Results 51 to 60 of about 6,014 (171)
The presence of botulinum neurotoxin-producing Clostridia (BPC) in food sources is a public health concern. In favorable environmental conditions, BPC can produce botulinum neurotoxins (BoNTs) outside or inside the vertebrate host, leading to ...
Luca Bano +7 more
doaj +1 more source
Oral Phageome as Potential Modulators of Periodontal Dysbiosis. A Systematic Review
ABSTRACT Introduction The oral phageome, comprising bacteriophages inhabiting the oral cavity, has been proposed as a potential modulator of periodontal health and disease. This systematic review synthesizes current evidence on interactions between bacteriophages, key periodontal bacteria, and the host in periodontitis.
Marco Bonilla +3 more
wiley +1 more source
Persistence is a transient and non-inheritable tolerance to antibiotics by a small fraction of a bacterial population. One of the proposed determinants of bacterial persistence is toxin-antitoxin systems (TAS) which are also implicated in a wide range of
Bhaskar Chandra Mohan Ramisetty +4 more
doaj +1 more source
Summary: Botulinum neurotoxin (BoNT) is one of the most acutely lethal toxins known to humans, and effective treatment for BoNT intoxication is urgently needed.
Kwok-ho Lam +8 more
doaj +1 more source
Summary Arbuscular mycorrhizal fungi (AMF) are widespread plant symbionts that enhance nutrient acquisition and influence ecosystem productivity. Previous chromosome‐level assemblies of the model species Rhizophagus irregularis revealed a two‐compartment genome architecture (active A and repressed B chromatin compartments), yet its conservation across ...
Ken Mugambi +10 more
wiley +1 more source
Temporins, among antimicrobial peptides, are short frog‐derived molecules with potent antibacterial activity. This review highlights chemical optimization strategies applied to temporins A–L, showing how sequence tuning modulates structure, stability, and selectivity, enabling improved activity against resistant pathogens.
Ida Boccino +2 more
wiley +1 more source
Toxins, Pathogenicity, Anti-Toxins, a Bicentennial Contribution
The bicentenary of Louis Pasteur’s birth raises the opportunity to revisit the activity and influence of L [...]
Michel R. Popoff, Daniel Ladant
doaj +1 more source
Recent Advances in the Molecular Mechanisms of Bacterial Anti‐Phage Defence Systems
Panoptes as an example for an antiphage system consists of OptS producing a cyclic dinucleotide that prevents activation of OptE, a transmembrane protein. Phage T4 infection introduces the sponge protein Acb2 that adsorbs the cyclic dinucleotide thus activating OptE which disrupts the cell membrane aborting phage infection.
Harald Brüssow
wiley +1 more source
Development of an Innovative in Vitro Potency Assay for Anti-Botulinum Antitoxins
Botulinum neurotoxins are bacterial proteins that cause botulism, a life-threatening disease. Therapy relies mostly on post-intoxication antibody treatment. The only accepted method to measure the potency of, and to approve, antitoxin preparations is the
Osnat Rosen +4 more
doaj +1 more source

