Results 11 to 20 of about 1,053 (146)
Dynamics-Based Regulatory Switches of Type II Antitoxins: Insights into New Antimicrobial Discovery
Antibiotics, 2023 Type II toxin-antitoxin (TA) modules are prevalent in prokaryotes and are involved in cell maintenance and survival under harsh environmental conditions, including nutrient deficiency, antibiotic treatment, and human immune responses. Typically, the type
Bong-Jin Lee
exaly +4 more sources
sRNA Antitoxins: More than One Way to Repress a Toxin
Toxins, 2014 Bacterial toxin-antitoxin loci consist of two genes: one encodes a potentially toxic protein, and the second, an antitoxin to repress its function or expression. The antitoxin can either be an RNA or a protein.
Jia Wen, Elizabeth M. Fozo
doaj +2 more sources
Evaluating the Potential for Cross-Interactions of Antitoxins in Type II TA Systems
Toxins, 2020 The diversity of Type-II toxin–antitoxin (TA) systems in bacterial genomes requires tightly controlled interaction specificity to ensure protection of the cell, and potentially to limit cross-talk between toxin–antitoxin pairs of the same family of TA ...
Chih-Han Tu +3 more
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JAMA: The Journal of the American Medical Association, 1898 n ...
Houghton, E. Mark, E. MARK HOUGHTON
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Evolution of the SpoIISABC Toxin-Antitoxin-Antitoxin System in Bacilli [PDF]
Toxins, 2016 Programmed cell death in bacteria is generally associated with two-component toxin-antitoxin systems. The SpoIISABC system, originally identified in Bacillus subtilis, consists of three components: a SpoIISA toxin and the SpoIISB and SpoIISC antitoxins ...
Marek Gabriško, Imrich Barák
doaj +3 more sources
Keeping the wolves at bay: antitoxins of prokaryotic type II toxin-antitoxin systems [PDF]
Frontiers in Molecular Biosciences, 2016 In their initial stages of discovery, prokaryotic toxin-antitoxin (TA) systems were confined to bacterial plasmids where they function to mediate the maintenance and stability of usually low- to medium-copy number plasmids through the post-segregational ...
Wai Ting eChan +2 more
doaj +4 more sources
Large-Scale Comparison of Toxin and Antitoxins in Listeria monocytogenes [PDF]
Toxins, 2020 Toxin−antitoxin systems (TASs) are widely distributed in prokaryotes and encode pairs of genes involved in many bacterial biological processes and mechanisms, including pathogenesis.
José Antonio Agüero +4 more
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mSystemsBacterial chromosomal type I toxin-antitoxin systems consist of a small protein, typically under 60 amino acids, and a small RNA (sRNA) that represses toxin translation.
Selene F. H. Shore +3 more
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EFFECT OF ANAEROBIC PROBIOTIC AND/OR BIOLOGICAL ANTITOXIN SUPPLEMENTATIONS ON PRODUCTIVE AND REPRODUCTIVE PERFORMANCE OF LACTATING COWS [PDF]
Arab Universities Journal of Agricultural Sciences, 2019 Forty-eight lactating Holstein Friesian cows were utilized to assess impact of supplementing probiotic ZAD (mixture of live bacterial cells and enzymes) compared with T5X (antitoxins product) on some productive, reproductive and antitoxins activity ...
M. Kholif +4 more
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Induced DNA bending by unique dimerization of HigA antitoxin
IUCrJ, 2020 The bacterial toxin–antitoxin (TA) system regulates cell growth under various environmental stresses. Mycobacterium tuberculosis, the causative pathogen of tuberculosis (TB), has three HigBA type II TA systems with reverse gene organization, consisting ...
Jin-Young Park +6 more
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