Results 21 to 30 of about 25,654 (163)

Physicochemical and pharmacological assessment of a traditional biomedicine: Mukta shouktic bhasma [PDF]

Songklanakarin Journal of Science and Technology (SJST), 2009
Mukta shouktic bhasma (MSB) is a traditional Ayurvedic medicinal preparation. This biomedicine is synthesized through special calcination of mother of pearl as mentioned in the classical Ayurvedic text. Physicochemical characterization of MSB was carried
Nitin Dubey, Nidhi Dubey, Rajendra S. Mehta, Ajay K. Saluja, Dinesh K. Jain   +4 more
doaj  

Long-term health effects of antipyretic drug use in the ageing population: protocol for a systematic review [version 1; peer review: 2 approved]

F1000Research, 2020
Background: Fever is suppressed with drugs due to discomfort and risk of organ damage. However, there is some compelling evidence for the benefits of fever. The elderly are a special population in this regard as they have a blunted fever response.
Mahesh Mallappa, George Vithoulkas, Seema Mahesh, Esther van der Werf, Nai Ming Lai   +4 more
doaj   +1 more source

Pharmacological evaluation of anti-inflammatory, antipyretic, analgesic, and antioxidant activities of Castanopsis costata leaf fractions (water, ethyl acetate, and n-hexane fractions): the potential medicinal plants from North Sumatra, Indonesia

Research in Pharmaceutical Sciences
Background and purpose: Inflammation, fever, and pain can be associated with several diseases, and the synthetic drugs used in the treatment of these conditions often have severe side effects.
Maulana Yusuf Alkandahri, Asman Sadino, Barolym Tri Pamungkas, Zulpakor Oktoba, Maya Arfania, Nia Yuniarsih, Eko Sri Wahyuningsih, Dea Eka Putri   +7 more
doaj   +1 more source

Mechanism Assay of Honeysuckle for Heat-Clearing Based on Metabolites and Metabolomics

Metabolites, 2022
Nonsteroidal anti-inflammatory drugs (NSAIDs), such as cyclooxygenase (Cox)-1/2 inhibitor, have emerged as potent antipyretics and analgesics. However, few herbs with Cox-1/2 inhibitory activity are commonly used for heat-clearing in China.
Hechen Wang, Lu Tian, Yiman Han, Xiaoyao Ma, Yuanyau Hou, Gang Bai   +5 more
doaj   +1 more source

Efficacy, safety and cost‐effectiveness of CAR‐T therapy

British Journal of Clinical Pharmacology, EarlyView.
CAR T‐cells demonstrate high efficacy in blood cancers, including ALL, MM and DLBCL. Innovations target solid tumours despite challenges such as antigen escape. Combination therapies enhance the delivery and infiltration of CAR T cells. Toxicity, cost and resistance remain major barriers to clinical use.
Emina Karahmet Sher, Amina Džidić‐Krivić, Emma Pinjic, Nejra Selak, Kanita Omerbasic, Alexandar Chupin, Andrej Belancic, Almir Fajkic   +7 more
wiley   +1 more source

Evaluating a virtual paediatric adverse drug reaction clinic

British Journal of Clinical Pharmacology, EarlyView.
Aims Adverse drug reactions (ADRs) are a common problem in paediatric health care. There is limited access to expertise in the evaluation and management of potential ADRs in children, limiting access to these services and creating delays in assessment and management.
Emily Hauck, Blanca Del Pozzo‐Magana, Michael Rieder   +2 more
wiley   +1 more source

Maternal Dipyrone Exposure and Risk of Major Congenital Malformations, Adverse Perinatal and Postnatal Outcomes: A Population‐Based Cohort Study

Clinical Pharmacology &Therapeutics, EarlyView.
Pain and fever are common in pregnancy. Dipyrone is widely used in Europe, Latin America, and parts of Asia, but is banned in other countries due to concerns about agranulocytosis. Evidence on its safety in pregnancy remains limited and inconsistent. This study aimed to evaluate whether maternal dipyrone use during the first‐ and third‐trimesters is ...
Itamar Ben Shitrit, Daphna Idan, Ariel Avraham Hasidim, Tal Michael, Amalia Levy, Gali Pariente, Eitan Lunenfeld, Sharon Daniel   +7 more
wiley   +1 more source

Bioactive Potential and COX-2 Interaction of Ajuga iva (L.) Schreb. Hydroalcoholic Extract: Evidence from Experimental and Computational Studies

Molecules
Ajuga iva (L.) Schreb. is traditionally used in North African ethnomedicine for the management of inflammation, pain, and fever. The present study aimed to characterize the phytochemical profile of the hydroalcoholic extract of its aerial parts and to ...
Yousra Boutora, Samira Boussekine, Ouided Benslama, Sabrina Lekmine, Nedjwa Mansouri, Nabil Touzout, Hamza Moussa, Rania Gacem, Najla Hfaiedh, Gema Nieto   +9 more
doaj   +1 more source

Sol–gel synthesis of ZnO@SiC heterojunctions from photovoltaic waste for enhanced paracetamol photodegradation

Environmental Progress &Sustainable Energy, EarlyView.
Abstract Exponential growth in photovoltaic energy production has created a critical environmental challenge: managing silicon carbide (SiC) waste from wafer cutting processes. This study addresses this challenge by transforming photovoltaic waste into high‐value photocatalytic materials.
Hajer Aloulou, Mohamed Romdhani, Wala Aloulou, Raja Ben Amar   +3 more
wiley   +1 more source

Comparative evaluation of the antipyretic and analgesic efficacy and safety of a fast-release paracetamol 650 mg formulation vs. conventional paracetamol formulations in adults with acute febrile or febrile-pain conditions: a multicenter randomized controlled trial

Frontiers in Pain Research
AimParacetamol is widely used for management of fever/pain. With increasing emphasis on rapid symptom relief, this study compared the response following a single 650 mg oral dose of four commercially available tablets in acute febrile and febrile-pain ...
Susobhan Mondal, S. K. Ashik Ikbal, Sumit Agrawal, Amar Raykantiwar, Avirath Acchammachary, Suhas Kalashetti, K. R. Shivaprasad, Ashok V B, Mukulesh Gupta, Vikas Verma, Monjori Mitra, Amitrajit Pal, Dattatray Pawar, Akhilesh Sharma   +13 more
doaj   +1 more source