Results 21 to 30 of about 70,871 (236)
Selective Autophagy Receptors in Antiviral Defense
Trends in Microbiology, 2021 Autophagy ensures the degradation of cytosolic substrates by the lysosomal pathway. Cargoes destined to be eliminated are confined within double-membrane vesicles called autophagosomes, prior to fusion with endolysosomal vacuoles. Autophagy receptors selectively interact with cargoes and route them to elongating autophagic membranes, a process referred
Viret, Christophe +4 more
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Virophages and retrotransposons colonize the genomes of a heterotrophic flagellate
eLife, 2021 Virophages can parasitize giant DNA viruses and may provide adaptive anti-giant virus defense in unicellular eukaryotes. Under laboratory conditions, the virophage mavirus integrates into the nuclear genome of the marine flagellate Cafeteria burkhardae ...
Thomas Hackl +4 more
doaj +1 more source
Antiviral RNAi in Insects and Mammals: Parallels and Differences
Viruses, 2019 The RNA interference (RNAi) pathway is a potent antiviral defense mechanism in plants and invertebrates, in response to which viruses evolved suppressors of RNAi.
Susan Schuster +2 more
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What Are the Functional Roles of Piwi Proteins and piRNAs in Insects?
Insects, 2023 Research on Piwi proteins and piRNAs in insects has focused on three experimental models: oogenesis and spermatogenesis in Drosophila melanogaster, the antiviral response in Aedes mosquitoes and the molecular analysis of primary and secondary piRNA ...
Dulce Santos +5 more
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Cell Reports, 2018 Summary: Rhinovirus is a leading cause of acute respiratory infections and asthma attacks, but infections are also frequently cleared from the nasal mucosa without causing symptoms.
Valia T. Mihaylova +7 more
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Countering Counter-Defense to Antiviral RNAi
Trends in Microbiology, 2020 RNA interference (RNAi) is a powerful host defense mechanism against viruses. As a counter-defense, many viruses encode suppressors of RNAi, which - in plants - has provoked counter-counter-defense strategies. Recently, a mechanism was proposed in Drosophila (Zhang et al.) wherein a long noncoding RNA senses a virus-encoded RNAi suppressor to activate ...
Betting, V., Rij, R.P. van
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Honey Bee Viruses, Colony Health, and Antiviral Defense
Proceedings, 2020 Honey bee colony losses are influenced by multiple abiotic and biotic factors, including viruses. To investigate the effects of RNA viruses on honey bees, we infected bees with a model virus (Sindbis-GFP) in the presence or absence of double-stranded RNA
Katie F. Daughenbaugh +4 more
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Defense Mechanisms against Viral Infection in Drosophila: RNAi and Non-RNAi
Viruses, 2018 RNAi is considered a major antiviral defense mechanism in insects, but its relative importance as compared to other antiviral pathways has not been evaluated comprehensively.
Luc Swevers, Jisheng Liu, Guy Smagghe
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Scientific Reports, 2017 Recent high annual losses of honey bee colonies are associated with many factors, including RNA virus infections. Honey bee antiviral responses include RNA interference and immune pathway activation, but their relative roles in antiviral defense are not ...
Laura M. Brutscher +2 more
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Molecular Plant-Microbe Interactions, 2003 RNA-dependent RNA polymerases (RdRPs) have been implicated in posttranscriptional gene silencing (PTGS) and antiviral defense. An Arabidopsis RdRP (SDE1/SGS2) has been previously shown to be required for transgene-induced PTGS but has no general role in ...
Diqiu Yu +3 more
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