Results 1 to 10 of about 70,722 (95)
Antiviral defense systems in the rumen microbiome [PDF]
mSystemsThe continuous interaction between phages and their respective hosts has resulted in the evolution of multiple bacterial immune mechanisms. However, the diversity and prevalence of antiviral defense systems in complex communities are still unknown.
Johan S. Sáenz +2 more
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Adaptive modification of antiviral defense systems in microbial community under Cr-induced stress [PDF]
MicrobiomeBackground The prokaryotic antiviral defense systems are crucial for mediating prokaryote-virus interactions that influence microbiome functioning and evolutionary dynamics. Despite the prevalence and significance of prokaryotic antiviral defense systems,
Dan Huang +7 more
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Aging impairs the antiviral defense in Caenorhabditis elegans due to loss of DRH-1/RIG-I deSUMOylation by ULP-4/SENP7 [PDF]
EMBO ReportsInnate immune defense relies on post-translational modifications (PTMs) to protect against viral infections. SUMOylation plays complex roles in viral replication and antiviral defenses in mammals and has been implicated in age-associated diseases ...
Yun Zhang, Andrew V Samuelson
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Argonaute 5-mediated antiviral defense and viral counter-defense in Nicotiana benthamiana [PDF]
Virus Research, 2023 The argonaute (AGO) family proteins play a crucial role in preventing viral invasions through the plant antiviral RNA silencing pathway, with distinct AGO proteins recruited for specific antiviral mechanisms.
Chin-Wei Tu +6 more
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SUMOylation in Viral Replication and Antiviral Defense [PDF]
Advanced Science, 2022 SUMOylation is a ubiquitination‐like post‐translational modification that plays an essential role in the regulation of protein function. Recent studies have shown that proteins from both RNA and DNA virus families can be modified by SUMO conjugation ...
Yao Fan +10 more
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Emerging Microbes and Infections, 2021 African swine fever virus (ASFV) is the causal agent of a fatal disease of domestic swine for which no effective antiviral drugs are available. Recently, it has been shown that microtubule-targeting agents hamper the infection cycle of different viruses.
Samvel Sirakanyan +19 more
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Journal of Animal Science and Biotechnology, 2020 Background The ongoing African swine fever virus (ASFv) epidemic has had a major impact on pig production globally and biosecurity efforts to curb ASFv infectivity and transmission are a high priority.
Joshua A. Jackman +3 more
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A Requirement for Argonaute 4 in Mammalian Antiviral Defense
Cell Reports, 2020 Summary: While interferon (IFN) responses are critical for mammalian antiviral defense, induction of antiviral RNA interference (RNAi) is evident. To date, individual functions of the mammalian RNAi and micro RNA (miRNA) effector proteins Argonautes 1–4 (
Fatemeh Adiliaghdam +7 more
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Dendritic Cells and Antiviral Defense
Viruses, 2020 Dendritic cells (DCs) play a fundamental and central role in the immune response, acting as a critical link between the innate and adaptive branches of immunity [...]
Robbie B. Mailliard
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