Results 21 to 30 of about 6,597 (200)
Clinical cases of atypical and severe botulism
Zaporožskij Medicinskij Žurnal, 2020 The aim of the work was to present two clinical cases of botulism: the atypical course and the severe course with late administration of heptavalent botulinum antitoxin, which still had a significant positive clinical effect and contributed to a faster ...
O. L. Ivakhiv, N. Yu. Vyshnevska
doaj +1 more source
Humoral Response of Buffaloes to a Recombinant Vaccine against Botulism Serotypes C and D
Toxins, 2017 Botulism is a fatal intoxication caused by botulinum neurotoxins (BoNTs), which are mainly produced by Clostridium botulinum and characterized by flaccid paralysis.
Denis Y. Otaka +9 more
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Treatments for Pulmonary Ricin Intoxication: Current Aspects and Future Prospects
Toxins, 2017 Ricin, a plant-derived toxin originating from the seeds of Ricinus communis (castor beans), is one of the most lethal toxins known, particularly if inhaled.
Yoav Gal +5 more
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Questionable Efficacy of Therapeutic Antibodies in the Treatment of Anthrax
mSphere, 2019 Inhalational anthrax caused by Bacillus anthracis, a spore-forming Gram-positive bacterium, is a highly lethal infection. Antibodies targeting the protective antigen (PA) binding component of the toxins have recently been authorized as an adjunct to ...
Jean-Nicolas Tournier +3 more
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Heterologous expression of different candidate toxins and antitoxins in E. coli.
, 2021 Immunoblot analysis of E. coli expressing heterologous candidate toxins and antitoxins cloned into the pBAD/His expression vector. Expression was induced by addition of arabinose and monitored during 7 hours.
Martin Heller (168038) +10 more
core +1 more source
Three dimensional structure of the MqsR:MqsA complex: a novel TA pair comprised of a toxin homologous to RelE and an antitoxin with unique properties. [PDF]
PLoS Pathogens, 2009 One mechanism by which bacteria survive environmental stress is through the formation of bacterial persisters, a sub-population of genetically identical quiescent cells that exhibit multidrug tolerance and are highly enriched in bacterial toxins ...
Breann L Brown +7 more
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mBio, 2022 Small alarmone hydrolases (SAHs) are alarmone metabolizing enzymes found in both metazoans and bacteria. In metazoans, the SAH homolog Mesh1 is reported to function in cofactor metabolism by hydrolyzing NADPH to NADH.
Danny K. Fung +7 more
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Pharmacokinetics of Human Recombinant Anti-Botulinum Toxin Antibodies in Rats
Toxins, 2019 Botulinum neurotoxins (BoNT) are potential biothreat agents due to their high lethality, potency, and ease of distribution, thus the development of antitoxins is a high priority to the US government.
Yero Espinoza +9 more
doaj +1 more source