Results 51 to 60 of about 17,918 (294)

Current treatment for venom-induced consumption coagulopathy resulting from snakebite. [PDF]

open access: yesPLoS Neglected Tropical Diseases, 2014
Venomous snakebite is considered the single most important cause of human injury from venomous animals worldwide. Coagulopathy is one of the commonest important systemic clinical syndromes and can be complicated by serious and life-threatening ...
Kalana Maduwage, Geoffrey K Isbister
doaj   +1 more source

Appraisal of antivenom production in public laboratories in Latin America during the first semester of 2020: The impact of COVID-19

open access: yesPLoS Neglected Tropical Diseases, 2021
One of the 4 pillars of the World Health Organization (WHO) strategy for the prevention and control of snake bite envenomings is to ensure safe and effective pharmacotherapeutic treatments [1]. The mainstay in the pharmacotherapy of these envenomings, as
J. Gutiérrez   +5 more
semanticscholar   +1 more source

Antivenom supply and demand: An analysis of antivenom availability and utilization in South Africa

open access: yesAfrican Journal of Emergency Medicine, 2023
Snakebites are a neglected tropical disease. In many areas, envenoming incidence and antivenom administration rates are unknown. This study compared antivenom (AV) availability to rates of envenoming and recommendations to treat (RTT) in South Africa.This retrospective study identified, extracted, and reviewed all cases of envenoming (snake bites and ...
Natalie R Neumann   +6 more
openaire   +3 more sources

Focused Proteomics Analysis of Habu Snake (Protobothrops flavoviridis) Venom Using Antivenom-Based Affinity Chromatography Reveals Novel Myonecrosis-Enhancing Activity of Thrombin-Like Serine Proteases

open access: yesFrontiers in Pharmacology, 2021
Snakebites are one of the major causes of death and long-term disability in the developing countries due to the presence of various bioactive peptides and proteins in snake venom.
T. Ogawa   +10 more
semanticscholar   +1 more source

Effectiveness of repeated antivenom therapy for snakebite-related systemic complications

open access: yesJournal of International Medical Research, 2019
Objective This study aimed to determine the effect of repeated antivenom therapy compared with that of single antivenom therapy for treating snakebite-related systemic complications.
Kyung Hoon Park   +7 more
doaj   +1 more source

Recombinant snakebite antivenoms: A cost-competitive solution to a neglected tropical disease? [PDF]

open access: yes, 2017
Snakebite envenoming is a major public health burden in tropical parts of the developing world. In sub-Saharan Africa, neglect has led to a scarcity of antivenoms threatening the lives and limbs of snakebite victims.
Andersen, Mikael R   +3 more
core   +2 more sources

In-Vitro Neutralization of the Neurotoxicity of Coastal Taipan Venom by Australian Polyvalent Antivenom: The Window of Opportunity

open access: yesToxins, 2020
Coastal taipan (Oxyuranus scutellatus) envenoming causes life-threatening neuromuscular paralysis in humans. We studied the time period during which antivenom remains effective in preventing and arresting in vitro neuromuscular block caused by taipan ...
Umesha Madhushani   +4 more
doaj   +1 more source

Challenges and prospects of snake antivenom supply in sub-Saharan Africa

open access: yesPLoS Neglected Tropical Diseases, 2020
1 Health Economics & Outcomes Research (H-CORE) Group, Department of Medicine, Bayero University, Kano, Nigeria, 2 Venom and Antivenom Research Project (VASP), Bayero University, Kano, Nigeria, 3 African Snakebite Research Group (ASRG) Project, Bayero ...
A. Habib   +5 more
semanticscholar   +1 more source

Antivenomics as a tool to improve the neutralizing capacity of the crotalic antivenom: a study with crotamine [PDF]

open access: yesJournal of Venomous Animals and Toxins including Tropical Diseases, 2017
Snakebite treatment requires administration of an appropriate antivenom that should contain antibodies capable of neutralizing the venom. To achieve this goal, antivenom production must start from a suitable immunization protocol and proper venom mixtures.
Teixeira-Araújo, Ricardo   +7 more
openaire   +6 more sources

Determination of potency and paraspecific effects of Androctonus crassicauda (Olivier, 1807) antivenom against Mesobuthus gibbosus (Brullé, 1832) venom (Scorpiones: Buthidae)

open access: yesJournal of Venomous Animals and Toxins including Tropical Diseases, 2007
Scorpion envenomation remains a real health problem in many countries. In scorpionism cases, it is often recommended that patients be treated with species-specific antivenom. Androctonus crassicauda venom has been used as antigen for antivenom production
O. Ozkan   +5 more
doaj   +1 more source

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