Results 11 to 20 of about 4,215,496 (299)
How to use COVID-19 antiviral drugs in patients with chronic kidney disease
Frontiers in Pharmacology, 2023 Antiviral drugs such as Remdesivir (Veklury), Nirmatrelvir with Ritonavir (Paxlovid), Azvudine, and Molnupiravir (Lagevrio) can reduce the risk for severe and fatal Coronavirus Disease (COVID)-19.
Ajinath Kale +4 more
semanticscholar +1 more source
Antiviral drugs and antiviral drug resistance [PDF]
Current Opinion in Virology, 2011 Antiviral drugs and antiviral drug resistance can be matters of life and death for patients suffering from viral infections. They also can be valuable tools for understanding virus biology and biochemistry. Triumphs of antiviral therapy include acyclovir to treat genital herpes [1–4], triple combination chemotherapy for AIDS [5,6], and, quite recently,
Donald M, Coen, Richard J, Whitley
openaire +2 more sources
Validation of the SCID-hu Thy/Liv mouse model with four classes of licensed antiretrovirals. [PDF]
, 2007 BackgroundThe SCID-hu Thy/Liv mouse model of HIV-1 infection is a useful platform for the preclinical evaluation of antiviral efficacy in vivo.
A Adachi +67 more
core +8 more sources
Development and Effects of Influenza Antiviral Drugs
Molecules, 2021 Influenza virus is a highly contagious zoonotic respiratory disease that causes seasonal outbreaks each year and unpredictable pandemics occasionally with high morbidity and mortality rates, posing a great threat to public health worldwide.
Hang Yin +6 more
semanticscholar +1 more source
iScience, 2022 Summary: L3MBTL2 is a crucial component of ncPRC1.6 and has been implicated in transcriptional repression and chromatin compaction. However, the repression mechanism of L3MBTL2 and its biological functions are largely undefined.
Hua Huang +8 more
doaj +1 more source
Immunology and Allergy Clinics of North America, 2014 Antiviral drugs used to treat HIV and hepatitis C are common causes of delayed drug hypersensitivities for which many of the more severe reactions have been recently shown to be immunogenetically mediated such as abacavir hypersensitivity where HLA-B(∗)57:01 is now used routinely as a screening test to exclude patients carrying this allele from ...
Milpied-Homsi, B. +2 more
openaire +2 more sources
Cells, 2021 The rapid spread of the virus, the surge in the number of deaths, and the unavailability of specific SARS-CoV-2 drugs thus far necessitate the identification of drugs with anti-COVID-19 activity.
R. Pirzada +4 more
semanticscholar +1 more source
Journal of Integrative Neuroscience, 2022 As a catechol isoquinoline, salsolinol (Sal) is widely distributed in mammalian brains, and is increased in the cerebrospinal fluid (CSF) and urine of Parkinsonian patients. Sal can be metabolized to N-methyl-salsolinol (NM-Sal), an MPP+-like neurotoxin,
Qianqian Xiong +7 more
doaj +1 more source
Cochrane acute respiratory infections group's stakeholder engagement project identified systematic review priority areas [PDF]
, 2018 Objective: Cochrane acute respiratory infections (ARIs) group conducts systematic reviews of the evidence for treatment and prevention of ARIs. We report the results of a prioritization project, aiming to identify highest priority systematic review ...
Clark, Justin +5 more
core +1 more source
Cell & Bioscience, 2021 Autophagy is a conserved degradation process crucial to maintaining the primary function of cellular and organismal metabolism. Impaired autophagy could develop numerous diseases, including cancer, cardiomyopathy, neurodegenerative disorders, and aging ...
Xuechai Chen +6 more
doaj +1 more source