Results 201 to 210 of about 127,002 (321)

Structural Characterization of <i>DDX23</i> 5' UTR Regulatory Elements and Their Targeting by LNA-Modified Antisense Oligonucleotides. [PDF]

Int J Mol Sci
Kamzeeva P, Shepelev N, Zabbarova V, Brylev V, Chistov A, Ryazantsev D, Kot E, Novopashina D, Rubtsova M, Aralov A.   +9 more
europepmc   +1 more source

Lack of QT Prolongation for 2′-O-Methoxyethyl-Modified Antisense Oligonucleotides Based on Retrospective Exposure/Response Analysis of Ten Phase 1 Dose-Escalation Placebo-Controlled Studies in Healthy Subjects [PDF]

, 2017
Rosie Z. Yu, Rudy Gunawan, Richard S. Geary, Steven G. Hughes, Scott P. Henry, Yanfeng Wang   +5 more
openalex   +1 more source

Wheat TaSPL13‐2B Improves Floret Fertility and Enhances Grain Number per Spikelet Through Jasmonic Acid Signalling Pathway

Plant Biotechnology Journal, EarlyView.
ABSTRACT Floret fertility is a key determinant of grain number per spike and an important factor in cereal crop yield. However, the mechanisms by which phytohormone signalling and transcription factors coordinately regulate floret fertility and spikelet development are not well understood, especially in wheat.
Li Li, Fu Shi, Yaqiong Wang, Yanbin Guan, Ya'nan Wu, Ling Chen, Junli Chang, Mingjie Chen, Jun Xiao, Guangxiao Yang, Yuesheng Wang, Guangyuan He, Yin Li   +12 more
wiley   +1 more source

Enhancing the intracellular delivery of antisense oligonucleotides (ASO) : a comparative study of aptamer, vitamin E, and cholesterol ASO conjugates. [PDF]

RSC Adv
Balachandran AA, Poudel BH, Rahimizadeh K, Chikkanna A, Veedu RN.   +4 more
europepmc   +1 more source

Design of antisense oligonucleotides

Folia Pharmacologica Japonica, 2016
Satoshi, Obika, Yuuya, Kasahara
openaire   +3 more sources

Selective targeting of MYC by antisense oligonucleotides

, 2018
Taylor Gill
openalex   +1 more source

Rare Natural SNP Activates SHOOT APICAL MERISTEM ENLARGER1 to Increase Branch Number and Silique Number on the Main Inflorescence in Brassica napus

Plant Biotechnology Journal, EarlyView.
ABSTRACT Brassica napus is the second most important oil crop worldwide. Number of primary branches (Branch number, BN) and silique number on the main inflorescence (SMI) are key yield‐related quantitative traits. Here, we cloned a major QTL, qDB.A09, which simultaneously influences BN and SMI.
Sihao Zhang, Bao Li, Xiaoting Li, Song Yu, Yebitao Yang, Peipei Liu, Tanglingdian He, Wei Wang, Mei Li, Liang Guo, Jinxing Tu   +10 more
wiley   +1 more source

ASOptimizer: optimizing chemical diversity of antisense oligonucleotides through deep learning. [PDF]

Nucleic Acids Res
Kang S, Lee D, Hwang G, Lee K, Kang M.
europepmc   +1 more source

Synthesis and evaluation of (S)-5′-C-aminopropyl and (S)-5′-C-aminopropyl-2′-arabinofluoro modified DNA oligomers for novel RNase H-dependent antisense oligonucleotides

, 2020
Yujun Zhou, Ryohei Kajino, Seiichiro Ishii, Kenji Yamagishi, Yoshihito Ueno   +4 more
openalex   +2 more sources

Antisense oligonucleotides to class III β-tubulin sensitize drug-resistant cells to Taxol [PDF]

, 1999
Maria Kavallaris, Catherine A. Burkhart, Susan Band Horwitz   +2 more
openalex   +1 more source