Results 61 to 70 of about 17,918 (294)
Population Pharmacokinetics of an Indian F(ab')2 Snake Antivenom in Patients with Russell's Viper (Daboia russelii) Bites. [PDF]
There is limited information on antivenom pharmacokinetics. This study aimed to investigate the pharmacokinetics of an Indian snake antivenom in humans with Russell's viper bites.Patient data and serial blood samples were collected from patients with ...
Geoffrey K Isbister+13 more
doaj +1 more source
Immunological cross-reactivity and neutralisation of European viper venoms with the monospecific Vipera berus antivenom ViperaTAb. [PDF]
Medically important cases of snakebite in Europe are predominately caused by European vipers of the genus Vipera. The mainstay of snakebite therapy is polyclonal antibody therapy, referred to as antivenom.
Al-Abdulla, Ibrahim+4 more
core +2 more sources
The critical time period for administering antivenom: golden hours and missed opportunities
Introduction Antivenom is widely accepted as an effective treatment for snake envenomation. This is despite very limited evidence supporting clinical effectiveness for major envenomation syndromes, and is mainly based on pre-clinical studies and ...
G. Isbister
semanticscholar +1 more source
Background Snakebite in India causes the highest annual rates of death (46,000) and disability (140,000) than any other country. Antivenom is the mainstay treatment of snakebite, whose manufacturing protocols, in essence, have remained unchanged for over
R. R. Senji Laxme+7 more
semanticscholar +1 more source
Naja atra envenomation is one of the most significant clinical snakebite concerns in Taiwan. Taiwanese freeze-dried neurotoxic antivenom (FNAV) is currently used clinically for the treatment of cobra snakebite, and has been shown to limit the mortality ...
Chien-Chun Liu+9 more
semanticscholar +1 more source
A biodistribution study of Hemiscorpius lepturus scorpion venom and available polyclonal antivenom in rats [PDF]
The purpose of the present study was to investigate the biodistribution profile of the venom of Hemiscorpius lepturus, the most dangerous scorpion in Iran.
Babaee, MH+4 more
core +2 more sources
Antivenom Evaluation by Electrophysiological Analysis [PDF]
Scorpion stings on humans are medically relevant because they may contain toxins that specifically target ion channels. During antivenom production, pharmaceutical companies must use a large number of experimental animals to ensure the antivenom’s efficacy according to pharmacopeia methods.
Rita Restano-Cassulini+3 more
openaire +4 more sources
Antivenom availability, delays and use in Australia
Antivenom is the main treatment for snake envenoming and there are ongoing concerns about availability in resource poor regions of the world. However, effective antivenom treatment for snake envenoming requires more than improved availability of safe and
Geoffrey K. Isbister
doaj
An investigation of snakebite antivenom usage in Taiwan
Four types of antivenom are used to treat snakebites by the six species of venomous snakes native to Taiwan. Research into antivenom use in Taiwan and its outcomes, as well as the utility of current Taiwan Poison Control Center guidelines for antivenom ...
Chih-Chuan Lin+2 more
doaj +1 more source
Snakebites are more frequent in the Brazilian Amazon than in other parts of Brazil, representing a high cost for the health system since antivenoms are only available through medical prescription from central municipal hospitals in most cases.
W. Monteiro+11 more
semanticscholar +1 more source