Results 31 to 40 of about 3,970 (174)

Tumor Infiltrating Lymphocyte Therapy Combined With PD‐1/LAG‐3 Inhibition in Patients With Recurrent Platinum‐Resistant Ovarian Cancer

International Journal of Cancer, EarlyView.
The detection of tumor‐infiltrating lymphocytes (TILs) is a positive prognostic factor in ovarian cancer. Moreover, TILs are significantly boosted by immunotherapy, though ovarian cancer patients have seen limited benefit from immune therapies. This study investigated the safety and feasibility of TIL therapy combined with PD‐1 and LAG‐3 inhibitors in ...
Tine J. Monberg, Cathrine L. Lorentzen, Marie C. W. Westergaard, Trine Z. Iversen, Troels H. Borch, Marco Donia, Sigrid M. Mannering, Stine E. W. Banke, Özcan Met, Inge Marie Svane   +9 more
wiley   +1 more source

Maternal Thyroid Diseases, Medication Use and Childhood Cancer Risks in Offspring: A Population‐Based Cohort Study in Denmark

International Journal of Cancer, EarlyView.
Thyroid diseases are common among women of reproductive age and may be related to childhood cancer, but the evidence is inconsistent. This study of childhood cancer with maternal thyroid diseases and medication use in a population‐based case‐control study using Danish registries found positive associations between maternal goiter and overall cancer ...
Chuanjie Deng, Kosuke Inoue, Chai Saechao, Johnni Hansen, Beate Ritz, Julia E. Heck   +5 more
wiley   +1 more source

What Endocrinologists Should Know About Iodine: Population Deficiency, Individual Excess and Misinformation in the United Kingdom

Clinical Endocrinology, EarlyView.
ABSTRACT Iodine deficiency, once considered eliminated in the United Kingdom, has re‐emerged, particularly among women of reproductive age, in whom requirements are increased during pregnancy and lactation. The declining consumption of dairy and white fish, the emerging use of unfortified plant‐based milk alternatives, and the absence of a national ...
Peter N. Taylor, Malcolm Prentice, Sarah Bath, Emilie Combet, Nadia Schoenmakers, Vicki E. Smith, Fraser W. Gibb, Nicola Zammitt, Onyebuchi Okosieme, Kristien Boelaert, John Lazarus, Mark Vanderpump   +11 more
wiley   +1 more source

Amiodarone‐related thyroid dysfunction and associated outcomes in patients with heart failure—A nationwide cohort study

Journal of Internal Medicine, EarlyView.
Abstract Aim Amiodarone increases the risk of thyroid dysfunction, but the prognostic significance of this complication in patients with heart failure (HF) is uncertain. This study investigates the association between amiodarone‐related thyroid dysfunction and risk of HF hospitalization or death in a nationwide cohort.
Søren Lund Kristensen, Sam Aiyad Ali, Mads Ersbøll, Jawad Haider Butt, Rasmus Rørth, Lucas Malta Westergaard, Lauge Østergaard, Finn Gustafsson, Oren Caspi, Emil Fosbøl, Lars Køber, Christian Selmer   +11 more
wiley   +1 more source

Effects of the Antithyroid Agent Propylthiouracil in a Partial Life Cycle Assay with Zebrafish [PDF]

Environmental Science & Technology, 2005
Some ubiquitous pollutants of the aquatic environment, such as PCBs or other polyhalogenated aromatic hydrocarbons, may disrupt the thyroid hormone system. In a partial life cycle assay with zebrafish (Danio rerio), we studied the effects of the reference compound propylthiouracil (PTU) on reproduction, growth and development, histopathology of some ...
Van der Ven, Leo, Van den Brandhof, Evert-Jan, Vos, José H., Power, Deborah, Wester, Piet W.   +4 more
openaire   +4 more sources

Thyrotoxic Periodic Paralysis—A Misleading Challenge in the Emergency Department

Diagnostics, 2020
Despite its’ life-threatening potential due to cardiac severe dysrhythmia in the context of severe hypokalemia, thyrotoxic periodic paralysis (TPP) often goes unrecognized.
Stefana Bilha, Ovidiu Mitu, Laura Teodoriu, Cristian Haba, Cristina Preda   +4 more
doaj   +1 more source

Graves' Disease: Can It Be Cured? [PDF]

Endocrinology and Metabolism, 2019
Whether or not Graves' hyperthyroidism can be really cured, depends on the definition of “cure.” If eradication of thyroid hormone excess suffices for the label “cure,” then all patients can be cured because total thyroidectomy or high doses of 131I will
Wilmar M. Wiersinga
doaj   +1 more source

Feline diabetes. Part 2: monitoring and management with other diseases

In Practice, Volume 48, Issue 5, Page 228-241, June 2026.
Background: Diabetes mellitus (DM) in cats is commonly seen in primary care practice and presents several clinical and practical challenges to owners and vets. In recent years feline DM has seen paradigm shifts in management and monitoring. Aim of the article: In this second article of a series on feline DM, we look at the monitoring options that are ...
Ian Ramsey, Anna Kraemer
wiley   +1 more source

Synthesis and Characterization of Sulfonamide‐Schiff Bases, and Investigation of Cytotoxic, Antioxidant, HDAC, and Apoptotic Activities in Human Colon Cancer Cells (DLD‐1 and HT‐29)

Archiv der Pharmazie, Volume 359, Issue 4, April 2026.
New sulfonamide‐Schiff bases were synthesized, characterized, and investigated for their cytotoxic, antioxidant, HDAC, and apoptotic activities in human colon cancer cells (DLD‐1 and HT‐29). Compounds 3c and 3d emerged as promising candidates to act as selective therapeutic agents by targeting the p38/MAPK‐ERK1 pathway in colorectal cancer.
Seda Mesci, Berna Kocaman, Aliye Gediz Erturk, Emine Bagdatli, Burak Yazgan, Tuba Yildirim   +5 more
wiley   +1 more source

Henoch–Schönlein Purpura (IgA Vasculitis) in Association with Thyrotoxicosis

Case Reports in Endocrinology, 2021
Graves’ disease is the most common cause of hyperthyroidism, which is characterized by thyroid antibodies and the following clinical manifestations: goiter, ophthalmopathy, and pretibial myxedema.
Mojgan Sanjari, Mohammadreza Shakibi, Moeinadin Safavi   +2 more
doaj   +1 more source