Results 181 to 190 of about 250,897 (215)
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Antiviral and Non-antiviral Activity of Highly Purified Interferon
Nature New Biology, 1973EVIDENCE has accumulated that interferons exert effects on cells other than causing them to become resistant to viruses. In addition to inducing antiviral and antimicrobial1, activities, interferon preparations of various degrees of purity have been shown to inhibit cell growth2–11, facilitate interferon induction by ‘priming’12–15, suppress interferon
W E, Stewart +5 more
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ANTIVIRAL ACTIVITY OF MEROCYANINE 540
Photochemistry and Photobiology, 1987Abstract Simultaneous exposure to the lipophilic dye merocyanine 540 (MC 540) and white light inactivates several enveloped viruses. The same treatment appears to have little or no effect on pluripotent hematopoietic stem cells, mature red cells, and mature leukocytes. At least some components of the clotting system are spared, too. The molecular basis
F, Sieber +6 more
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The antiviral activity of dideoxycytidine
Journal of Antimicrobial Chemotherapy, 19892',3'-Dideoxycytidine (ddc) is a 2',3'-dideoxypyrimidine nucleotide which has been shown to be active against human immunodeficiency virus type 1 (HIV-1) in cell cultures. This article reviews some of the laboratory studies with this antiviral compound, and available pharmacokinetic and toxicity data from phase 1 studies of ddc alone and in alternation
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Nucleoside analogs with antiviral activity
Biochemical Pharmacology, 1976Effects of chemical agents on viruses are discussed with regard to inhibition of virus adsorption, inhibition of virus penetration and uncoating, and inhibition of an intracellular event. The following nucleosides are discussed with regard to desirable features, toxicity, solubility, and mutagenic and carcinogenic properties: 5-iodo-2'-deoxycytidine, 5-
W H, Prusoff, D C, Ward
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The Antiviral Activities of Tetherin
2013Tetherin (BST2/CD317) has emerged as a key host cell defense molecule, inhibiting the release and spread of diverse enveloped virions from infected cells. In this chapter, I review the molecular and cellular basis for tetherin's antiviral activities and the function of virally encoded countermeasures that disrupt its function. I further describe recent
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Naphthyridines with Antiviral Activity - A Review
Medicinal Chemistry, 2017Naphthyridine scaffold is an important pharmacophore in compounds which have shown various biological activities like antiviral, antimicrobial, anticancer, antiinflammatory and analgesic. This scaffold is also reported to exhibit activity against HIV, HCMV, HSV, HPV and HCV.
Inder P, Singh +2 more
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The Antiviral Activity of Chitosan (Review)
Applied Biochemistry and Microbiology, 2002Data on the inhibitory effect of chitosan on viral infections in animals, plants, and microorganisms are reviewed. The effects of the physicochemical parameters and structure of chitosan on its antiviral activity are analyzed. Possible mechanisms of the inhibitory effect of chitosan on viral infections are discussed.
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A Review of the Antiviral Activity of Berberine
Current Drug Discovery TechnologiesBerberine is an isoquinoline alkaloid with strong pharmacological activity such as analgesic, antioxidant, neuroprotective, antivirus, anti-inflammatory, anti-seizure, anti-obesity, and hypolipidemic effects. Accumulated evidence indicates berberine plays an inhibitory role against infection of numerous viruses, including human immunodeficiency virus,
Fatemeh, Forouzanfar, Zahra, Meshkat
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Antiviral Activity of Glyoxals
Nature, 1957C A, DE BOCK, J, BRUG, J N, WALOP
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