Results 41 to 50 of about 928,338 (389)
Interferon free antiviral treatment of chronic hepatitis C in patients affected by β-thalassemia major [PDF]
, 2017 Chronic hepatitis C (CHC) significantly affects the prognosis of liver disease [1] and health related quality of life (HRQOL) in patients with β-thalassemia major [2, 3].
Biliotti, Elisa +9 more
core +1 more source
Diverse enzymatic activities mediate antiviral immunity in prokaryotes
Science, 2020 Prokaryotic enzymes for viral defense The arms race between prokaryotes and viruses provides a strong evolutionary force to create diverse enzymatic activities that mediate antiviral immune responses. These immune components often cluster together in the
L. Gao +9 more
semanticscholar +1 more source
Efficient and unbiased metagenomic recovery of RNA virus genomes from human plasma samples
Scientific Reports, 2017 RNA viruses cause significant human pathology and are responsible for the majority of emerging zoonoses. Mainstream diagnostic assays are challenged by their intrinsic diversity, leading to false negatives and incomplete characterisation.
Carmen F. Manso +2 more
doaj +1 more source
Cells, 2021 Host cell-intrinsic antiviral responses are largely mediated by pattern-recognition receptor (PRR) signaling and the interferon (IFN) system. The IFN regulatory factor (IRF) family of transcription factors takes up a central role in transcriptional ...
Sandra Wüst +3 more
doaj +1 more source
Liver transplantation for viral hepatitis in 2015 [PDF]
, 2016 Liver transplantation (LT) is a life-saving treatment for patients with end-stage liver disease and for patients with liver cell cancer related to liver disease.
Bortoluzzi, Ilaria +8 more
core +1 more source
mBio, 2018 Emerging coronaviruses (CoVs) cause severe disease in humans, but no approved therapeutics are available. The CoV nsp14 exoribonuclease (ExoN) has complicated development of antiviral nucleosides due to its proofreading activity.
Maria L. Agostini +16 more
semanticscholar +1 more source
Polysaccharides as antiviral agents: antiviral activity of carrageenan [PDF]
Antimicrobial Agents and Chemotherapy, 1987 A number of polysaccharides showed good antiviral activity against several animal viruses. At 5 micrograms/ml, carrageenan prevented the cell monolayer from destruction by herpes simplex virus type 1 (HSV-1) growth. At 10 micrograms/ml, carrageenan reduced the formation of new infectious HSV-1 by almost five logs.
González, M. E. +2 more
openaire +3 more sources
Cooperative effects of RIG-I-like receptor signaling and IRF1 on DNA damage-induced cell death
Cell Death and Disease, 2022 Properly responding to DNA damage is vital for eukaryotic cells, including the induction of DNA repair, growth arrest and, as a last resort to prevent neoplastic transformation, cell death.
David Y. Zander +4 more
doaj +1 more source
Understanding the Wolbachia-mediated inhibition of arboviruses in mosquitoes: progress and challenges [PDF]
, 2014 Arthropod-borne viruses (arboviruses) pose a considerable threat to human and animal health, yet effective control measures have proven difficult to implement, and novel means of controlling their replication in arthropod vectors, such as mosquitoes, are
Dietrich, Isabelle +3 more
core +1 more source
Nanomaterials, 2020 Rapid development of nanotechnology has been in high demand, especially for silver nanoparticles (AgNPs) since they have been proven to be useful in various fields such as medicine, textiles, and household appliances.
Atiqah Salleh +6 more
semanticscholar +1 more source