Results 31 to 40 of about 22,801 (243)

Large-Scale Comparison of Toxin and Antitoxins in Listeria monocytogenes

open access: yesToxins, 2020
Toxin−antitoxin systems (TASs) are widely distributed in prokaryotes and encode pairs of genes involved in many bacterial biological processes and mechanisms, including pathogenesis.
José Antonio Agüero   +4 more
doaj   +1 more source

TOXINS AND ANTITOXINS OF BACILLUS DYSENTERIÆ SHIGA

open access: yesJournal of Experimental Medicine, 1919
With the methods which have been described we have separated an exotoxin and an endotoxin from cultures of the Shiga dysenteric bacillus. The study of the nature and effect of the poison of this microorganism is thus simplified.
P. K. Olitsky, I. Kligler
semanticscholar   +1 more source

Clinical Recovery and Circulating Botulinum Toxin Type F in Adult Patient

open access: yesEmerging Infectious Diseases, 2009
A 56-year-old woman in Helena, Montana, USA, who showed clinical signs of paralysis, received antitoxins to botulinum toxins A, B, and E within 24 hours; nevertheless, symptoms progressed to complete quadriplegia. On day 8, she began moving spontaneously,
Jeremy Sobel   +5 more
doaj   +1 more source

SiMa Cells for a Serotype Specific and Sensitive Cell-Based Neutralization Test for Botulinum Toxin A and E

open access: yesToxins, 2017
Botulinum toxins (BoNTs), of which there are seven serotypes, are among the most potent neurotoxins, with serotypes A, B and E causing human botulism.
Nicola Bak   +3 more
doaj   +1 more source

Redefining Therapies for Drug‐Resistant Tuberculosis: Synergistic Effects of Antimicrobial Peptides, Nanotechnology, and Computational Design

open access: yesAdvanced Healthcare Materials, EarlyView.
Antimicrobial peptide (AMP)‐loaded nanocarriers provide a multifunctional strategy to combat drug‐resistant Mycobacterium tuberculosis. By enhancing intracellular delivery, bypassing efflux pumps, and disrupting bacterial membranes, this platform restores phagolysosome fusion and macrophage function.
Christian S. Carnero Canales   +11 more
wiley   +1 more source

SUPER: Upcycling Genetic Parts for Precise Gene Expression Control, Leakage Minimization, and Genetic Circuit Stability

open access: yesAdvanced Science, EarlyView.
To precisely modulate natural and synthetic regulatory parts, SUPER is introduced as a sophisticated and tunable controller of genetic devices without requiring sequence modification on the target. SUPER enhances dynamic range of RNA‐, chemical‐, temperature‐, and protein‐responsive biosensors up to 1011%, and converts biosensors to cover an expanded ...
Taeyang Heo   +3 more
wiley   +1 more source

Diphtheritic myocarditis: A case series and review of literature

open access: yesJournal of Family Medicine and Primary Care, 2020
Myocarditis in patients with diphtheria is a toxin-mediated complication that sets in after one week of onset of respiratory illness. Early administration of antidiphtheritic serum in patients with clinical diphtheria before the onset of myocarditis is ...
Sonali Singh, Nitin Gupta, Pallavi Saple
doaj   +1 more source

Engineered Stable, Antibiotic‐Free, High‐Level Protein Expression in the Probiotic Chassis Escherichia coli Nissle 1917

open access: yesBiotechnology and Bioengineering, EarlyView.
The probiotic E. coli Nissle 1917 was engineered to enable stable and antibiotic free protein expression platforms using native plasmids. Further modification aids in the production of high‐level protein expression for antimicrobial secretion whose activity is comparable to industry standard E. coli BL21.
Halimatun Sakdiah Zainuddin   +2 more
wiley   +1 more source

Oxidative Treatment for Reducing Persistent Populations of Escherichia coli Under Amoxicillin and Gentamicin Pressure

open access: yesJournal of Biophotonics, EarlyView.
Photodynamic inactivation (PDI) with methylene blue and 660 nm LED enhances antibiotic killing of bacteria, accelerating time‐kill kinetics and reducing the MDK99 compared to antibiotics alone. SEM confirms effective cellular damage, demonstrating that PDI potentiates amoxicillin and gentamicin against tolerant bacterial populations. ABSTRACT Bacterial
Bruna C. Correa   +3 more
wiley   +1 more source

Multiple Toxin-Antitoxin Systems in Mycobacterium tuberculosis

open access: yesToxins, 2014
The hallmark of Mycobacterium tuberculosis is its ability to persist for a long-term in host granulomas, in a non-replicating and drug-tolerant state, and later awaken to cause disease.
Ambre Sala   +2 more
doaj   +1 more source

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