Results 11 to 20 of about 957,186 (389)
Antiviral anticoagulation [PDF]
Research and Practice in Thrombosis and Haemostasis, 2020 Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a novel envelope virus that causes coronavirus disease 2019 (COVID-19). Hallmarks of COVID-19 are a puzzling form of thrombophilia that has elevated D-dimer but only modest effects on other parameters of coagulopathy.
Pryzdial, Edward L. G. +3 more
openaire +3 more sources
Photosensitizing Antivirals [PDF]
Molecules, 2021 Antiviral action of various photosensitizers is already summarized in several comprehensive reviews, and various mechanisms have been proposed for it. However, a critical consideration of the matter of the area is complicated, since the exact mechanisms are very difficult to explore and clarify, and most publications are of an empirical and ...
Kseniya A. Mariewskaya +5 more
openaire +3 more sources
Functional exhaustion of antiviral lymphocytes in COVID-19 patients
Cellular & Molecular Immunology, 2020 In December 2019, a novel coronavirus was first reported in Wuhan, China. It was named by the World Health Organization as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and is responsible for coronavirus disease 2019 (COVID-19).
M. Zheng +7 more
semanticscholar +1 more source
Infection, 1984 After a discussion of the principles of antiviral chemotherapy, treatment and chemoprophylaxis of the following virus infections are reviewed in detail: the various manifestations of herpes simplex virus infections, varicella-zoster, cytomegalovirus infections, Epstein-Barr virus infections, laryngeal papillomas, and influenza A.
openaire +5 more sources
Hepatitis C virus cell-cell transmission and resistance to direct-acting antiviral agents [PDF]
, 2014 Hepatitis C virus (HCV) is transmitted between hepatocytes via classical cell entry but also uses direct cell-cell transfer to infect neighboring hepatocytes.
A Owsianka +72 more
core +16 more sources
SARS-CoV-2 Mpro inhibitors with antiviral activity in a transgenic mouse model
Science, 2021 Targeting the SARS-CoV-2 main protease Vaccines are an important tool in the fight against COVID-19, but developing antiviral drugs is also a high priority, especially with the rise of variants that may partially evade vaccines.
J. Qiao +42 more
semanticscholar +1 more source
Antioxidant Capacity and Antimicrobial Activity of Commercial Samples of Guava Leaves (\u3cem\u3ePsidium guajava\u3c/em\u3e) [PDF]
, 2020 Psidium guajava is a small tree native to South and Central America. Guava leaves have traditionally been used for treating different illnesses. These benefits can be attributed to phenolics and flavonoids produced by guava.
Alsaidi, Sahar +11 more
core +2 more sources
Molnupiravir and Nirmatrelvir-Ritonavir: Oral COVID Antiviral Drugs
Clinical Infectious Diseases, 2022 At a crucial time with rapid spread of Omicron SARS-CoV-2 virus variant globally, the United States Food and Drug Administration has issued an emergency use authorization for two oral antivirals molnupiravir (>18 years) and nirmatrelvir-ritonavir ...
L. Saravolatz +2 more
semanticscholar +1 more source
Nature Biomedical Engineering, 2021 The rapid repurposing of antivirals is particularly pressing during pandemics. However, rapid assays for assessing candidate drugs typically involve in vitro screens and cell lines that do not recapitulate human physiology at the tissue and organ levels.
L. Si +37 more
semanticscholar +1 more source
Effects and mechanism of Aβ1−42 on EV-A71 replication
Virology Journal, 2022 Background β-Amyloid (Aβ) protein is a pivotal pathogenetic factor in Alzheimer’s disease (AD). However, increasing evidence suggests that the brain has to continuously produce excessive Aβ to efficaciously prevent pathogenic micro-organism infections ...
Ming Zhong +8 more
doaj +1 more source