Results 21 to 30 of about 951,212 (251)

What Are the Functional Roles of Piwi Proteins and piRNAs in Insects?

Insects, 2023
Research on Piwi proteins and piRNAs in insects has focused on three experimental models: oogenesis and spermatogenesis in Drosophila melanogaster, the antiviral response in Aedes mosquitoes and the molecular analysis of primary and secondary piRNA ...
Dulce Santos, Min Feng, Anna Kolliopoulou, Clauvis N. T. Taning, Jingchen Sun, Luc Swevers   +5 more
doaj   +1 more source

Optineurin negatively regulates the induction of IFNβ in response to RNA virus infection [PDF]

, 2010
The innate immune response provides a critical defense against microbial infections, including viruses. These are recognised by pattern recognition receptors including Toll-like receptors (TLRs) and RIG-I like helicases (RLHs).
Harris, M., Macdonald, A., Kohl, A., Richards, KH, Wetherill, L, Kohl, Alain, MacDonald, A, Mankouri, Jamel, Kohl, A, Elliott, Richard M., Elliott, RM, Alain Kohl, Wetherill, L.F., Rennos Fragkoudis, Harris Mark, Andrew Macdonald, Richards Kathryn H., Richards, K.H., Richards, K, Laura F Wetherill, Mankouri, J., Richards, Kathryn H., Mankouri, J, Jamel Mankouri, Elliott, R.M., Wetherill Laura F., Fragkoudis, R., Richard M Elliott, Macdonald, Andrew, Harris, M, Wetherill, Laura F., Kohl Alain, Elliott Richard M., Macdonald Andrew, Wetherill, LF, Elliott, Richard Michael, Mark Harris, Harris, Mark, Fragkoudis, R, Kathryn H Richards, Fragkoudis, Rennos, Mankouri Jamel, Fragkoudis Rennos   +42 more
core   +1 more source

Defense Mechanisms against Viral Infection in Drosophila: RNAi and Non-RNAi

Viruses, 2018
RNAi is considered a major antiviral defense mechanism in insects, but its relative importance as compared to other antiviral pathways has not been evaluated comprehensively.
Luc Swevers, Jisheng Liu, Guy Smagghe
doaj   +1 more source

Comparative analysis of the lambda-interferons IL-28A and IL-29 regarding their transcriptome and their antiviral properties against hepatitis C virus. [PDF]

, 2010
Specific differences in signaling and antiviral properties between the different Lambda-interferons, a novel group of interferons composed of IL-28A, IL-28B and IL-29, are currently unknown.
Ralf Bartenschlager, Brand, Stephan, Burkhard Göke, Göke, Burkhard, Artur Kaul, Stephan Brand, Beigel, Florian, Kaul, Artur, Kathrin Zitzmann, Helmut M. Diepolder, Diegelmann, Julia, Diepolder, Helmut M., Christoph J Auernhammer, Bartenschlager, Ralf, Helmut M Diepolder, Christoph J. Auernhammer, Julia Diegelmann, Florian Beigel, Zitzmann, Kathrin, Auernhammer, Christoph J., Bartenschlager Ralf, Auernhammer Christoph J., Diegelmann Julia, Zitzmann Kathrin, Diepolder Helmut M., Göke Burkhard, Brand Stephan, Kaul Artur, Beigel Florian   +28 more
core   +1 more source

Vaccinia virus protein A46R targets multiple Toll-like-interleukin-1 receptor adaptors and contributes to virulence [PDF]

, 2005
Viral immune evasion strategies target key aspects of the host antiviral response. Recently, it has been recognized that Toll-like receptors (TLRs) have a role in innate defense against viruses.
Nathan W. Bartlett, Geoffrey L. Smith, Haga, Ismar R, Geraldine Maloney, Bowie, Andrew G., Bartlett, Nathan W., Martina Schröder, Ismar R. Haga, Haga, Ismar R., Patrick C. Reading, Andrew G. Bowie, Fitzgerald, Katherine A, Smith, Geoffrey L, Schroeder, Martina, Reading, Patrick C, Smith, Geoffrey L., Katherine A. Fitzgerald, Bartlett, Nathan W, Julianne Stack, Maloney, Geraldine, Bowie, Andrew G, Schröder, Martina, Reading, Patrick C., Stack, Julianne, Fitzgerald, Katherine A., Reading, Patrick   +25 more
core   +1 more source

Virus and dsRNA-triggered transcriptional responses reveal key components of honey bee antiviral defense

Scientific Reports, 2017
Recent high annual losses of honey bee colonies are associated with many factors, including RNA virus infections. Honey bee antiviral responses include RNA interference and immune pathway activation, but their relative roles in antiviral defense are not ...
Laura M. Brutscher, Katie F. Daughenbaugh, Michelle L. Flenniken   +2 more
doaj   +1 more source

Analysis of the Involvement of an Inducible Arabidopsis RNA-Dependent RNA Polymerase in Antiviral Defense

Molecular Plant-Microbe Interactions, 2003
RNA-dependent RNA polymerases (RdRPs) have been implicated in posttranscriptional gene silencing (PTGS) and antiviral defense. An Arabidopsis RdRP (SDE1/SGS2) has been previously shown to be required for transgene-induced PTGS but has no general role in ...
Diqiu Yu, Baofang Fan, Stuart A. MacFarlane, Zhixiang Chen   +3 more
doaj   +1 more source

Rhabdoviruses, Antiviral Defense, and SUMO Pathway

Viruses, 2018
Small Ubiquitin-like MOdifier (SUMO) conjugation to proteins has essential roles in several processes including localization, stability, and function of several players implicated in intrinsic and innate immunity.
Faten El Asmi, Carlos Eduardo Brantis-de-Carvalho, Danielle Blondel, Mounira K. Chelbi-Alix   +3 more
doaj   +1 more source

Roles and programming of Arabidopsis ARGONAUTE proteins during Turnip mosaic virus infection. [PDF]

PLoS Pathogens, 2015
In eukaryotes, ARGONAUTE proteins (AGOs) associate with microRNAs (miRNAs), short interfering RNAs (siRNAs), and other classes of small RNAs to regulate target RNA or target loci.
Hernan Garcia-Ruiz, Alberto Carbonell, J Steen Hoyer, Noah Fahlgren, Kerrigan B Gilbert, Atsushi Takeda, Annalisa Giampetruzzi, Mayra T Garcia Ruiz, Michaela G McGinn, Nicholas Lowery, Maria T Martinez Baladejo, James C Carrington   +11 more
doaj   +1 more source

Prophage identification and molecular analysis in the genomes of Pseudomonas aeruginosa strains isolated from critical care patients

mSphere, 2023
Prophages are bacteriophages integrated into the bacterial host’s chromosome. This research aims to analyze and characterize the existing prophages within a collection of 53 Pseudomonas aeruginosa strains from intensive care units (ICUs) in Portugal and ...
Manuel González de Aledo, Lucia Blasco, Maria Lopez, Concha Ortiz-Cartagena, Inés Bleriot, Olga Pacios, Marta Hernández-García, Rafael Cantón, Maria Tomas   +8 more
doaj   +1 more source