Results 41 to 50 of about 7,132 (197)

COUNTER IMMUNO ELECTROPHORESIS AS RAPID AND counter TIVE TEST IN DETECTION OF BETA AND EPSILON OF CL. PERFRINGENS TYPES B AND IN COMPARISON WITH ELISA AND MOUSE PROTECTION TEST [PDF]

open access: yesVeterinary Medical Journal - Giza, 2000
Cancer mmunoelectrophoresis ( CIEP ) assay sed as quantitative method for detection of epsilin and Beta antitoxins in sera of vaccinated goats as compared with indirect enzyme linked unosorbent assay ( ELISA )in vitro and in  Mouse protection test (SNT).
M MAKHARETA, ELHAM EL-EBIARY
doaj   +1 more source

WHAT ARE ANTITOXINS? [PDF]

open access: yesJAMA: The Journal of the American Medical Association, 1899
In a lecture delivered by Dr. T. Clifford Allbutt, regius professor of physics in Cambridge University, England, before the Johns Hopkins University in October, 1898, occur these words 1 : "The study of origins, then, is not only the new method of modern criticism, of modern history, of modern anthropology, of our reading of the evolution of the ...
openaire   +2 more sources

Structural Basis of Shiga Toxin Neutralization by Human Antibodies Targeting Canonical Receptor‐Binding and Non‐Canonical Assembly Sites

open access: yesAdvanced Science, EarlyView.
Cryo‐electron microscopy structures reveal two distinct neutralization mechanisms of fully human monoclonal antibodies targeting the Shiga toxin 1a B subunit. RDS059 occludes the Gb3 receptor‐binding site, whereas RDS045 engages a lateral quaternary epitope to disrupt holotoxin assembly.
Jianting Ke   +10 more
wiley   +1 more source

Neutralization of Tetanus Neurotoxin with Various Botulinum Antitoxins (A-F) in a Study to Isolate Clostridium botulinum from Field Samples

open access: yes, 2010
In a study to isolate Clostridium botulinum from field samples, 53 C. botulinum-like isolates were found neutralizable by botulinum antitoxins using the standard mouse bioassay.
Bohnel, H.   +2 more
core   +2 more sources

Toxinome—the bacterial protein toxin database

open access: yesmBio
Protein toxins are key molecular weapons in biology that are used to attack neighboring cells. Bacteria use protein toxins to kill or inhibit the growth of prokaryotic and eukaryotic cells using various modes of action that target essential cellular ...
Aleks Danov   +6 more
doaj   +1 more source

The Collective Power of Bacteria as a Blueprint for Emergent Intelligence

open access: yesAdvanced Intelligent Systems, EarlyView.
Small cells, powerful collectives. Bacteria demonstrate how sophisticated behaviors can emerge from many simple individuals working together. We explore the remarkable world of bacterial communities and the mechanisms that underpin their complex emergent behaviors, enabling impressive adaptability, robustness, and responsiveness to changing ...
Johanna A. Blee   +2 more
wiley   +1 more source

SiMa Cells for a Serotype Specific and Sensitive Cell-Based Neutralization Test for Botulinum Toxin A and E

open access: yesToxins, 2017
Botulinum toxins (BoNTs), of which there are seven serotypes, are among the most potent neurotoxins, with serotypes A, B and E causing human botulism.
Nicola Bak   +3 more
doaj   +1 more source

Diphtheritic myocarditis: A case series and review of literature

open access: yesJournal of Family Medicine and Primary Care, 2020
Myocarditis in patients with diphtheria is a toxin-mediated complication that sets in after one week of onset of respiratory illness. Early administration of antidiphtheritic serum in patients with clinical diphtheria before the onset of myocarditis is ...
Sonali Singh, Nitin Gupta, Pallavi Saple
doaj   +1 more source

Phase I Evaluation of Siltartoxatug, a First‐in‐Class Anti‐Tetanus Monoclonal Antibody: Safety, Pharmacokinetics and Pharmacodynamics in Healthy Australian and Chinese Populations

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Siltartoxatug, a first‐in‐class monoclonal antibody targeting tetanus toxin for post‐exposure prophylaxis, was evaluated in two phase I trials in Australian and Chinese healthy adults. In these randomized, double‐blind, placebo‐controlled, dose‐escalation studies, participants received a single intramuscular injection of siltartoxatug (10–250 μg/kg) or
Xinyu Liu   +15 more
wiley   +1 more source

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