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Iodide for the management of Graves' disease in pregnancy. [PDF]
Yoshihara A, Noh JY, Watanabe N, Ito K.
europepmc +1 more source
Predictors of Treatment Outcomes in Pediatric Graves' Disease. [PDF]
Shin DY +4 more
europepmc +1 more source
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The Origin of Antithyroid Drugs
Thyroid, 2023Background: When the antithyroid drugs were discovered in the early 1940s, they were immediately recognized as a revolutionary new treatment for hyperthyroidism. Although much has been learned about their mechanism of action and clinical utility, they continue to be used today in much the same way as they have ...
Clark T Sawin
exaly +3 more sources
Antithyroid Drugs and their Analogues Protect Against Peroxynitrite‐Mediated Protein Tyrosine Nitration—A Mechanistic Study [PDF]
In this paper, the effect of some commonly used antithyroid drugs and their analogues on peroxynitrite-mediated nitration of proteins is described. The nitration of tyrosine residues in bovine serum albumin (BSA) and cytochrome c was studied by Western ...
Krishna Pada Bhabak
exaly +4 more sources
Thiouracil Antithyroid Drugs as a New Class of Neuronal Nitric Oxide Synthase Inhibitors [PDF]
Two established antithyroid drugs, 6-propyl-2-thiouracil and 6-methyl-2-thiouracil, as well as S-methylthiouracil, are shown to be competitive inhibitors of nitric oxide synthase (NOS) (K-1 values ranging from 14 to 60 muM), with moderate selectivity for
Anna Palumbo, Marco D'Ischia
exaly +2 more sources

