Results 191 to 200 of about 951,212 (251)

RNA editing system: Balancing altruistic antiviral defense and fitness trade-offs in fungi. [PDF]

mLife
Du Y, Jiang D, Liu H.
europepmc   +1 more source

Microbiome Dynamics During Translocation of the Critically Endangered Frog Craugastor ranoides

Animal Conservation, EarlyView.
A female Craugastor ranoides fitted with an LB‐2X radio transmitter using a silicone waist‐belt harness for post‐translocation monitoring. ABSTRACT Amphibian populations are declining, and species are going extinct due to habitat loss, climate change, and emerging infectious disease, prompting the increasing use of translocations as a conservation tool.
Xavier A. Harrison, Katherine Herborn, Gilbert Alvarado, María Marta Chavarría, Kirsty J. Marsh, Alexander D.M. Wilson, Alexandra C. North, Victoria E. P. Wakeham, Roberto Fernández, Héctor Zumbado‐Ulate, Jon Bielby, Robert Puschendorf   +11 more
wiley   +1 more source

Type 2 Diabetes Reduces IFN-α2 and Compromises Antiviral Defense: Evidence From Mendelian Randomization and H1N1-Infected Diabetic Mice. [PDF]

Diabetes
Lyu S, Wu J, Ma W, Sun L, Xing S, Zhang H, Shao F, Li M, Zhu Y, Xiong X, Han J.   +10 more
europepmc   +1 more source

Serotonin Degradation and Lipid Metabolism Regulate Human Tc2 Cell Effector Functions

Allergy, EarlyView.
Human Tc2 cells exhibit a metabolically active phenotype characterized by enhanced glycolysis, mitochondrial respiration, and fatty acid uptake dependent on PPARγ. Alarmins strongly amplify IL‐5 and IL‐13 production in Tc2 cells, supporting a shared immunometabolic program across type 2 lymphocytes.
Sabrina de Souza Ferreira, Lisa Holla, Sophia Björkander, Marie Kaarup Bek, Lorenz Wirth, Patrick A. Shearer, Jesper Säfholm, Erik Sachs, Mamdoh Al‐Ameri, Kasra Vali, Sandra Ekström, Erik Melén, Jenny Mjösberg, Christopher Andrew Tibbitt   +13 more
wiley   +1 more source

Th2 cytokine-induced mucociliary remodeling in chronic rhinosinusitis: implications for antiviral defense and epithelial function. [PDF]

Respir Res
Theorell J, Drnevich J, Jovanovic Gasovic S, Lawate B, Lee VS, Veiga-Lopez A.   +5 more
europepmc   +1 more source

Basophils in Immunity: Activation Pathways, Roles in Allergy and AllergoOncology and Application of the Basophil Activation Test

Allergy, EarlyView.
ABSTRACT Basophils, the least abundant leukocytes, are increasingly recognised as potent immunomodulators. Upon activation, they rapidly release preformed granule‐associated mediators including histamine and lipid mediators such as LTC4, while cytokine production occurs over a longer timescale, contributing to downstream immune responses.
Jitesh Chauhan, Sofia Vlasova, Alicia Chenoweth, Debra H. Josephs, Heather J. Bax, Sophia N. Karagiannis   +5 more
wiley   +1 more source

Host breed and geography shape the antiviral defense landscape of the bovine rumen microbiome. [PDF]

ISME Commun
Faleiros CA, Gonçalves OS, Nunes AT, Pires CS, Poleti MD, Fukumasu H.   +5 more
europepmc   +1 more source

Understanding the Type 2 Immunity: An Evolving View Beyond Allergic Diseases

Allergy, EarlyView.
ABSTRACT Type 2 (T2) immunity is classically associated with defense against helminths and environmental threats, from a physiological perspective, and with allergies and eosinophilic inflammatory diseases, in a pathological sense. However, growing evidence reveals that T2 pathways also support other essential homeostatic functions, including tissue ...
Rodrigo Jiménez‐Saiz, Salvador Iborra, Carlos Blanco, Ruperto González‐Pérez, Emilio Nuñez‐Borque, Can Zeyneloglu, Huseyn Babayev, Ozlem Göksel, Tuncay Göksel, Musa Khaitov, Dmitry Kudlay, Yadong Gao, Mustafa Sevim, Marie‐Charlotte Brüggen, Oral Alpan, Ming Wang, Luo Zhang, María J. Torres, Mohamed Shamji, Mübeccel Akdis, Kari C. Nadeau, Ismail Ogulur, Cezmi A. Akdis   +22 more
wiley   +1 more source

Post-Translational Modifications of TOE3 Regulate Antiviral Defense in Tobacco. [PDF]

Adv Sci (Weinh)
Jiao B, Wu B, Lin H, Xi D.
europepmc   +1 more source

The Origins of Allergy: An Outside‐In, Bioenergetic Hypothesis

Allergy, EarlyView.
ABSTRACT Allergic disease has risen too rapidly for inherited susceptibility to explain it, and the risk variants so far reported lie in the epithelial barrier and in type‐2 immunity. We propose a five‐layer model in which epithelial barrier and bioenergetic dysfunction may precede and promote type‐2 immune deviation rather than arise solely as its ...
Peter K. Smith, Nicholas P. West, Stanley Du Preez, Hugh A. Sampson, Peter W. Hellings, David Price, Liam O'Mahony, Carina Venter, Cezmi A. Akdis, Gil Yosipovitch   +9 more
wiley   +1 more source