Results 31 to 40 of about 2,263 (168)
Molecules, 2021 Betulinic acid (BA, 3β-hydroxy-lup-20(29)-en-28-oic acid) is a pentacyclic triterpene acid present predominantly in Betula ssp. (Betulaceae) and is also widely spread in many species belonging to different plant families.
André Barreto Cunha +3 more
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In Vitro Antimalarial, Antimicrobial and Trypanocidal Potentials of the Leaf Extract and Fractions of Bridelia ferruginea (Benth.) [PDF]
Trends in Pharmaceutical Sciences, 2023 Bridelia ferruginea Benth. (Euphorbiaceae) is a plant used for various medicinal purposes including the treatment of protozoan infections in many African countries.
Michael Afolayan +2 more
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Antitrypanosomal and antileishmanial activity of prenyl-1,2,3-triazoles [PDF]
MedChemComm, 2017 A series of prenyl 1,2,3-triazoles were prepared from isoprenyl azides and different alkynes. Most of the compounds were active against T. cruzi and L. donovani .
Exequiel O. J. Porta +6 more
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Molecules, 2020 The MeOH/CH2Cl2 (1:1) extracts of the roots and leaves of Beilschmiedia louisii and B. obscura showed potent antitrypanosomal activity during preliminary screening on Trypanosoma brucei brucei.
Christine C. Waleguele +9 more
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Antileishmanial and Antitrypanosomal Activities of the 8-Aminoquinoline Tafenoquine [PDF]
Antimicrobial Agents and Chemotherapy, 2010 ABSTRACT The 8-aminoquinoline tafenoquine showed significant in vitro activity against Leishmania species, including L. donovani amastigotes in macrophages, with 50% inhibitory concentrations (IC 50 s) between 0.1 and 4.0 μM for both ...
Vanessa, Yardley +2 more
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Advances in Pharmacological and Pharmaceutical Sciences, 2022 Malaria and trypanosomiasis are protozoan diseases which pose a devastating challenge to human health and productivity especially, in Africa where their respective vectors (female Anopheles mosquito and tsetse fly) abound.
Aboagye Kwarteng Dofuor +3 more
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Journal of Parasitology Research, 2021 Introduction. Trypanosomiasis is one of the world’s most serious infectious diseases caused by Trypanosoma parasites. Concern about resistance to conventional antitrypanosomal drugs, mosquito vector resistance to existing insecticide side effects of ...
Debela Abdeta +4 more
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Isolation of Antitrypanosomal Compounds from , a Medicinal Plant of Myanmar
Natural Product Communications, 2012 Bioactivity-guided fractionation of an ethanolic extract of Vitis repens led to the isolation of resveratrol ( 1 ), 11- O -acetyl bergenin ( 2 ), and stigmast-4-en-3-one ( 3 ).
Khine Swe Nyunt +5 more
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DNA fingerprinting of five Tabebuia species with reference to their anti-trypanosomal activity [PDF]
Pharmaceutical Sciences Asia, 2022 Tabebuia is the largest genus of the Bignoniaceae family, with great importance due to its beautiful decorative flowering trees, as well as, its remarkable biological activities.
Seham El-Hawary +6 more
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Novel triazine dimers with potent antitrypanosomal activity [PDF]
European Journal of Medicinal Chemistry, 2018 Human African trypanosomiasis (HAT), also known as sleeping sickness is a parasitic disease transmitted by the bite of the 'Glossina' insect, commonly known as the tsetse fly. This disease affects mostly poor populations living in remote rural areas of Africa. Untreated, it is usually fatal. Currently, safe and effective treatments against this disease
Muthusamy Venkatraj +8 more
openaire +2 more sources