Results 51 to 60 of about 1,547,833 (172)

Synthesis and Cytotoxic Activity of 1,3‐Selenazole‐2‐Amine Derivatives With Computational ADMET Profiling

ChemistryOpen, Volume 15, Issue 10, October 2026.
Four novel 1,3‐selenazole‐2‐amine derivatives were synthesized and evaluated in HT‐29, MCF‐7, and L929 cell lines. Compound 4 showed the highest MCF‐7 cytotoxicity. Compound 3 displayed low L929 toxicity. In silico ADMET predicted favorable pharmacokinetic properties.
Gulay Dilek, Senem Akkoc
wiley   +1 more source

Carbimazole induced agranulocytosis with life-threatening complications, tremendous response with granulocyte-colony stimulating factor

Medical Journal of Dr. D.Y. Patil University, 2016
Agranulocytosis is a rare complication of drug carbimazole (0.23%). We are accounting to present a very interesting and rare case of agranulocytosis and neutropenic sepsis secondary to carbimazole that have tremendous response with recombinant human ...
Seema Mahant, Upasana Shobhane, P D Mahant   +2 more
doaj   +1 more source

Low Preoperative Free Triiodothyronine, Particularly in Females, Is Associated With Reduced Weight Loss and Diabetes Remission After Bariatric Surgery in Euthyroid Adults

Diabetes/Metabolism Research and Reviews, Volume 42, Issue 6, September 2026.
ABSTRACT Aims With the rising prominence of GLP‐1 receptor agonists, identifying predictors of optimal bariatric surgery candidates has become increasingly important. We investigated cross‐sectional relationships between thyroid hormones and obesity‐related parameters, and evaluated the predictive value of baseline thyroid hormones for weight loss (WL)
Shaobo Li, Yinfang Tu, Hongwei Zhang, Yunfeng Xiao, Yuqian Bao, Jun Yin, Yujin Ma, Haoyong Yu, Fengjing Liu   +8 more
wiley   +1 more source

Drug‐Induced Vitiligo: FDA Adverse Events Reporting System (FAERS) and Canada Vigilance Adverse Reaction (CAVR) Database Analysis and Literature Review

Journal of Cosmetic Dermatology, Volume 25, Issue 9, September 2026.
ABSTRACT Background Vitiligo is a common chronic acquired pigmentation disease, that usually occurs with an asymptomatic whitish patch or macule. Although previous studies have reported several cases of drug‐induced vitiligo, there are few comprehensive studies determining the drugs that induce vitiligo.
Yuhao Li, Yi Ou, Luyue Chang, Ruiyao Wang, Xinyi Shao, Jingbo Zhang, Jin Chen   +6 more
wiley   +1 more source

Responses to antithyroid drugs and serum s(P)RR in patients with Graves’ disease.

, 2018
Responses to antithyroid drugs and serum s(P)RR in patients with Graves’ disease.
Shihori Kimura (5066948), Atsuhiro Ichihara (392936), Midori Yatabe (5066942), Kaoru Yamashita (5066951), Takashi Ando (381000), Junichi Yatabe (625892), Yasufumi Seki (5066945), Daisuke Watanabe (201397), Yuki Mizuguchi (5066957), Kanako Bokuda (479682), Satoshi Morimoto (392931), Noriyoshi Takano (5066954)   +11 more
core   +1 more source

Extrathyroidal actions of Antithyroid Thionamides

, 2002
Some compounds having thionamide structure inhibit thyroid functions. Such antithyroid thionamides include mercaptomethylimidazole (methimazole), thiourea and propylthiouracil, of which mercaptomethylimidazole is widely used to treat hyperthyroidism ...
Biswas, Kausik, Banerjee, Ranajit K, Bandyopadhyay, Uday, Ranajit K. Banerjee, Kausik Biswas, Uday Bandyopadhyay   +5 more
core   +1 more source

Hashimoto's encephalopathy (a brief review of literature and a clinical case)

Неврология, нейропсихиатрия, психосоматика, 2019
Hashimoto's encephalopathy (HE) is a steroid-responsive encephalopathy associated with autoimmune thyroiditis; it is based on the inflammatory brain process associated with a cross-reaction to anti-thyroid autoantibodies.
М. A. Kutlubaev, O. V. Gekhtman, E. N. Zakirova   +2 more
doaj   +1 more source

Medications for treatment of cardiological complications before the antithyroid therapy and after the follow-up.

, 2015
Medications for treatment of cardiological complications before the antithyroid therapy and after the follow-up.
Iryna Tsymbaliuk (710482), Andrii Dinets (710485), Nataliia Shvets (710484), Dmytro Unukovych (710483)   +3 more
core   +1 more source

Drug-Induced Liver Injury: A Unique Presentation of Single-Dose Administration of Propylthiouracil

Journal of Investigative Medicine High Impact Case Reports, 2020
Antithyroid drug-induced severe liver injury is an uncommon but serious complication. We hereby delineate the case of a 38-year-old female who presented to the emergency department for an impending thyroid storm.
Simcha Weissman DO, Nishan G. Rajaratnam MD, Nabeel Qureshi MD, Faisal Inayat MBBS, Sameh Elias MD, FACP   +4 more
doaj   +1 more source

Beyond Glucocorticoids: The Current Landscape and Prospects for Treating Immune Checkpoint Inhibitor‐Induced Autoimmunity

ACR Open Rheumatology, Volume 8, Issue 8, August 2026.
The rapid integration of immune checkpoint inhibitors (ICIs) into standard oncology protocols has birthed a new frontier in clinical rheumatology: immune‐related adverse events (irAEs). By disrupting the programmed cell death‐1 (PD‐1)/PD‐L1 and cytotoxic T‐lymphocyte‐associated protein 4 (CTLA‐4) axes to restore antitumor T cell activity, these ...
Xizi Hu, Ji Eun Ryoo, Brian S. Henick, Adam Mor   +3 more
wiley   +1 more source