more
semanticscholar   +1 more source

Antiprotozoal alkaloids from Galanthus trojanus

, 2011
Two new alkaloid N-oxides, 1-O-acetyldihydromethylpseudolycorine N-oxide, and 11-hydroxyvittatine N-oxide, ten known alkaloids; arolycoricidine, haemanthamine, O-methylnorbelladine, narcidine, dihydrolycorine, 8-O-demethylmaritidine, stylopine and ...
Somer, Nehir Unver, Carles Codina, Viladomat, Francesc, Sarikaya, Buket, Onur, Mustafa Ali, Kaya, Gulen Irem, Jaume Bastida, Onur, M. A., Kaiser, Marcel, Lauinger, Ina L., Viladomat, F., Tasdemir, D., Bastida, Jaume, Tasdemir, Deniz, Marcel Kaiser, Kaya, G. I., Sarikaya, B., Buket Sarıkaya, Deniz Tasdemir, Codina, C., Kaiser, M., Bastida, J., Lauinger, I. L., Mustafa Ali Onur, Francesc Viladomat, Codina, Carles, Gulen Irem Kaya, Ina L. Lauinger, Somer, N. U., Nehir Unver Somer   +29 more
core   +1 more source

A Short and Improved Synthesis of the Antiprotozoal Abietane Diterpenoid (–)-Sugikurojin A [PDF]

, 2016
An efficient and straightforward semisynthesis of the antiprotozoal abietane diterpenoid (–)-sugikurojin A, starting from the readily available methyl ester of callitrisic acid (4-epi-dehydroabietic acid­) isolated from sandarac resin, is reported.
González-Cardenete, Miguel A, Zaragozá, Ramón José, Zaragoza, Ramon J., González-Cardenete, Miguel A.   +3 more
core   +1 more source

Antiprotozoal Activity of Turkish Origanum onites Essential Oil and Its Components

Molecules, 2019
Essential oil of Origanum species is well known for antimicrobial activity, but only a few have been evaluated in narrow spectrum antiprotozoal assays. Herein, we assessed the antiprotozoal potential of Turkish Origanum onites L.
D. Taşdemir, M. Kaiser, B. Demirci, Fatih Demirci, K. Baser   +4 more
semanticscholar   +1 more source