Results 91 to 100 of about 2,263 (168)

GC-MS Characterization of Antibacterial, Antioxidant, and Antitrypanosomal Activity of Syzygium aromaticum Essential Oil and Eugenol. [PDF]

Evid Based Complement Alternat Med, 2021
Teles AM, Silva-Silva JV, Fernandes JMP, Abreu-Silva AL, Calabrese KDS, Mendes Filho NE, Mouchrek AN, Almeida-Souza F.   +7 more
europepmc   +1 more source

Metabolite profile of Nectandra oppositifolia Nees & Mart. and assessment of antitrypanosomal activity of bioactive compounds through efficiency analyses. [PDF]

PLoS One, 2021
Alves Conserva GA, Quirós-Guerrero LM, Costa-Silva TA, Marcourt L, Pinto EG, Tempone AG, Fernandes JPS, Wolfender JL, Queiroz EF, Lago JHG.   +9 more
europepmc   +1 more source

Proposed Mechanism for the Antitrypanosomal Activity of Quercetin and Myricetin Isolated from Hypericum afrum Lam.: Phytochemistry, In Vitro Testing and Modeling Studies. [PDF]

Molecules, 2021
Larit F, Elokely KM, Nael MA, Benyahia S, León F, Cutler SJ, Ghoneim MM.   +6 more
europepmc   +1 more source

Phenotypic profiling of Pathogen Box compounds MMV667494 and MMV028694 in bloodstream-form Trypanosoma brucei brucei

Experimental Biology and Medicine
Open-access drug discovery platforms have accelerated hit identification and lead prioritization across multiple diseases and enable systematic repurposing of bioactive compounds beyond their original indications.
Pearl Ihuoma Akazue, Pearl Ihuoma Akazue, Pearl Ihuoma Akazue, Neils Ben Quashie, Neils Ben Quashie, Sue Vaughan, Harry P. de Koning, Theresa Manful Gwira, Theresa Manful Gwira   +8 more
doaj   +1 more source

Aniba rosaeodora (Var. amazonica Ducke) Essential Oil: Chemical Composition, Antibacterial, Antioxidant and Antitrypanosomal Activity. [PDF]

Antibiotics (Basel), 2020
Teles AM, Silva-Silva JV, Fernandes JMP, Calabrese KDS, Abreu-Silva AL, Marinho SC, Mouchrek AN, Filho VEM, Almeida-Souza F.   +8 more
europepmc   +1 more source

Peptidomimetic Vinyl Heterocyclic Inhibitors of Cruzain Effect Antitrypanosomal Activity. [PDF]

J Med Chem, 2020
Chenna BC, Li L, Mellott DM, Zhai X, Siqueira-Neto JL, Calvet Alvarez C, Bernatchez JA, Bernatchez JA, Desormeaux E, Alvarez Hernandez E, Gomez J, McKerrow JH, Cruz-Reyes J, Meek TD.   +13 more
europepmc   +1 more source

Synthesis, study of antileishmanial and antitrypanosomal activity of imidazo pyridine fused triazole analogues. [PDF]

RSC Adv, 2020
Nandikolla A, Srinivasarao S, Karan Kumar B, Murugesan S, Aggarwal H, Major LL, Smith TK, Chandra Sekhar KVG.   +7 more
europepmc   +1 more source

Structure-enabled enhancement of potency in a metronidazole-benznidazole hybrid: design, synthesis, and evaluation of antitrypanosomal activity of a benzylamide-linked 5-nitroimidazole. [PDF]

Front Pharmacol
Velez ASMM, Chaves OA, Costa T, Serpa C, Borges JM, Freire-de-Lima CG, Decote-Ricardo D, Lima MEF.   +7 more
europepmc   +1 more source

Synthesis and Antitrypanosomal Activity of Novel 2‑Nitroimidazole-3,5-Disubstituted Isoxazole Derivatives with Diaryl Ether and Thioether Substituents. [PDF]

ACS Omega
Santos LBB, Carvalho DB, Shiguemoto CYK, Lacerda OD, Silva TS, Portapilla GB, Silva-Filho SE, Guerrero PG, de Albuquerque S, Baroni ACM.   +9 more
europepmc   +1 more source

Pharmacokinetic-pharmacodynamic modeling of benznidazole and its antitrypanosomal activity in a murine model of chronic Chagas disease. [PDF]

PLoS Negl Trop Dis
Assmus F, Adehin A, Hoglund RM, Fortes Francisco A, Lewis MD, Kelly JM, Charman SA, White KL, Shackleford DM, Escudié F, Chatelain E, Scandale I, Tarning J.   +12 more
europepmc   +1 more source