Results 51 to 60 of about 6,442 (232)

Hashimoto encephalopathy: Neurological and psychiatric perspective [PDF]

open access: yes, 2009
Hashimoto encephalopathy (HE) is an autoimmune disease with neurological and neuropsychiatric manifestations and elevated titers of antithyroid antibodies in serum and cerebrospinal fluid. Patients are mostly women.
Lačković Maja   +2 more
core   +1 more source

Enhancement of Paclitaxel's Anticancer Efficacy in Thyroid Cancer by Isodeoxyelephantopin Through Modulation of Oxidative Stress

open access: yesFood Science &Nutrition, Volume 13, Issue 12, December 2025.
Isodeoxyelephantopin (IDET) enhances paclitaxel sensitivity in thyroid cancer by promoting ROS‐mediated apoptosis through inhibition of the p62‐Keap1‐Nrf2 antioxidant pathway. The combination treatment suppresses tumor growth and metastasis with minimal toxicity, suggesting IDET as a safe and effective chemosensitizer to improve Taxol‐based therapy ...
Wei Cong   +3 more
wiley   +1 more source

Cholestatic jaundice caused by sequential carbimazole and propylthiouracil treatment for thyrotoxicosis [PDF]

open access: yes, 2003
A 36-year-old Chinese man presented to the Queen Mary Hospital in August 1999 with a 2-week history of jaundice due to propylthiouracil treatment for thyrotoxicosis. He had previously received carbimazole but had developed an urticarial skin rash after 2
Chan, AOO   +4 more
core  

Thyroid Cancer: Pathogenesis, Clinicopathology, Diagnosis, and Management

open access: yesMedComm, Volume 6, Issue 11, November 2025.
Thyroid cancer risk is influenced by both genetic and modifiable factors, including mutations, radiation exposure, lifestyle, and pre‐existing benign conditions. Diagnosis involves physical exams, ultrasound, scintigraphy, laboratory tests, and fine‐needle aspiration biopsy (FNAB).
Yu‐Dong Li   +3 more
wiley   +1 more source

Mechanism of the Inhibition of Enzymatic Halogenation by Antithyroid Agents

open access: yesJournal of Biological Chemistry, 1966
Abstract Antithyroid agents of the thiourea type (thiourea, thiouracil, and 5-vinyl-2-oxazolidinethione) inhibit the enzymatic halogenation reactions catalyzed by chloroperoxidase. These compounds are competitive with the halogen acceptor molecule and serve as substrates for chloroperoxidase. These antithyroid agents are oxidized by chloroperoxidase in
D R, Morris, L P, Hager
openaire   +2 more sources

Carbimazole induced agranulocytosis with life-threatening complications, tremendous response with granulocyte-colony stimulating factor

open access: yesMedical Journal of Dr. D.Y. Patil University, 2016
Agranulocytosis is a rare complication of drug carbimazole (0.23%). We are accounting to present a very interesting and rare case of agranulocytosis and neutropenic sepsis secondary to carbimazole that have tremendous response with recombinant human ...
Seema Mahant   +2 more
doaj   +1 more source

Managing thyroid dysfunction in selected special situations [PDF]

open access: yes, 2013
Managing thyroid dysfunction is simple at first glance, the idea is to bring hormone levels in the euthyroid range, treat with antithyroid drugs, radio-iodine or surgery if toxic and replace with thyroxine or T3 if hypothyroid.
Durr e Sabih, Mohammad Inayatullah
core   +1 more source

Silent Dangers in Elderly Pharmacotherapy: The Interplay of Polypharmacy, Multimorbidity, and Drug Interactions

open access: yesJournal of Evaluation in Clinical Practice, Volume 31, Issue 7, October 2025.
ABSTRACT Background Pharmacological therapy in older persons is inherently complex due to the interplay of age‐related physiological changes, multimorbidity, and polypharmacy. These factors increase the vulnerability of elderly patients to drug interactions and adverse drug reactions.
N. N. Ngcobo
wiley   +1 more source

Does choice of therapy save costs and improve outcomes in hyperthyroid patients [PDF]

open access: yes, 2008
OBJECTIVE: To compare cost of treating hyperthyroidism with antithyroid medications (ATD) versus radioactive iodine (RAI). As secondary outcome we also analyzed data in terms of remission rates.
Akhter, J.   +4 more
core   +1 more source

A Scoping Review of Human Teratogens and Their Impact on the Developing Brain: A Contribution From the ConcePTION Project

open access: yesBirth Defects Research, Volume 117, Issue 9, September 2025.
ABSTRACT Certain medications, when used during pregnancy, are known to impact human prenatal development. Historically, little attention has been given to the impact of in utero exposure on the developing brain, despite the significance of known teratogen‐induced neurodevelopmental difficulties.
M. Bluett‐Duncan   +14 more
wiley   +1 more source

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