Results 31 to 40 of about 3,623,509 (414)

Targeting Liver Sinusoidal Endothelial Cells: An Attractive Therapeutic Strategy to Control Inflammation in Nonalcoholic Fatty Liver Disease

open access: yesFrontiers in Pharmacology, 2021
Nonalcoholic fatty liver disease (NAFLD), especially its advanced stage nonalcoholic steatohepatitis (NASH), has become a threatened public health problem worldwide. However, no specific drug has been approved for clinical use to treat patients with NASH,
Xue-Kai Wang   +3 more
doaj   +1 more source

Repositioning potentials of smallpox vaccines and antiviral agents in monkeypox outbreak: A rapid review on comparative benefits and risks

open access: yesHealth Science Reports, 2022
There is a sought for vaccines and antiviral agents as countermeasures for the recent monkeypox outbreak. Here, we aimed to review and discuss the repurposing potentials of smallpox vaccines and drugs in monkeypox outbreaks based on their comparative ...
Md. Rabiul Islam   +6 more
semanticscholar   +1 more source

Curcumin as an Antiviral Agent [PDF]

open access: yesViruses, 2020
Curcumin, the primary curcuminoid compound found in turmeric spice, has shown broad activity as an antimicrobial agent, limiting the replication of many different fungi, bacteria and viruses. In this review, we summarize recent studies supporting the development of curcumin and its derivatives as broad-spectrum antiviral agents.
Morgan R. Jennings, Robin J. Parks
openaire   +4 more sources

Synthesis and Applications of Nitrogen-Containing Heterocycles as Antiviral Agents

open access: yesMolecules, 2022
Viruses have been a long-term source of infectious diseases that can lead to large-scale infections and massive deaths. Especially with the recent highly contagious coronavirus (COVID-19), antiviral drugs were developed nonstop to deal with the emergence
Tuyen N. Tran, M. Henary
semanticscholar   +1 more source

Isatin derivatives as broad-spectrum antiviral agents: the current landscape

open access: yesMedicinal Chemistry Research, 2022
In recent decades, several viruses have resulted in large outbreaks with serious health, economic and social consequences. The current unprecedented outbreak of the new coronavirus, SARS-COV-2, necessitates intensive efforts for delivering effective ...
T. Elsaman   +6 more
semanticscholar   +1 more source

Recent Research Progress: Discovery of Anti-Plant Virus Agents Based on Natural Scaffold

open access: yesFrontiers in Chemistry, 2022
Plant virus diseases, also known as “plant cancers”, cause serious harm to the agriculture of the world and huge economic losses every year. Antiviral agents are one of the most effective ways to control plant virus diseases.
Jixiang Chen   +6 more
doaj   +1 more source

Efficacy decrease of antiviral agents when administered to ongoing hepatitis C virus infections in cell culture

open access: yesFrontiers in Microbiology, 2022
We report a quantification of the decrease of effectiveness of antiviral agents directed to hepatitis C virus, when the agents are added during an ongoing infection in cell culture vs. when they are added at the beginning of the infection.
Carlos García-Crespo   +21 more
doaj   +1 more source

Phytochemicals from Plant Foods as Potential Source of Antiviral Agents: An Overview

open access: yesPharmaceuticals, 2021
To date, the leading causes of mortality and morbidity worldwide include viral infections, such as Ebola, influenza virus, acquired immunodeficiency syndrome (AIDS), severe acute respiratory syndrome (SARS) and recently COVID-19 disease, caused by the ...
T. Behl   +15 more
semanticscholar   +1 more source

Incidence of acute kidney injury (AKI) and outcomes in COVID-19 patients with and without antiviral medications: A retrospective study.

open access: yesPLoS ONE, 2023
BackgroundAcute kidney injury is a complication of COVID-19 and is associated with severity. Despite no specific antiviral treatment strategy, lopinavir/ritonavir and remdesivir have been used.
Seyed Majid Mousavi Movahed   +8 more
doaj   +1 more source

Ribonucleases as antiviral agents [PDF]

open access: yesMolecular Biology, 2014
Many ribonucleases (RNases) are able to inhibit the reproduction of viruses in infected cell cultures and laboratory animals, but the molecular mechanisms of their antiviral activity remain unclear. The review discusses the well-known RNases that possess established antiviral effects, including both intracellular RNases (RNase L, MCPIP1 protein, and ...
Ilinskaya O., Mahmud R.
openaire   +5 more sources

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