Results 1 to 10 of about 286,395 (314)
Broad-spectrum antiviral agents [PDF]
Frontiers in Microbiology, 2015 Development of highly effective, broad-spectrum antiviral agents is the major objective shared by the fields of virology and pharmaceutics. Antiviral drug development has focused on targeting viral entry and replication, as well as modulating cellular ...
Jun-Da eZhu +3 more
doaj +3 more sources
Antiviral Agents: Discovery to Resistance [PDF]
Viruses, 2020 In the midst of the SARS-CoV-2/Covid-19 outbreak the need for research into, and development of, antiviral agents is brought into sharp focus worldwide for scientists, governments and the public alike [...]
Catherine S. Adamson
doaj +5 more sources
Chapter 12. Antiviral Agents [PDF]
, 1984 This chapter discusses the agents with activity primarily against RNA viruses. The communicable diseases of the respiratory tract are probably the most common cause of symptomatic human infections. The viruses that are causative agents for human respiratory disease comprise the five taxonomically distinct families: orthomyxoviridae, paramyxoviridae ...
James L. Kelley
openalex +4 more sources
Dermatologic Clinics, 2001 The potential severity of many viral infections and the lack of appropriate treatment for these diseases have been a source of endless frustration and helplessness for clinicians. The newly developed field of antiviral therapy is expanding at an astounding rate, with new discoveries each day.
Shijun Ren +7 more
openalex +3 more sources
Breaking the chains: Advancements in antiviral strategies to combat Nipah virus infections [PDF]
International Journal of One Health, 2023 Nipah virus (NiV) is a highly pathogenic zoonotic virus that has caused several outbreaks with high fatality rates in humans and animals, thus, requiring a “One Health” approach. No specific treatment or vaccine is available for NiV infection, making the
Fredmoore L. Orosco
doaj +1 more source
Journal of Global Antimicrobial Resistance, 2022 : Objectives: As a host restriction factor, apolipoprotein B messenger RNA-editing enzyme catalytic polypeptide-like 3G (APOBEC3G or A3G) has been shown to suppress the replication of several viruses including hepatitis B virus (HBV).
Jin Hu +6 more
doaj +1 more source
Establishment and application of a high-throughput screening model for cell adhesion inhibitors
Frontiers in Pharmacology, 2023 The cell adhesion between leukocytes and endothelial cells plays an important balanced role in the pathophysiological function, while excessive adhesion caused by etiological agents is associated with the occurrence and development of many acute and ...
Han Sun +18 more
doaj +1 more source
Curcumin as an Antiviral Agent [PDF]
Viruses, 2020 Curcumin, the primary curcuminoid compound found in turmeric spice, has shown broad activity as an antimicrobial agent, limiting the replication of many different fungi, bacteria and viruses. In this review, we summarize recent studies supporting the development of curcumin and its derivatives as broad-spectrum antiviral agents.
Morgan R. Jennings, Robin J. Parks
openaire +4 more sources
Frontiers in Pharmacology, 2021 Nonalcoholic fatty liver disease (NAFLD), especially its advanced stage nonalcoholic steatohepatitis (NASH), has become a threatened public health problem worldwide. However, no specific drug has been approved for clinical use to treat patients with NASH,
Xue-Kai Wang +3 more
doaj +1 more source
Recent Research Progress: Discovery of Anti-Plant Virus Agents Based on Natural Scaffold
Frontiers in Chemistry, 2022 Plant virus diseases, also known as “plant cancers”, cause serious harm to the agriculture of the world and huge economic losses every year. Antiviral agents are one of the most effective ways to control plant virus diseases.
Jixiang Chen +6 more
doaj +1 more source