Results 11 to 20 of about 7,779 (200)

Towards broadspectrum antiprotozoal agents

ARKIVOC, 2003
Since the market for antiparasitic drugs is in poor Third World countries, innovative and cost effective approaches to antiparasite drug discovery and development are urgently needed. Development of broadspectrum antiprotozoal agents acting against multiple protozoan parasites offers numerous advantages in addressing the challenges inherent in the ...
Kelly Chibale
doaj   +4 more sources

Exploring Synthetic Dihydrobenzofuran and Benzofuran Neolignans as Antiprotozoal Agents against Trypanosoma cruzi [PDF]

Pharmaceutics, 2023
Chagas disease is a neglected tropical disease that affects more than 8 million people. Although there are therapies against this disease, the search for new drugs is important because the current treatments show limited effectiveness and high toxicity ...
Mariana C. Pagotti, Herbert J. Dias, Ana Carolina B. B. Candido, Thaís A. S. Oliveira, Alexandre Borges, Nicoli D. Oliveira, Carla D. Lopes, Renato P. Orenha, Renato L. T. Parreira, Antônio E. M. Crotti, Lizandra G. Magalhães   +10 more
doaj   +2 more sources

Flavonoids from Piper Species as Promising Antiprotozoal Agents against Giardia intestinalis. Structure-Activity Relationship and Drug-Likeness Studies. [PDF]

Pharmaceuticals (Basel), 2022
Ticona JC, Bilbao-Ramos P, Amesty Á, Flores N, Dea-Ayuela MA, Bazzocchi IL, Jiménez IA.   +6 more
europepmc   +3 more sources

Volatile Compounds as Upcoming Antigiardial Agents: In Vitro Action of Carvacrol, Thymol and p-Cymene on Giardia lamblia Trophozoites [PDF]

Pharmaceutics
Background/Objectives: Carvacrol and thymol are monoterpenes present in phenolic-rich essential oils extracted from aromatic plants that exhibit antimicrobial activity.
Marisa Machado, Ana Silva, Rui Linhares, Carlos Cavaleiro, Maria C. Sousa   +4 more
doaj   +2 more sources

Quinolines: the role of substitution site in antileishmanial activity [PDF]

Frontiers in Chemistry
Leishmaniasis is one of the most widespread parasitic diseases in the world, primarily affecting the poorest and most vulnerable populations. The development of new therapeutic agents that are more efficient, safe, and selective remains a challenge.
Orlando G. Elso, Guadalupe García Liñares   +1 more
doaj   +2 more sources

A Divergent Synthesis of Numerous Pyrroloiminoquinone Alkaloids Identifies Promising Antiprotozoal Agents. [PDF]

J Am Chem Soc
Barnes GL, Magann NL, Perrotta D, Hörmann FM, Fernandez S, Vydyam P, Choi JY, Prudhomme J, Neal A, Le Roch KG, Ben Mamoun C, Vanderwal CD.   +11 more
europepmc   +5 more sources

Investigation of Calcium Channel Blockers as Antiprotozoal Agents and Their Interference in the Metabolism of Leishmania (L.) infantum. [PDF]

Evid Based Complement Alternat Med, 2016
Reimão JQ, Mesquita JT, Ferreira DD, Tempone AG, Tempone AG.   +4 more
europepmc   +3 more sources

Structure-Activity Relationships of Cinnamate Ester Analogues as Potent Antiprotozoal Agents. [PDF]

ChemMedChem, 2020
Bernal FA, Kaiser M, Wünsch B, Schmidt TJ.   +3 more
europepmc   +2 more sources

Caffeic Acid Phosphanium Derivatives: Potential Selective Antitumor, Antimicrobial and Antiprotozoal Agents. [PDF]

Int J Mol Sci
Lukáč M, Slobodníková L, Mrva M, Dušeková A, Garajová M, Kello M, Šebová D, Pisárčik M, Kojnok M, Vrták A, Kurin E, Bittner Fialová S.   +11 more
europepmc   +3 more sources

Antiprotozoal Agent

, 2020
National Cancer Institute
openalex   +2 more sources