Results 31 to 40 of about 3,598,763 (344)
Kinase Inhibitors as Underexplored Antiviral Agents
Journal of Medicinal Chemistry, 2021 Viral infections are a major health problem; therefore, there is an urgent need for novel therapeutic strategies. Antivirals used to target proteins encoded by the viral genome usually enhance drug resistance generated by the virus.
Javier García-Cárceles +3 more
semanticscholar +1 more source
International Journal of Molecular Sciences, 2020 Essential oils have shown promise as antiviral agents against several pathogenic viruses. In this work we hypothesized that essential oil components may interact with key protein targets of the 2019 severe acute respiratory syndrome coronavirus 2 (SARS ...
J. D. da Silva +3 more
semanticscholar +1 more source
Plant-derived lignans as potential antiviral agents: a systematic review
Phytochemistry Reviews, 2021 Medicinal plants are one of the most important sources of antiviral agents and lead compounds. Lignans are a large class of natural compounds comprising two phenyl propane units. Many of them have demonstrated biological activities, and some of them have
Xin-Ya Xu +4 more
semanticscholar +1 more source
Lycorine Derivative LY-55 Inhibits EV71 and CVA16 Replication Through Downregulating Autophagy
Frontiers in Cellular and Infection Microbiology, 2019 Hand, foot, and mouth disease (HFMD) is a global health concern, especially in the Asia-Pacific region. HFMD caused by Enterovirus 71 (EV71) and Coxsackievirus A16 (CVA16) infection is usually self-limited but occasionally leads to severe pulmonary edema,
Huiqiang Wang +7 more
doaj +1 more source
ACS Nano, 2021 Therapeutic options for the highly pathogenic human severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causing the current pandemic coronavirus disease (COVID-19) are urgently needed.
Ã. Serrano-Aroca +22 more
semanticscholar +1 more source
mBio, 2022 Amino acid substitutions I38T and E23K in the influenza polymerase acidic (PA) protein lead to reduced susceptibility to the influenza antiviral drug baloxavir.
Paulina Koszalka +4 more
doaj +1 more source
mSphere, 2016 Antimicrobial-resistant infections are an urgent public health threat, and development of novel antimicrobial therapies has been painstakingly slow. Polymicrobial infections are increasingly recognized as a significant source of severe disease and also ...
Jeffrey A. Melvin +6 more
doaj +1 more source
Can biopolymers act as antiviral agents?
eXPRESS Polymer Letters, 2020 editorial
J. Seppala, S. Borandeh
doaj +1 more source
Complexes of Ruthenium(II) as Promising Dual-Active Agents against Cancer and Viral Infections
Pharmaceuticals, 2023 Poor responses to medical care and the failure of pharmacological treatment for many high-frequency diseases, such as cancer and viral infections, have been widely documented.
Assunta D’Amato +6 more
doaj +1 more source
, 2009 Antiviral agents are drugs approved in the USA by the Food and Drug Administration (FDA) for the treatment or control of viral infections. Available antiviral agents mainly target stages in the viral life cycle. The target stages in the viral life cycle are; viral attachment to host cell, uncoating, synthesis of viral mRNA, translation of mRNA ...
Paintsil, E., Cheng, Yung-Chi
openaire +2 more sources