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AntiviralDB: an expert-curated database of antiviral agents against human infectious diseases [PDF]

open access: yesmBio
Viral infectious diseases have caused millions of deaths worldwide. Antiviral agents are critical for controlling these infections; however, an open-access database dedicated specifically to antiviral agents remains unavailable.
Jie Huang   +10 more
doaj   +2 more sources

Inhaled Dry Powder of Antiviral Agents: A Promising Approach to Treating Respiratory Viral Pathogens [PDF]

open access: yesViruses
Inhaled dry powder formulations of antiviral agents represent a novel and potentially transformative approach to managing respiratory viral infections. Traditional antiviral therapies in the form of tablets or capsules often face limitations in terms of ...
Tushar Saha   +5 more
doaj   +2 more sources

Breaking the chains: Advancements in antiviral strategies to combat Nipah virus infections [PDF]

open access: yesInternational Journal of One Health, 2023
Nipah virus (NiV) is a highly pathogenic zoonotic virus that has caused several outbreaks with high fatality rates in humans and animals, thus, requiring a “One Health” approach. No specific treatment or vaccine is available for NiV infection, making the
Fredmoore L. Orosco
doaj   +1 more source

Compound IMB-Z inhibits hepatitis B virus replication through increasing APOBEC3G expression and incorporation into viral nucleocapsids

open access: yesJournal of Global Antimicrobial Resistance, 2022
: Objectives: As a host restriction factor, apolipoprotein B messenger RNA-editing enzyme catalytic polypeptide-like 3G (APOBEC3G or A3G) has been shown to suppress the replication of several viruses including hepatitis B virus (HBV).
Jin Hu   +6 more
doaj   +1 more source

Establishment and application of a high-throughput screening model for cell adhesion inhibitors

open access: yesFrontiers in Pharmacology, 2023
The cell adhesion between leukocytes and endothelial cells plays an important balanced role in the pathophysiological function, while excessive adhesion caused by etiological agents is associated with the occurrence and development of many acute and ...
Han Sun   +18 more
doaj   +1 more source

Targeting Liver Sinusoidal Endothelial Cells: An Attractive Therapeutic Strategy to Control Inflammation in Nonalcoholic Fatty Liver Disease

open access: yesFrontiers in Pharmacology, 2021
Nonalcoholic fatty liver disease (NAFLD), especially its advanced stage nonalcoholic steatohepatitis (NASH), has become a threatened public health problem worldwide. However, no specific drug has been approved for clinical use to treat patients with NASH,
Xue-Kai Wang   +3 more
doaj   +1 more source

Recent Research Progress: Discovery of Anti-Plant Virus Agents Based on Natural Scaffold

open access: yesFrontiers in Chemistry, 2022
Plant virus diseases, also known as “plant cancers”, cause serious harm to the agriculture of the world and huge economic losses every year. Antiviral agents are one of the most effective ways to control plant virus diseases.
Jixiang Chen   +6 more
doaj   +1 more source

Efficacy decrease of antiviral agents when administered to ongoing hepatitis C virus infections in cell culture

open access: yesFrontiers in Microbiology, 2022
We report a quantification of the decrease of effectiveness of antiviral agents directed to hepatitis C virus, when the agents are added during an ongoing infection in cell culture vs. when they are added at the beginning of the infection.
Carlos García-Crespo   +21 more
doaj   +1 more source

Silver Nanoparticles as Potential Antiviral Agents

open access: yesPharmaceutics, 2021
Since the early 1990s, nanotechnology has led to new horizons in nanomedicine, which encompasses all spheres of science including chemistry, material science, biology, and biotechnology.
Zubair Ahmed Ratan   +9 more
doaj   +1 more source

Incidence of acute kidney injury (AKI) and outcomes in COVID-19 patients with and without antiviral medications: A retrospective study.

open access: yesPLoS ONE, 2023
BackgroundAcute kidney injury is a complication of COVID-19 and is associated with severity. Despite no specific antiviral treatment strategy, lopinavir/ritonavir and remdesivir have been used.
Seyed Majid Mousavi Movahed   +8 more
doaj   +1 more source

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