Results 51 to 60 of about 12,948 (246)

Does the traditional snakebite severity score correctly classify envenomated patients? [PDF]

open access: yesClinical and Experimental Emergency Medicine, 2016
Objective This study aims to help set domestic guidelines for administration of antivenom to envenomated patients after snakebites. Methods This retrospective observational case series comprised 128 patients with snake envenomation.
Seungho Kang   +2 more
doaj   +1 more source

Immunological cross-reactivity and neutralisation of European viper venoms with the monospecific Vipera berus antivenom ViperaTAb. [PDF]

open access: yes, 2014
Medically important cases of snakebite in Europe are predominately caused by European vipers of the genus Vipera. The mainstay of snakebite therapy is polyclonal antibody therapy, referred to as antivenom.
Al-Abdulla, Ibrahim   +4 more
core   +2 more sources

Immunological profile of antivenoms: Preclinical analysis of the efficacy of a polyspecific antivenom through antivenomics and neutralization assays

open access: yesJournal of Proteomics, 2014
Parenteral administration of animal-derived antivenoms constitutes the mainstay in the treatment of snakebite envenomings. Despite the fact that this therapy has been available for over a century, the detailed understanding of the neutralizing and immunoreactivity profiles of the majority of antivenoms is pending.
Gutiérrez, José María   +4 more
openaire   +5 more sources

A national survey examining recognition, demand for antivenom, and overall level of preparedness for redback spider bites in Japan

open access: yesAcute Medicine & Surgery, 2016
Aim Redback spiders are rapidly becoming a nationwide problem in Japan. The domestic production of antivenom for redback spider bites has been started because of extremely low supply.
Toru Hifumi   +11 more
doaj   +1 more source

Antivenom Evaluation by Electrophysiological Analysis [PDF]

open access: yesToxins, 2017
Scorpion stings on humans are medically relevant because they may contain toxins that specifically target ion channels. During antivenom production, pharmaceutical companies must use a large number of experimental animals to ensure the antivenom’s efficacy according to pharmacopeia methods.
Rita Restano-Cassulini   +3 more
openaire   +4 more sources

An investigation of snakebite antivenom usage in Taiwan

open access: yesJournal of the Formosan Medical Association, 2016
Four types of antivenom are used to treat snakebites by the six species of venomous snakes native to Taiwan. Research into antivenom use in Taiwan and its outcomes, as well as the utility of current Taiwan Poison Control Center guidelines for antivenom ...
Chih-Chuan Lin   +2 more
doaj   +1 more source

Reports of Doses Administered and Adverse Reactions to Snake Antivenom Used in Uruguay in 2018

open access: yesFrontiers in Toxicology, 2021
In Uruguay, around 60 cases of snakebite accidents occur every year that need to be treated with specific antivenom. They are caused by two snakes of Bothrops genus: Bothrops alternatus and Bothrops pubescens.
Alba Negrin   +3 more
doaj   +1 more source

A Novel Apilic Antivenom to Treat Massive, Africanized Honeybee Attacks: A Preclinical Study from the Lethality to Some Biochemical and Pharmacological Activities Neutralization

open access: yesToxins, 2021
Massive, Africanized honeybee attacks have increased in Brazil over the years. Humans and animals present local and systemic effects after envenomation, and there is no specific treatment for this potentially lethal event.
Jhonatha Mota Teixeira-Cruz   +9 more
doaj   +1 more source

The Proteome of African Spitting and Non‐Spitting Cobra Venoms and Cytotoxicity Against Pancreatic Cancer Cells

open access: yesJournal of Applied Toxicology, EarlyView.
ABSTRACT African cobra (Naja spp.) venom contains toxins dominated by proteins and peptides with inter‐ and intra‐specific variations. There are several FDA‐approved drugs from snake venom toxins from other regions, including South America and Asia. Profiling the proteomes of medically important African cobra venoms from different locations will aid in
Benedict C. Offor   +3 more
wiley   +1 more source

Angiotensin-degrading serine peptidase: A new chymotrypsin-like activity in the venom of Bothrops jararaca partially blocked by the commercial antivenom [PDF]

open access: yes, 2012
Snakebite envenomation is considered a highly relevant public health hazard in South America, having an impact in terms of mortality and morbidity.
Carvalho, Daniela Cajado   +6 more
core   +2 more sources

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