Honey Bee Viruses, Colony Health, and Antiviral Defense
Proceedings, 2020 Honey bee colony losses are influenced by multiple abiotic and biotic factors, including viruses. To investigate the effects of RNA viruses on honey bees, we infected bees with a model virus (Sindbis-GFP) in the presence or absence of double-stranded RNA
Katie F. Daughenbaugh +4 more
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UNC93B1 mediates innate inflammation and antiviral defense in the liver during acute murine cytomegalovirus infection. [PDF]
PLoS ONE, 2012 Antiviral defense in the liver during acute infection with the hepatotropic virus murine cytomegalovirus (MCMV) involves complex cytokine and cellular interactions.
Meredith J Crane +2 more
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RNA interference: a multifaceted innate antiviral defense [PDF]
Retrovirology, 2008 The RNA interference mechanism utilizes short RNA duplexes to either suppress or induce target gene expression. Post-transcriptional regulation mediated by microRNA is an integral component of innate antiviral defense. The magnitude and the efficiency of
Kumar Ajit
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Targeting β2-Adrenergic Receptor Stability With Lycorine Reveals a Host-Directed Pathway for Antiviral Defense Against Poxviruses. [PDF]
Adv Sci (Weinh)Chronic stress drives autophagy‐mediated β2‐AR degradation, impairing antiviral immunity and promoting poxvirus lethality. Lycorine directly stabilizes β2‐AR to restore host defense, suppress excessive inflammation and improve survival. ABSTRACT Psychological stress is a pervasive yet poorly understood modulator of infectious disease outcomes. Here, we
Zhang X +12 more
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Antiviral potential of cathelicidins [PDF]
, 2014 The global burden of morbidity and mortality arising from viral infections is high; however, the development of effective therapeutics has been slow.
Davidson, Donald J +8 more
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Next generation sequencing for studying viruses and RNA silencing-based antiviral defense in crop plants [PDF]
, 2014 The main objectives of this work have been to use next generation sequencing (NGS) and develop bioinformatics tools for plant virus diagnostics and genome reconstruction as well as for investigation of RNA silencing-based antiviral defense.
Seguin, Jonathan
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Model showing how OsNF-YAs manipulate the JA-mediated antiviral defense.
, 2022 In healthy plants, some OsNF-YAs combine with OsMYC2/3 transcription factors and slightly affect the JA-mediated antiviral defense. In virus-infected plants, OsNF-YAs are markedly induced by RSV or SRBSDV and dissociate the OsMYC2/3-OsMED25 complex ...
Jianping Chen (54279) +6 more
core +1 more source
Mst1 shuts off cytosolic antiviral defense through IRF3 phosphorylation [PDF]
, 2016 Cytosolic RNA/DNA sensing elicits primary defense against viral pathogens. Interferon regulatory factor 3 (IRF3), a key signal mediator/transcriptional factor of the antiviral-sensing pathway, is indispensible for interferon production and antiviral ...
Zhou, Yao +15 more
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Cell Reports, 2018 Summary: Rhinovirus is a leading cause of acute respiratory infections and asthma attacks, but infections are also frequently cleared from the nasal mucosa without causing symptoms.
Valia T. Mihaylova +7 more
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Virophages and retrotransposons colonize the genomes of a heterotrophic flagellate
eLife, 2021 Virophages can parasitize giant DNA viruses and may provide adaptive anti-giant virus defense in unicellular eukaryotes. Under laboratory conditions, the virophage mavirus integrates into the nuclear genome of the marine flagellate Cafeteria burkhardae ...
Thomas Hackl +4 more
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