Results 11 to 20 of about 25,654 (163)

Integrated Phytochemical Characterisation, Pharmacological Evaluation and Computational Investigation of <i>Acampe papillosa</i> Stem Extract. [PDF]

Anal Sci Adv
The pharmacological potential of the methanolic stem extract of Acampe papillosa is evaluated using in vivo and in silico approaches. The extract demonstrates significant anxiolytic, sedative, anti‐inflammatory, and antipyretic activities in experimental models, while molecular docking supports the observed biological effects through favorable ...
Sadia QA, Tamim ST, Tashriq FM, Uddin N, Hima FZA, Surat US, Khastagir M, Jalil MA, Rasel MH, Rafi AU, Hossen SMM.   +10 more
europepmc   +2 more sources

Combinatorial targeting of G‐protein‐coupled bile acid receptor 1 and cysteinyl leukotriene receptor 1 reveals a mechanistic role for bile acids and leukotrienes in drug‐induced liver injury

Hepatology, EarlyView., 2022
CHIN117 is a dual cysteinyl leukotriene receptor 1 (CYSLTR1) antagonist and G‐protein‐coupled bile acid receptor 1 (GPBAR1) agonist. In the liver, GPBAR1 and CYSLTR1 are coexpressed by liver sinusoidal endothelial cells (LSECs), HSCs, circulating monocytes/macrophages, and liver resident macrophages (Kupffer cells).
Michele Biagioli, Silvia Marchianò, Cristina di Giorgio, Rosalinda Roselli, Martina Bordoni, Rachele Bellini, Bianca Fiorillo, Valentina Sepe, Bruno Catalanotti, Chiara Cassiano, Maria Chiara Monti, Eleonora Distrutti, Angela Zampella, Stefano Fiorucci   +13 more
wiley   +1 more source

Antipyretic therapy in critically ill patients with sepsis: an interaction with body temperature. [PDF]

PLoS ONE, 2015
The effect of antipyretic therapy on mortality in patients with sepsis remains undetermined. The present study aimed to investigate the role of antipyretic therapy in ICU patients with sepsis by using a large clinical database.The multiparameter ...
Zhongheng Zhang, Lin Chen, Hongying Ni
doaj   +1 more source

Chemical Profiling, Pharmacological Insights and In Silico Studies of Methanol Seed Extract of Sterculia foetida

Plants, 2021
Sterculia foetida, also known as jangli badam in Bangladesh, is a traditionally used plant that has pharmacological activities. A qualitative phytochemical analysis was performed to assess the metabolites in a methanolic extract of S. foetida seeds (MESF)
Najmul Alam, Naureen Banu, Md. Arfin Ibn Aziz, Niloy Barua, Umme Ruman, Israt Jahan, Farhana Jahan Chy, Susmita Denath, Arkajyoti Paul, Md. Nazim Uddin Chy, Mohammed Aktar Sayeed, Talha Bin Emran, Jesus Simal-Gandara   +12 more
doaj   +1 more source

Antinociceptive and antipyretic activities of extracts and fractions from Dracaena loureiri in experimental animals [PDF]

Songklanakarin Journal of Science and Technology (SJST), 2003
Dried coarsely powdered material from the stem woods of Dracaena loureiri Gagnep (D loureiri) has extracted with hexane and methanol to give hexane and methanol extracts, respectively. The methanol extract was roughly separated into four fractions.
Pisit Bouking, Sanan Subhadhirasakul, Wantana Reanmongkol   +2 more
doaj  

Antihyperlipidemic, anti-inflammatory, analgesic, and antipyretic activities of “dimethyl dimethoxy biphenyl dicarboxylate” in male Wistar rats

Journal of Advanced Pharmaceutical Technology & Research, 2022
Dimethyl dimethoxy biphenyl (DDB) dicarboxylate has been applied as a therapeutic modality for curing liver diseases, particularly hepatitis virus. The objective of this study was to assess the protective potential against Triton X-100 induced abnormal ...
Heba M. I. Abdallah, Gihan F Asaad, Mahmoud S Arbid, Yousra A Nomier   +3 more
doaj   +1 more source

Antipyretic activity of the extracts of Hibiscus sabdariffa calyces L. in experimental animals [PDF]

Songklanakarin Journal of Science and Technology (SJST), 2007
The effects of the extracts from Hibiscus sabdariffa calyces L. (H. sabdariffa) on nociceptive response using writhing, hot plate and formalin test in mice and the antipyretic activity in yeast-induced fever in rats, were examined.
Wantana Reanmongkol, Arunporn Itharat
doaj  

Study on the Antipyretic and Anti-inflammatory Mechanism of Shuanghuanglian Oral Liquid Based on Gut Microbiota-Host Metabolism

Frontiers in Pharmacology, 2022
Nowadays, there has been increased awareness that the therapeutic effects of natural medicines on inflammatory diseases may be achieved by regulating the gut microbiota. Shuanghuanglian oral liquid (SHL), the traditional Chinese medicine preparation, has
Yan Gao, Lu Liu, Chen Li, Yu-Ting Liang, Jing Lv, Long-Fei Yang, Bo-Nian Zhao   +6 more
doaj   +1 more source

The Phytochemical and Biological Investigation of Jatropha pelargoniifolia Root Native to the Kingdom of Saudi Arabia

Molecules, 2018
Extensive phytochemical analysis of different root fractions of Jatropha pelargoniifolia Courb. (Euphorbiaceae) has resulted in the isolation and identification of 22 secondary metabolites.
Hanan Y. Aati, Ali A. El-Gamal, Oliver Kayser, Atallah F. Ahmed   +3 more
doaj   +1 more source

Analgesic and Antipyretic Effects of Red Dragon Fruit (Hylocereus polyrhizus) Peel Extract in White Male Rats

Majalah Obat Tradisional, 2022
Red dragon fruit (Hylocereus polyrhizus) is a tropical fruit that is currently cultivated in all tropical parts of the world. It is popular to consume its fruit flesh, while the peel is often thrown away.
Betharia Lorenza Br Subakti, Chrismis Novalinda Ginting, Linda Chiuman   +2 more
doaj   +1 more source