Results 21 to 30 of about 1,053 (146)
Stay or Go: Sulfolobales Biofilm Dispersal Is Dependent on a Bifunctional VapB Antitoxin
mBio, 2023 A type II VapB14 antitoxin regulates biofilm dispersal in the archaeal thermoacidophile Sulfolobus acidocaldarius through traditional toxin neutralization but also through noncanonical transcriptional regulation.
April M. Lewis +5 more
doaj +1 more source
Clinical cases of atypical and severe botulism
Zaporožskij Medicinskij Žurnal, 2020 The aim of the work was to present two clinical cases of botulism: the atypical course and the severe course with late administration of heptavalent botulinum antitoxin, which still had a significant positive clinical effect and contributed to a faster ...
O. L. Ivakhiv, N. Yu. Vyshnevska
doaj +1 more source
Toxin-antitoxin system promoter binding by type IV antitoxins of Mycobacterium tuberculosis [PDF]
, 2019 Tuberculosis remains a global health concern that requires difficult and lengthy treatment regimens for latent and persistent infection. Toxin-antitoxin systems have been linked to controlling bacterial growth rate and also implicated in bacterial ...
Beck, Izaak Nathan
core +6 more sources
Recent genomic analyses revealed a surprisingly large number of toxin-antitoxin loci in free-living prokaryotes. The antitoxins are proteins or antisense RNAs that counteract the toxins.
Gerdes K, Wagner EGH
core +5 more sources
Humoral Response of Buffaloes to a Recombinant Vaccine against Botulism Serotypes C and D
Toxins, 2017 Botulism is a fatal intoxication caused by botulinum neurotoxins (BoNTs), which are mainly produced by Clostridium botulinum and characterized by flaccid paralysis.
Denis Y. Otaka +9 more
doaj +1 more source
Treatments for Pulmonary Ricin Intoxication: Current Aspects and Future Prospects
Toxins, 2017 Ricin, a plant-derived toxin originating from the seeds of Ricinus communis (castor beans), is one of the most lethal toxins known, particularly if inhaled.
Yoav Gal +5 more
doaj +1 more source
Questionable Efficacy of Therapeutic Antibodies in the Treatment of Anthrax
mSphere, 2019 Inhalational anthrax caused by Bacillus anthracis, a spore-forming Gram-positive bacterium, is a highly lethal infection. Antibodies targeting the protective antigen (PA) binding component of the toxins have recently been authorized as an adjunct to ...
Jean-Nicolas Tournier +3 more
doaj +1 more source
Three dimensional structure of the MqsR:MqsA complex: a novel TA pair comprised of a toxin homologous to RelE and an antitoxin with unique properties. [PDF]
PLoS Pathogens, 2009 One mechanism by which bacteria survive environmental stress is through the formation of bacterial persisters, a sub-population of genetically identical quiescent cells that exhibit multidrug tolerance and are highly enriched in bacterial toxins ...
Breann L Brown +7 more
doaj +1 more source
mBio, 2022 Small alarmone hydrolases (SAHs) are alarmone metabolizing enzymes found in both metazoans and bacteria. In metazoans, the SAH homolog Mesh1 is reported to function in cofactor metabolism by hydrolyzing NADPH to NADH.
Danny K. Fung +7 more
doaj +1 more source