Results 101 to 110 of about 3,264,242 (368)

Prevalence of and factors associated with antipsychotic polypharmacy in patients with serious mental illness: Findings from a cross-sectional study in an upper-middle-income country

Brazilian Journal of Psychiatry
Objective: The aim of our study was to examine the prevalence of and factors associated with antipsychotic polypharmacy (APP) among patients with serious mental illness in the current South African health care context.
Kerryn S. Armstrong, Henk Temmingh
doaj   +1 more source

Clinical applications of personalized medicine: a new paradigm and challenge [PDF]

, 2017
The personalized medicine is an emergent and rapidly developing method of clinical practice that uses new technologies to provide decisions in regard to the prediction, prevention, diagnosis and treatment of disease.
Borro, Marina, DI SANZO, Mariantonia, Fineschi, Vittorio, Frati, Paola, LA RUSSA, Raffaele, Santurro, Alessandro, Scopetti, Matteo, Simmaco, Maurizio   +7 more
core   +1 more source

Comprehensive Qualitative Drug Screening in Emergency Toxicology Using an Automated LC–MSn System:Simultaneous Quantification of Relevant Drugs and Metabolites in Blood Plasma

Drug Testing and Analysis, EarlyView.
Simultaneous qualitative and quantitative analysis of 62 drugs and seven active metabolites in human blood plasma by automated liquid chromatography linear ion trap mass spectrometry. ABSTRACT Rapid and comprehensive qualitative and quantitative analytical procedures are crucial in 24/7 emergency toxicology (ET) to support diagnosis and treatment of ...
Selina Hemmer, Maximilian Ninnig, Lea Wagmann, Sascha K. Manier, Markus R. Meyer   +4 more
wiley   +1 more source

Associations between purine metabolites and clinical symptoms in schizophrenia [PDF]

, 2012
Background: The antioxidant defense system, which is known to be dysregulated in schizophrenia, is closely linked to the dynamics of purine pathway. Thus, alterations in the homeostatic balance in the purine pathway may be involved in the pathophysiology
Debra M. Montrose, George G. Dougherty, Jeffrey K. Yao, Joseph McEvoy, Kenji Hashimoto, Matcheri S. Keshavan, Ravinder D. Reddy, Rima Kaddurah-Daouk, Ruth Condray, Wayne R. Matson   +9 more
core   +3 more sources

Association of Antipsychotic Polypharmacy vs Monotherapy With Psychiatric Rehospitalization Among Adults With Schizophrenia

JAMA psychiatry, 2019
Importance The effectiveness of antipsychotic polypharmacy in schizophrenia relapse prevention is controversial, and use of multiple agents is generally believed to impair physical well-being.
J. Tiihonen, H. Taipale, J. Mehtälä, P. Vattulainen, C. Correll, A. Tanskanen   +5 more
semanticscholar   +1 more source

Mirtazapine Is Associated With Shorter Hospital Stay in Pediatric Avoidant Restrictive Food Intake Disorder—A Retrospective Chart Review

International Journal of Eating Disorders, EarlyView.
ABSTRACT Objective Avoidant restrictive food intake disorder (ARFID) is a relatively new diagnostic entity, and no medication has been approved. Recent data suggest that mirtazapine, a tetracyclic antidepressant, could improve outcomes in ARFID. We conducted a retrospective chart review to examine the effects of mirtazapine on ARFID treatment in youth.
Aman Chishti, Rachael E. Groh, Tamara R. Maginot, Lisa Adler, Megan E. Shott, Walter H. Kaye, Guido K. W. Frank   +6 more
wiley   +1 more source

Moderators and Predictors of Response to Behavior Therapy for Tics in Tourette Syndrome [PDF]

, 2017
Objective: To examine moderators and predictors of response to behavior therapy for tics in children and adults with Tourette syndrome and chronic tic disorders.
Dziura, James, Katsovich, Lily, Peterson, Alan L., Piacentini, John, Scahill, Lawrence, Sukhodolsky, Denis G., Walkup, John T., Wilhelm, Sabine, Woods, Douglas W.   +8 more
core   +2 more sources

Acute Generalized Exanthematous Pustulosis Induced by Olanzapine

Acta Medica, 2006
The case of a 56 years old man is presented, who developed acute generalized exanthematous pustulosis 5 days after the introduction of olanzapine 10 mg.
Susanne Christen, Félix Gueissaz, Romain Anex, Daniele Fabio Zullino   +3 more
doaj   +1 more source

Factors associated with high‐dose antipsychotic prescriptions in outpatients with schizophrenia: An analysis of claims data from a Japanese prefecture

Neuropsychopharmacology Reports, 2020
Background Antipsychotics are commonly prescribed in high doses in combination with multiple psychotropic drugs. This study focused on the high‐dose antipsychotic prescriptions in patients with schizophrenia, while aiming to identify their associations ...
Tatsuichiro Takahashi, Tetsuya Otsubo, Susumu Kunisawa, Noriko Sasaki, Yuichi Imanaka   +4 more
doaj   +1 more source

Development and validation of a GC-MS method for the detection and quantification of clotiapine in blood and urine specimens and application to a postmortem case [PDF]

, 2015
INTRODUCTION: Clotiapine is an atypical antipsychotic of the dibenzothiazepine class introduced in a few European countries since 1970, efficient in treatment-resistant schizophrenic patients.
Busardo', FRANCESCO PAOLO, Catanese, Miriam, Mannocchi, Giulio, Pantano, Flaminia, Tittarelli, Roberta, UMANI RONCHI, Federica   +5 more
core   +5 more sources