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Seven classes of antiviral agents. [PDF]
Cell Mol Life Sci, 2022 AbstractThe viral epidemics and pandemics have stimulated the development of known and the discovery of novel antiviral agents. About a hundred mono- and combination antiviral drugs have been already approved, whereas thousands are in development. Here, we briefly reviewed 7 classes of antiviral agents: neutralizing antibodies, neutralizing recombinant
Ianevski A +7 more
europepmc +8 more sources
Molecular Mechanisms of Antiviral Agents against Dengue Virus [PDF]
Viruses, 2023 Dengue is a major global health threat causing 390 million dengue infections and 25,000 deaths annually. The lack of efficacy of the licensed Dengvaxia vaccine and the absence of a clinically approved antiviral against dengue virus (DENV) drive the ...
Michelle Felicia Lee +2 more
doaj +3 more sources
Antiviral Agents: Discovery to Resistance [PDF]
Viruses, 2020 In the midst of the SARS-CoV-2/Covid-19 outbreak the need for research into, and development of, antiviral agents is brought into sharp focus worldwide for scientists, governments and the public alike [...]
Catherine S. Adamson
doaj +8 more sources
Silver Nanoparticles as Potential Antiviral Agents
Pharmaceutics, 2021 Since the early 1990s, nanotechnology has led to new horizons in nanomedicine, which encompasses all spheres of science including chemistry, material science, biology, and biotechnology.
Zubair Ahmed Ratan +9 more
doaj +2 more sources
Antivirals reduce the formation of key Alzheimer's disease molecules in cell cultures acutely infected with herpes simplex virus type 1. [PDF]
PLoS ONE, 2011 Alzheimer's disease (AD) afflicts around 20 million people worldwide and so there is an urgent need for effective treatment. Our research showing that herpes simplex virus type 1 (HSV1) is a risk factor for AD for the brains of people who possess a ...
Matthew A Wozniak +3 more
doaj +15 more sources
Broad-spectrum antiviral agents [PDF]
Frontiers in Microbiology, 2015 Development of highly effective, broad-spectrum antiviral agents is the major objective shared by the fields of virology and pharmaceutics. Antiviral drug development has focused on targeting viral entry and replication, as well as modulating cellular ...
Jun-Da eZhu +3 more
doaj +3 more sources
Journal of Thrombosis and Haemostasis, 2020 Antiviral drugs are administered in patients with severe COVID‐19 respiratory syndrome, including those treated with direct oral anticoagulants (DOACs).
Sophie Testa, Gian Battista Danzi
exaly +2 more sources
Tannins as Antiviral Agents [PDF]
, 2020 Tannins possess a variety of biological effects, not a small part of which is of medical significance. Tannins, isolated from plants as well as synthetically obtained, manifest activity against a large spectrum of viruses: enteroviruses (polio- and ...
Angel S. Galabov +2 more
openaire +5 more sources
Medicinal chemistry strategies toward host targeting antiviral agents
Medicinal Research Reviews, 2020 Direct‐acting antiviral agents (DAAs) represent a class of drugs targeting viral proteins and have been demonstrated to be very successful in combating viral infections in clinic.
Xingyue Ji, Zhuo-rong Li, Xingyue Ji
exaly +2 more sources
Engineering recombinantly expressed lectin-based antiviral agents [PDF]
Frontiers in Cellular and Infection Microbiology, 2022 Cyanovirin-N (CV-N), a lectin from Nostoc ellipsosporum was found an infusion inhibitory protein for human immunodeficiency virus (HIV)-1. A tandem-repeat of the engineered domain-swapped dimer bound specific sites at hemagglutinin (HA), Ebola and HIV ...
Irene Maier
doaj +2 more sources