Results 201 to 210 of about 275,477 (365)

Antisense oligonucleotide inhibition of acetylcholinesterase gene expression induces progenitor cell expansion and suppresses hematopoietic apoptosis ex vivo.

, 1994
Hermona Soreq, Deborah Patinkin, Efrat Lev-Lehman, Mirta Grifman, Dalia Ginzberg, F. Eckstein, H Zakut   +6 more
openalex   +1 more source

Inhibition of the erbB-2 Tyrosine Kinase Receptor in Breast Cancer Cells by Phosphoromonothioate and Phosphorodithioate Antisense Oligonucleotides [PDF]

, 1996
James P. Vaughn, J. Stekler, Samuel H. Demirdji, Jane K. Mills, Marvin H. Caruthers, J. Dirk Iglehart, Jeffrey R. Marks   +6 more
openalex   +1 more source

Antisense Oligonucleotides

Definitions, 2020

semanticscholar   +1 more source

Patient‐Reported Outcomes in the Phase III OASIS‐HAE Study of Donidalorsen for Hereditary Angioedema

Allergy, EarlyView.
We report an overview of patients' self‐reported quality of life, disease control, and functioning in daily life while taking donidalorsen for HAE in the 24‐week phase 3 OASIS‐HAE trial. Most patients reported clinically meaningful improvements in quality of life and disease control.
Marc A. Riedl, Aaron Yarlas, Laura Bordone, Sabrina Treadwell, Sophie Wang, Kenneth B. Newman, Danny M. Cohn   +6 more
wiley   +1 more source

Antisense oligonucleotides to Cux-1, a Cut-related homeobox gene, cause increased apoptosis in mouse embryonic kidney cultures. [PDF]

, 1997
Susan E. Quaggin, Herman Yeger, Peter Igarashi   +2 more
openalex   +1 more source

Expansion of Splice-Switching Therapy with Antisense Oligonucleotides. [PDF]

Int J Mol Sci
Takeshima Y.
europepmc   +1 more source

Discovery of natural product derivative triptolidiol as a direct NLRP3 inhibitor by reducing K63‐specific ubiquitination

British Journal of Pharmacology, EarlyView.
▪ Background and Purpose NLRP3 is up‐regulated in inflammatory and autoimmune diseases. The development of NLRP3 inhibitors is challenged by the identification of compounds with distinct mechanisms of action avoiding side effects and toxicity. Triptolide is a natural product with multiple anti‐inflammatory activities, but a narrow therapeutic window ...
Mo‐Yu Ding, Chengqing Ning, Shao‐Ru Chen, Hao‐Ran Yin, Jing Xu, Ying Wang   +5 more
wiley   +1 more source

Effect of Antisense Oligonucleotides against Cholesteryl Ester Transfer Protein on the Development of Atherosclerosis in Cholesterol-fed Rabbits [PDF]

, 1998
Masahiro Sugano, Naoki Makino, Shojiro Sawada, Shoji Otsuka, Miha Watanabe, Hiroshi Okamoto, Masafumi Kamada, Atsushi Mizushima   +7 more
openalex   +1 more source

SNA-modified antisense oligonucleotides: A new pathway for renal targeting? [PDF]

Mol Ther Nucleic Acids
Dumoulin B, Yamada K, Susztak K.
europepmc   +1 more source

Site‐specific m6A‐miR‐494‐3p, not unmethylated miR‐494‐3p, compromises blood brain barrier by targeting tight junction protein 1 in intracranial atherosclerosis

British Journal of Pharmacology, EarlyView.
Background and Purpose Intracranial atherosclerosis is one of the most common causes of ischaemic stroke. However, there is a substantial knowledge gap on the development of intracranial atherosclerosis. Intracranial arteries are characterized by an upregulation of tight junctions between endothelial cells, which control endothelial permeability.
Tamar Woudenberg, M. Leontien van der Bent, Veerle Kremer, Ingeborg S. E. Waas, Mat J. A. P. Daemen, Reinier A. Boon, Paul H. A. Quax, A. Yaël Nossent   +7 more
wiley   +1 more source