Results 71 to 80 of about 1,671 (202)

Clinical management and outcomes for 51 Pugs reportedly diagnosed with protein‐losing enteropathy using VetCompass primary care veterinary data

Journal of Small Animal Practice, EarlyView.
Objectives To report the clinicopathological findings, treatment and outcomes of Pugs diagnosed with protein‐losing enteropathy using VetCompass primary care clinical data in the UK and to determine if referral or any specific treatments for protein‐losing enteropathy were associated with outcome. Materials and Methods Retrospective VetCompass study of
A. Kathrani, D. C. Brodbelt, D. B. Church, D. G. O’Neill   +3 more
wiley   +1 more source

Thrombin Inhibitors from Different Animals [PDF]

, 2010
Venous and arterial thromboembolic diseases are still the most frequent causes of death and disability in high-income countries. Clinical anticoagulants are inhibitors of enzymes involved in the coagulation pathway, such as thrombin and factor Xa ...
Tanaka-Azevedo, A. M., Morais-Zani, K., Torquato, R. J. S. [UNIFESP], Tanaka, A. S. [UNIFESP]   +3 more
core   +1 more source

Dried plasma retains hemostatic function and thermal stability during Arctic military operations

Transfusion, EarlyView.
Abstract Background Dried plasma offers a practical alternative for remote damage control resuscitation, providing hemostatic support and volume replacement. The Arctic presents challenges that necessitate the need for blood‐based resuscitation to extend the “golden hour.” To address this, we evaluated the hemostatic and thermal stability of dried ...
Kanwal Singh, Aron A. Shoara, Henry T. Peng, Viktor Prifti, Katy Moes, Cerys McGuinness, Tristan Bonnici, Maria Shiu, Sushmaa Chandralekha Selvakumar, Peter Andrisani, Pierre‐Marc Dion, Damien Miller, Sebastian Vuong, Colin A. Kretz, Philip J. Wallace, Shawn G. Rhind, Wendy Sullivan‐Kwantes, Andrew N. Beckett   +17 more
wiley   +1 more source

Estrogen as a therapeutic agent: Targeting endotheliopathy and coagulopathy in trauma

Transfusion, EarlyView.
Abstract Background Traumatic injury remains a leading cause of death, often due to uncontrolled hemorrhage and trauma‐induced coagulopathy (TIC). TIC is critically triggered by the endotheliopathy of trauma, involving endothelial cell injury and glycocalyx degradation. Despite conventional advances, the stable casualty rate underscores the urgent need
Niruktha Raghavan, Mira Patel, Bryan A. Cotton, Julia Coleman, Donald Jenkins   +4 more
wiley   +1 more source

An assessment of green plasma: The in vitro hemostatic superiority of a currently discarded blood product

Transfusion, EarlyView.
Abstract Introduction Recent studies have linked trauma patient outcomes to the plasma donor's sex, with premenopausal females associated with improved survival and lower organ failure. Currently, green‐colored plasma (due to oral contraceptive use) is removed from the donor pool. We set out to evaluate the hemostatic potential of green plasma.
Samantha C. Redden, David J. Sun, Yao‐Wei W. Wang, Elizabeth Hartwell, Jessica C. Cardenas, Scott D. Olson, Bryan A. Cotton   +6 more
wiley   +1 more source

［総説］Rational Design to Develop Antithrombotic Drugs from the Relationship between the Structure and Function of $ \alpha $ thrombin [PDF]

, 2006
Many protease inhibitors in the circulating blood inhibit the activity of $ \alpha $-thrombin. Inhibition of $ \alpha $-thrombin by antithrombins is attributable to the characteristics of structural relationships between $ \alpha $-thrombin and ...
Bae, Maen, Kimura, Yasutaka, Kosugi, Tadayoshi, Motomura, Makoto, Nakamura, Kazunao, Nakamura, Mariko, Nakasone, Toshiyuki, Ohta, Shigeto, Shimada, Seiji, Sunagawa, Masanori, Takara, Shigeru, Tamaki, Minao, Tengan, Hiroatsu, Uehara, Ken, Yoshioka, Miwa   +14 more
core  

Antithrombotic treatment after stroke due to intracerebral haemorrhage [PDF]

, 2017
BACKGROUND: Survivors of stroke due to intracerebral haemorrhage (ICH) are at risk of thromboembolism. Antithrombotic (antiplatelet or anticoagulant) treatments may lower the risk of thromboembolism after ICH, but they may increase the risks of bleeding ...
Al-Shahi Salman, Rustam, Berge, Eivind, Bowditch, Joshua, Forfang, Elisabeth, Hankey, Graeme J, Perry, Luke A, Rønning, Ole Morten, Villanueva, Elmer   +7 more
core   +1 more source

Low serum transferrin predicts adverse outcome in COVID‐19 and is related to coagulation activity

British Journal of Haematology, EarlyView.
Lukas Lanser, Francesco Robert Burkert, Lis Thommes, Rosa Bellmann‐Weiler, Guenter Weiss   +4 more
wiley   +1 more source

Declaring futility after traumatic injury and the burden of failure on the surgeon

Transfusion, EarlyView.
Abstract In this edition of the THOR supplement in Transfusion, there are two articles that deal with resuscitation futility and transfusion. In one article, Yazer et al. delve into the details of the studies outlined in this editorial and summarize the literature on the topic of transfusion and futility. The second article by Dr.
Jan‐Michael Van Gent, Bryan A. Cotton
wiley   +1 more source

The impact of rapid infusers on the hemostatic potential of cryoprecipitate products

Transfusion, EarlyView.
Abstract Background In cases of massive transfusion, intravenous access can be limited. Additionally, delivering different products through separate lines and infusion methods adds unnecessary steps. RBC, plasma, and whole blood (WB) are delivered via rapid infusers; cryoprecipitate (CRYO) is infused through separate access and is not approved with ...
Connor D. Purvis, Samantha Redden, Andrew Jacobson, Yao‐Wei Wang, Julie Campbell, Jessica Cardenas, Jan‐Michael Van Gent, Bryan A. Cotton   +7 more
wiley   +1 more source