Results 21 to 30 of about 7,132 (197)
Heterologous expression of different candidate toxins and antitoxins in E. coli.
, 2021 Immunoblot analysis of E. coli expressing heterologous candidate toxins and antitoxins cloned into the pBAD/His expression vector. Expression was induced by addition of arabinose and monitored during 7 hours.
Martin Heller (168038) +10 more
core +1 more source
Three dimensional structure of the MqsR:MqsA complex: a novel TA pair comprised of a toxin homologous to RelE and an antitoxin with unique properties. [PDF]
PLoS Pathogens, 2009 One mechanism by which bacteria survive environmental stress is through the formation of bacterial persisters, a sub-population of genetically identical quiescent cells that exhibit multidrug tolerance and are highly enriched in bacterial toxins ...
Breann L Brown +7 more
doaj +1 more source
mBio, 2022 Small alarmone hydrolases (SAHs) are alarmone metabolizing enzymes found in both metazoans and bacteria. In metazoans, the SAH homolog Mesh1 is reported to function in cofactor metabolism by hydrolyzing NADPH to NADH.
Danny K. Fung +7 more
doaj +1 more source
Toxin-Antitoxin Systems as Multilevel Interaction Systems
Toxins, 2014 Toxin-antitoxin (TA) systems are small genetic modules usually composed of a toxin and an antitoxin counteracting the activity of the toxic protein. These systems are widely spread in bacterial and archaeal genomes.
Nathalie Goeders, Laurence Van Melderen
doaj +1 more source
Toxin-antitoxin system promoter binding by type IV antitoxins of Mycobacterium tuberculosis [PDF]
, 2019 Tuberculosis remains a global health concern that requires difficult and lengthy treatment regimens for latent and persistent infection. Toxin-antitoxin systems have been linked to controlling bacterial growth rate and also implicated in bacterial ...
Beck, Izaak Nathan
core +3 more sources
Toxin-Antitoxin Systems of Staphylococcus aureus
Toxins, 2016 Toxin-antitoxin (TA) systems are small genetic elements found in the majority of prokaryotes. They encode toxin proteins that interfere with vital cellular functions and are counteracted by antitoxins.
Christopher F. Schuster, Ralph Bertram
doaj +1 more source
Algal chloroplast produced camelid VHH antitoxins are capable of neutralizing botulinum neurotoxin [PDF]
, 2015 We have produced three antitoxins consisting of the variable domains of camelid heavy chain-only antibodies (VH H) by expressing the genes in the chloroplast of green algae.
Shoemaker, Charles B +9 more
core +1 more source