Results 41 to 50 of about 6,430 (232)
Peri-operative concerns in a patient with thyroid storm secondary to molar pregnancy
Awareness of the presence of thyroid function abnormalities in patients with molar pregnancy is important for its prompt diagnosis and management. We report the development of thyroid storm in the immediate post-operative period in a 25-year-old female ...
Tanvir Samra +3 more
doaj +1 more source
ABSTRACT Amiodarone therapy may induce thyroid dysfunction in approximately 20% of patients, either amiodarone‐induced hypothyroidism (AIH) or thyrotoxicosis (AIT). Both situations may occur at any time during treatment or even months to years after drug withdrawal due to tissue storage with slow systemic release.
Daniela M. Soares, Lia Ferreira
wiley +1 more source
The cis‐2,3‐bis(trifluoromethyl)cyclopropyl chemotype is introduced. The steric demand of this motif is intermediate between that of the heptafluoroisopropyl and prefluorotertbutyl groups; yet, it induces significantly less lipophilicity than these due to its facial polarity.
Daniel Gaviña +5 more
wiley +1 more source
TSHR‐Targeting Nucleic Acid Aptamer Treats Graves' Ophthalmopathy via Novel Allosteric Inhibition
This study presents YC3, a novel inhibitory TSHR‐targeting aptamer, as a promising therapeutic for Graves' ophthalmopathy (GO). YC3 suppresses pathological phenotypes in human orbital fibroblasts and improves outcomes in GO mice by binding to a previously unidentified allosteric site on TSHR, demonstrating the potential of aptamers in advancing ...
Yanchen Zhang +16 more
wiley +1 more source
ABSTRACT Sinomenine, derived from Sinomenium acutum, is widely used in inflammatory diseases. However, its risk of inducing agranulocytosis is not widely appreciated. We report a life‐threatening case in a 40‐year‐old woman with chronic kidney disease (CKD; baseline estimated glomerular filtration rate [eGFR] as low as 36 mL/min/1.73 m2) who developed ...
Ping Xin, Ruoyan Liu, Yu Zhang, Bin Fu
wiley +1 more source
Model predictive control for the prescription of antithyroid agents
2 ...
Menzel, Maylin +3 more
openaire +2 more sources
Henoch–Schönlein Purpura (IgA Vasculitis) in Association with Thyrotoxicosis
Graves’ disease is the most common cause of hyperthyroidism, which is characterized by thyroid antibodies and the following clinical manifestations: goiter, ophthalmopathy, and pretibial myxedema.
Mojgan Sanjari +2 more
doaj +1 more source
Update on medication-overuse headache and its treatment [PDF]
OPINION STATEMENT: Medication-overuse headache-i.e., a too-frequent consumption of acute headache medications leading to increased headache frequency and reduced effectiveness of acute and preventive treatments-is a serious medical condition whose ...
Giamberardino MA +2 more
core +1 more source
This study updated safety evidence on ICS and LABA use in pregnant women with asthma. After adjusting confounders, there was no association between ICS or LABA use and adverse fetal outcomes. However, high‐dose ICS exposure was associated with a higher risk of congenital anomalies among ICS users.
Yea‐Chwen Wu +3 more
wiley +1 more source
Antithyroid drug-induced agranulocytosis [PDF]
Thyrotoxicosis is a common endocrine disorder. Antithyroid drug therapy is the standard treatment for this disease, especially in young women of reproductive age. A serious side effect of antithyroid drug use, however, is agranulocytosis.
Lee, CH, Liang, RHS
core

