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Oral Antiviral Defense: Saliva- and Beverage-like Hypotonicity Dynamically Regulate Formation of Membraneless Biomolecular Condensates of Antiviral Human MxA in Oral Epithelial Cells. [PDF]
Sehgal PB +3 more
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Discovery of new antiviral defense mechanisms
Hirsch, Ivan, Grantz Šašková, Klára
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ABSTRACT The synthesis and accumulation of active ingredients in medicinal plants are distributed in specific organs, tissues, and cell types, which are important for the exploitation of medicinal plants. However, the fine distribution of active ingredients is difficult to know. Here, the system of mass spectrometry imaging (MSI) integrated with single‐
HaiSheng Zeng +14 more
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WRKY Transcription Factors: Integral Regulators of Defence Responses to Biotic Stress in Crops
ABSTRACT Crops are continually challenged by biotic stresses, including fungal, bacterial and viral pathogens and insect pests, which cause substantial yield and quality losses worldwide. WRKY transcription factors constitute a plant‐specific and functionally diverse family that is central to immune regulation.
Dongjiao Wang +8 more
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Autophagy and antiviral defense
IUBMB Life, 2021AbstractTargeting intracellular components for lysosomal degradation by autophagy not only maintains cellular homeostasis but also counteracts the effects of external stimuli, including invading pathogens. Among various kinds of pathogens, viruses have been extensively shown to induce autophagy to benefit viral growth in infected cells and to modulate ...
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Neutrophils and antiviral defense
The Pediatric Infectious Disease Journal, 1986Revue des interactions entre neutrophiles et virus. Ces etudes in vitro ont mis en evidence une reaction cytotoxique a mediation neutrophile vis-a-vis des cellules infectees par virus en presence d'anticorps seul, ou de complement seul.
H, Faden, P, Ogra
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Bacterial multicellular behavior in antiviral defense
Current Opinion in Microbiology, 2023Multicellular behaviour benefits seemingly simple organisms such as bacteria, by improving nutrient uptake, resistance to stresses or by providing advantages in predatory interactions. Several recent studies have shown that this also extends to the defense against bacteriophages, which are omnipresent in almost all habitats.
Luthe, Tom +3 more
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Interferon-independent antiviral defense
Science, 2017Immunology Antiviral responses are normally initiated by interferon production, which stimulates the phosphorylation and activation of STAT1 and STAT2. These transcription factors, in complex with the transcriptional regulator IRF9, mediate antiviral gene expression. Wang et al.
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Hippo-sized antiviral defenses
Science Signaling, 2017The Hippo signaling pathway modulates the strength of antiviral responses according to nutritional status or cell density.
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