Results 71 to 80 of about 12,171 (216)

A Study on Nonthermal Irreversible Electroporation of the Thyroid. [PDF]

, 2019
BackgroundNonthermal irreversible electroporation is a minimally invasive surgery technology that employs high and brief electric fields to ablate undesirable tissues.
Huang, Jianwei, Lv, Yanpeng, Rubinsky, Boris, Wang, Yunlong, Zhang, Yanfang   +4 more
core  

RESULTS OF LONG-TERM FOLLOW-UP AFTER COMPENSATED FIXED-DOSE THERAPY FOR THYROTOXICOSIS [PDF]

, 1992
To evaluate the effects of simple compensated fixed-dose iodine-131 therapy for thyrotoxicosis, the long-term results for 74 patients treated with a fixed dose of iodine-131 ranging from 5 to 12 mCi (185 to 444 MBq) were evaluated in the first 2 years of
CHAN, SP, DOI, SAR, KHIR, A, KHOO, BH, PARAMSOTHY, M, ZAINI, A   +5 more
core   +1 more source

TSHR‐Targeting Nucleic Acid Aptamer Treats Graves' Ophthalmopathy via Novel Allosteric Inhibition

Advanced Science, Volume 13, Issue 4, 19 January 2026.
This study presents YC3, a novel inhibitory TSHR‐targeting aptamer, as a promising therapeutic for Graves' ophthalmopathy (GO). YC3 suppresses pathological phenotypes in human orbital fibroblasts and improves outcomes in GO mice by binding to a previously unidentified allosteric site on TSHR, demonstrating the potential of aptamers in advancing ...
Yanchen Zhang, Ende Wu, Weibin Liu, Ling Zeng, Neng Ling, Hongmei Wang, Zhixing Li, Shuang Yao, Tonghe Pan, Xuanwen Li, Yate Huang, Xiaojing Li, Yunhai Tu, Wentao Yan, Jianzhang Wu, Mao Ye, Wencan Wu   +16 more
wiley   +1 more source

Projected reduction in healthcare costs in Belgium after optimization of iodine intake : impact on costs related to thyroid nodular disease [PDF]

, 2010
Background: Several surveys in the last 50 years have repeatedly indicated that Belgium is affected by mild iodine deficiency. Within the framework of the national food and health plan in Belgium, a selective, progressive, and monitored strategy was ...
Annemans, Lieven, Moreno-Reyes, Rodrigo, Tafforeau, Jean, Van Oyen, Herman, Vandevijvere, Stefanie   +4 more
core   +1 more source

Antithyroid Drug Treatment in Pregnancy [PDF]

The Journal of Clinical Endocrinology & Metabolism, 2012
Antithyroid (thionamide) drugs, discovered after the work of the Mackenzies (1) and introduced into clinical medicine by Astwood and colleagues, have been in widespread use for the treatment of thyrotoxicosis for nearly 70 yr (2). The drugs methimazole (MMI), carbimazole (CBZ), the prodrug of MMI, and propylthiouracil (PTU) have been administered to ...
openaire   +2 more sources

Single‐Cell RNA Sequencing of Thyroid Tissues Reveals Pathogenesis of Graves' Disease

Advanced Science, Volume 13, Issue 1, 5 January 2026.
Using single‐cell RNA sequencing and TCR profiling, this study constructed an immune cell atlas in thyroid tissue of Graves’ disease (GD), revealing dominant IFN‐γ‐secreting CD4+ T cells, expanded Tph and CD11c+ B cells, and enriched T/NK cells. Notably, GD thyroid follicular cells (TFCs) activated γδ T cells, which recruited cDC1 cells, suggesting a ...
Xiaoyi Zhou, Jia Cong, Rongguang Peng, Dichen Yang, Chenchen Dong, Jing Xie, Jiqi Yan, Jie Kuang, Fubin Li, Leng Siew Yeap, Xiaoyan Xie, Haolong Yin, Rulai Han, Liyun Shen, Yulin Zhou, Guang Ning, Shu Wang, Weiqing Wang, Lei Ye   +18 more
wiley   +1 more source

MANAGEMENT OF HYPERTHYROIDISM IN CHILDREN AND ADOLESCENTS – TEN YEARS EXPERIENCE

Zdravniški Vestnik, 2003
Background. Graves disease is the most common cause of hyperthyrosis in children and adolescents. The optimal treatment for children with AH remains controversial.
Nevenka Bratanič, Marjeta Maroša-Meolic, Nives Hočevar, Mojca Žerjav-Tanšek, Nataša Uršič-Bratina, Ciril Kržišnik, Tadej Battelino   +6 more
doaj  

Clinical Characteristics of Patients With Overdose Engaging in Nonmedical Use of Prescription Drugs: A Single‐Center Study in Japan

Acute Medicine &Surgery, Volume 13, Issue 1, January/December 2026.
In a Japanese emergency department, 7.9% of overdose cases involved nonmedical use of prescription drugs, primarily obtained from family or friends. NMUPD cases more often featured alcohol coingestion and limited psychiatric engagement and involved multiple commonly prescribed psychotropic drug classes rather than a single class.
Nobuki Shioya, Nozomu Inoue, Takahiro Nishitani, Naonori Kawashima, Yuki Tsukamoto, Tomohiro Sato, Yoshihiro Sadamoto, Yuki Naito, Kohji Hazama, Yasuo Shichinohe   +9 more
wiley   +1 more source

Differential diagnosis and treatment of thyroid storm [PDF]

Zhenduanxue lilun yu shijian
Thyroid storm is a rare, life-threatening endocrine emergency characterized by severe clinical manifestations of thyrotoxicosis. Studies in the United States and Japan show that the annual incidence rates of hyperthyroid storm are (0.57-0.76) per 100 000
YAN Huixian, LÜ Chaohui
doaj   +1 more source

Life‐Threatening Agranulocytosis Induced by Sinomenine Hydrochloride in Chronic Kidney Disease: A Case Report and Literature Review

Clinical Case Reports, Volume 14, Issue 1, January 2026.
ABSTRACT Sinomenine, derived from Sinomenium acutum, is widely used in inflammatory diseases. However, its risk of inducing agranulocytosis is not widely appreciated. We report a life‐threatening case in a 40‐year‐old woman with chronic kidney disease (CKD; baseline estimated glomerular filtration rate [eGFR] as low as 36 mL/min/1.73 m2) who developed ...
Ping Xin, Ruoyan Liu, Yu Zhang, Bin Fu
wiley   +1 more source