Results 31 to 40 of about 1,053 (146)

Pharmacokinetics of Human Recombinant Anti-Botulinum Toxin Antibodies in Rats

open access: yesToxins, 2019
Botulinum neurotoxins (BoNT) are potential biothreat agents due to their high lethality, potency, and ease of distribution, thus the development of antitoxins is a high priority to the US government.
Yero Espinoza   +9 more
doaj   +1 more source

VapC Toxins from Mycobacterium tuberculosis are ribonucleases that differentially inhibit growth and are neutralized by cognate VapB antitoxins [PDF]

open access: yes, 2011
The chromosome of Mycobacterium tuberculosis (Mtb) encodes forty seven toxin-antitoxin modules belonging to the VapBC family. The role of these modules in the physiology of Mtb and the function(s) served by their expansion are unknown.
Mizrahi, Valerie   +36 more
core   +2 more sources

Prokaryotic toxin-antitoxins

open access: yes, 2013
\ua9 2013 Springer-Verlag Berlin Heidelberg. All rights reserved. Prokaryotic Toxins - Antitoxins gives the first overview of an exciting and rapidly expanding research field. Toxin - antitoxin (TA) genes were discovered on plasmids 30 years ago.
Gerdes K
core   +4 more sources

Algal chloroplast produced camelid VHH antitoxins are capable of neutralizing botulinum neurotoxin [PDF]

open access: yes, 2015
We have produced three antitoxins consisting of the variable domains of camelid heavy chain-only antibodies (VH H) by expressing the genes in the chloroplast of green algae.
Shoemaker, Charles B   +9 more
core   +1 more source

Toxin-Antitoxin Systems as Multilevel Interaction Systems

open access: yesToxins, 2014
Toxin-antitoxin (TA) systems are small genetic modules usually composed of a toxin and an antitoxin counteracting the activity of the toxic protein. These systems are widely spread in bacterial and archaeal genomes.
Nathalie Goeders, Laurence Van Melderen
doaj   +1 more source

Toxin-Antitoxin Systems of Staphylococcus aureus

open access: yesToxins, 2016
Toxin-antitoxin (TA) systems are small genetic elements found in the majority of prokaryotes. They encode toxin proteins that interfere with vital cellular functions and are counteracted by antitoxins.
Christopher F. Schuster, Ralph Bertram
doaj   +1 more source

Antitoxin. [PDF]

open access: yesJAMA: The Journal of the American Medical Association, 1895
n ...
  +6 more sources

Bacterial Toxin-Antitoxin Systems’ Cross-Interactions—Implications for Practical Use in Medicine and Biotechnology

open access: yesToxins, 2023
Toxin-antitoxin (TA) systems are widely present in bacterial genomes. They consist of stable toxins and unstable antitoxins that are classified into distinct groups based on their structure and biological activity. TA systems are mostly related to mobile
Lidia Boss, Barbara Kędzierska
doaj   +1 more source

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