Results 101 to 110 of about 56,243 (346)

A novel DRD2 single-nucleotide polymorphism associated with schizophrenia predicts age of onset: HapMap tag-sincle-nucleotide polymorphism analysis [PDF]

, 2012
Background: Dopamine D2 receptor (DRD2) is thought to be critical in regulating the dopaminergic pathway in the brain which is known to be important in the aetiology of schizophrenia. It is therefore not surprising that most antipsychotic medication acts
Hughes, Ian, Lawford, Bruce, Morris, Phillip, Swagell, Christopher, Voisey, Joanne, Young, Ross   +5 more
core   +2 more sources

Synthesis, Characterization, and Bioactivity of Quinoxaline Thiazolotriazoles

Journal of Heterocyclic Chemistry, EarlyView.
Quinoxaline thiazolotriazole target molecules with antibacterial, antitubercular and antidiabetic activity. ABSTRACT A total of 10 quinoxaline thiazolo[2,3‐c][1,2,4]triazole hybrid molecules were synthesized in a four‐step synthetic protocol. Six of these compounds are reported here for the first time.
Silungile Mhlongo, Sibusiso Senzani, Shahidul Islam, Kolawole Olofinsan, Moganavelli Singh, Nirasha Nundkumar, Sithabile Mokoena, Rajshekhar Karpoormath, Neil A. Koorbanally   +8 more
wiley   +1 more source

Measurement of treatment adherence with antipsychotic agents in patients with schizophrenia

Neuropsychiatric Disease and Treatment, 2009
Xinhua S Ren1,2,3, Lawrence Herz4,5, Shirley Qian1,2,3, Eric Smith3,4, Lewis E Kazis1,2,31The Center for the Assessment of Pharmaceutical Practices (CAPP), Boston University School of Public Health, Boston, MA, USA; 2Department of ...
Xinhua S Ren, Lawrence Herz, Shirley Qian, et al   +3 more
doaj  

Animal models of schizophrenia for molecular and pharmacological intervention and potential candidate molecules

Neurobiology of Disease, 2013
Schizophrenia is a severe and common psychiatric disease with a lifetime prevalence of 0.5% to 1% globally. Because of limitations of the experimental approach in humans, valid animal models are essential in the effort to identify novel therapeutics for ...
Akihiro Mouri, Taku Nagai, Daisuke Ibi, Kiyofumi Yamada   +3 more
doaj   +1 more source

Cost-Offsets of New Medications for Treatment of Schizophrenia [PDF]

Broad claims are frequently made that new medications will offset all or part of their costs by reducing other areas of Medicaid spending. In this paper we examine the net impact on spending for new drugs used to treat schizophrenia.
Richard G. Frank, Sharon-Lise Normand, Thomas G. McGuire   +2 more
core  

Exploring the roles and impacts of pharmacists embedded in general practice: a scoping review

Journal of Pharmacy Practice and Research, EarlyView.
Abstract Background The role of the general practice pharmacist (GPP) in Australia is not yet clearly defined, and their clinical expertise remains underutilised in general practice settings. This may be attributed to a limited understanding of pharmacists' capabilities, which can hinder optimal GPP utilisation.
Christel Chandra, Brooke Bevis, Nazanin Falconer, Holly Foot   +3 more
wiley   +1 more source

Antipsychotic Drug Poisoning in Children Under 12 Years Old in Loghman-Hakim Hospital During 2016-2022

International Journal of Medical Toxicology and Forensic Medicine
Background: Unintentional pediatric poisoning with antipsychotic medications represents an important clinical entity. This study aimed to evaluate the epidemiology, clinical manifestations, and outcomes of antipsychotic poisoning among children ...
Fariba Farnaghi, Pooya Eini, Latif Gachkar   +2 more
doaj   +1 more source

ANTIPSYCHOTIC AGENTS IN ANXIETY DISORDERS: AN UMBRELLA REVIEW [PDF]

Int J Neuropsychopharmacol
Rafael C. Freire, Amir Garakani, Frank D. Buono, Mona Salehi, Melissa Funaro, Anna Klimowicz, Harshit Sharma, Clara V. Faria, Kaitlyn Larkin   +8 more
europepmc   +2 more sources

Antithrombin: Deficiency, Diversity, and the Future of Diagnostics

Mass Spectrometry Reviews, EarlyView.
ABSTRACT Our healthcare system provides reactive sick‐care, treating patients after symptoms have appeared by prescription of generic and often suboptimal therapy. This strategy brings along high costs and high pressure which is not sustainable.
Mirjam Kruijt, Christa M. Cobbaert, L. Renee Ruhaak   +2 more
wiley   +1 more source

The pharmacist’s response to the needs of patients undergoing treatment with psychotropic medication [PDF]

, 1999
The usage of psychotropic (Table 1) medication is considerable world wide. In Malta, this can be attested to by the numerous studies that have been conducted by the University of Malta Department of Pharmacy (in conjuction with other institutions and ...
Sant Fournier, Mary Ann
core