Results 101 to 110 of about 3,281,120 (365)

Spotlight on brexpiprazole and its potential in the treatment of schizophrenia and as adjunctive therapy for the treatment of major depression

Drug Design, Development and Therapy, 2016
Dawn Bruijnzeel, Rajiv Tandon Department of Psychiatry, University of Florida College of Medicine, Gainesville, FL, USA Abstract: Antipsychotic agents, utilized for the treatment of a range of psychiatric disorders, differ substantially in terms of ...
Bruijnzeel D, Tandon R
doaj  

Association of Antipsychotic Polypharmacy vs Monotherapy With Psychiatric Rehospitalization Among Adults With Schizophrenia

JAMA psychiatry, 2019
Importance The effectiveness of antipsychotic polypharmacy in schizophrenia relapse prevention is controversial, and use of multiple agents is generally believed to impair physical well-being.
J. Tiihonen, H. Taipale, J. Mehtälä, P. Vattulainen, C. Correll, A. Tanskanen   +5 more
semanticscholar   +1 more source

Reward learning as a potential target for pharmacological augmentation of cognitive remediation for schizophrenia: a roadmap for preclinical development. [PDF]

, 2013
RationaleImpaired cognitive abilities are a key characteristic of schizophrenia. Although currently approved pharmacological treatments have demonstrated efficacy for positive symptoms, to date no pharmacological treatments successfully reverse cognitive
Acheson, Dean T, Twamley, Elizabeth W, Young, Jared W   +2 more
core   +2 more sources

Prevalence of and factors associated with antipsychotic polypharmacy in patients with serious mental illness: Findings from a cross-sectional study in an upper-middle-income country

Brazilian Journal of Psychiatry
Objective: The aim of our study was to examine the prevalence of and factors associated with antipsychotic polypharmacy (APP) among patients with serious mental illness in the current South African health care context.
Kerryn S. Armstrong, Henk Temmingh
doaj   +1 more source

The Efficacy of Pharmacological Treatment of Depression in Anorexia Nervosa and Underweight Patients: A Systematic Review

European Eating Disorders Review, EarlyView.
ABSTRACT Objective Major depressive disorder (MDD) is a frequent comorbidity in anorexia nervosa (AN). This review aimed to evaluate evidence on the effectiveness of pharmacological treatments for MDD in underweight individuals. Method A systematic review was conducted using PubMed, Medline, PsycINFO, and Web of Science through March 2025.
M. J. Besjes, S. H. W. Mares, A. A. van Elburg, J. Spijker   +3 more
wiley   +1 more source

Factors associated with high‐dose antipsychotic prescriptions in outpatients with schizophrenia: An analysis of claims data from a Japanese prefecture

Neuropsychopharmacology Reports, 2020
Background Antipsychotics are commonly prescribed in high doses in combination with multiple psychotropic drugs. This study focused on the high‐dose antipsychotic prescriptions in patients with schizophrenia, while aiming to identify their associations ...
Tatsuichiro Takahashi, Tetsuya Otsubo, Susumu Kunisawa, Noriko Sasaki, Yuichi Imanaka   +4 more
doaj   +1 more source

Automated identification of Fos expression [PDF]

, 2001
The concentration of Fos, a protein encoded by the immediate-early gene c-fos, provides a measure of synaptic activity that may not parallel the electrical activity of neurons.
Cherkerzian, S., Cohen, B.M., Ennulat, D.J., Evans, M.L., Froimowitz, M.P., Lange, N., Ma, J., Young, D.   +7 more
core   +1 more source

Food Addiction Is Strongly Associated With Psychopathology and Reduced Psychological Well‐Being Among Adults Irrespective of BMI

European Eating Disorders Review, EarlyView.
ABSTRACT Background and Aims Food addiction has been linked to psychopathology and reduced psychological well‐being. Here, we investigated whether these associations are mainly driven by food addiction itself or mediated via an increase in BMI. Methods Data stem from a nationwide survey from Denmark (n = 1474 participants).
Christina Horsager, Emil Færk, Jens Meldgaard Bruun, Marlene B. Lauritsen, Søren Dinesen Østergaard   +4 more
wiley   +1 more source

Psychiatric manifestations of multiple sclerosis and acute disseminated encephalomyelitis [PDF]

, 2006
It is unusual for acute disseminated encephalomyelitis and multiple sclerosis to present as purely psychiatric disorders. We report five patients with such demyelinating diseases and symptoms of psychosis, depression or anxiety.
Brinar, Marko, Brinar, Vesna V., Habek, Mario, Poser, Charles M.   +3 more
core   +1 more source

Making America Healthy Again: Remedies for Robert F. Kennedy Jr.'s Campaign against Chronic Disease

Hastings Center Report, EarlyView.
Abstract Chronic diseases impose enormous health and economic burdens in the United States, especially on marginalized populations, and demand evidence‐based, equity‐focused interventions. To combat chronic disease, the Trump administration established the Make America Healthy Again Commission, chaired by Department of Health and Human Services ...
Lawrence O. Gostin, Alexandra Finch, Peter Lurie   +2 more
wiley   +1 more source