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Epstein–Barr virus (EBV) infects up to 95% of the adult human population, with primary infection typically occurring during childhood and usually asymptomatic. However, EBV can cause infectious mononucleosis in approximately 35–50% cases when infection occurs during adolescence and early adulthood.
Pagano, Joseph S.+2 more
openaire +5 more sources
Neuropsychiatric Effects of Antiviral Drugs [PDF]
The adverse events of antiviral drugs are dose-dependent and often reversible. The nervous system is often affected and to date, many studies have been published regarding the central nervous system toxicity of antiviral agents. They may cause significant neuropsychiatric complications, which range from mild symptoms such as irritability and difficulty
Anastasia Karela+5 more
openaire +3 more sources
Natural and Designed Cyclic Peptides as Potential Antiviral Drugs to Combat Future Coronavirus Outbreaks [PDF]
The COVID-19 pandemic has underscored the need for effective and affordable antiviral drugs. Anthropogenic activities have increased interactions among humans, animals, and wildlife, contributing to the emergence of new and re-emerging viral diseases ...
Hilarie Uwamahoro+13 more
doaj +2 more sources
Repurposed Antiviral Drugs for Covid-19 — Interim WHO Solidarity Trial Results
Background World Health Organization expert groups recommended mortality trials of four repurposed antiviral drugs — remdesivir, hydroxychloroquine, lopinavir, and interferon beta-1a — in patients hospitalized with coronavirus disease 2019 (Covid-19 ...
H. Pan+73 more
semanticscholar +2 more sources
Bacteria exposed to antiviral drugs in vitro can develop multiple resistance mutations that confer cross-resistance to antibiotics. Antiviral drugs are used globally as treatment and prophylaxis for long-term and acute viral infections.
Veronica J. Wallace+3 more
semanticscholar +1 more source
Molnupiravir and Nirmatrelvir-Ritonavir: Oral COVID Antiviral Drugs
At a crucial time with rapid spread of Omicron SARS-CoV-2 virus variant globally, the United States Food and Drug Administration has issued an emergency use authorization for two oral antivirals molnupiravir (>18 years) and nirmatrelvir-ritonavir ...
L. Saravolatz+2 more
semanticscholar +1 more source
How to use COVID-19 antiviral drugs in patients with chronic kidney disease
Antiviral drugs such as Remdesivir (Veklury), Nirmatrelvir with Ritonavir (Paxlovid), Azvudine, and Molnupiravir (Lagevrio) can reduce the risk for severe and fatal Coronavirus Disease (COVID)-19.
Ajinath Kale+4 more
semanticscholar +1 more source
A review: Mechanism of action of antiviral drugs
Antiviral drugs are a class of medicines particularly used for the treatment of viral infections. Drugs that combat viral infections are called antiviral drugs. Viruses are among the major pathogenic agents that cause number of serious diseases in humans,
S. Kausar+9 more
semanticscholar +1 more source
Development and Effects of Influenza Antiviral Drugs
Influenza virus is a highly contagious zoonotic respiratory disease that causes seasonal outbreaks each year and unpredictable pandemics occasionally with high morbidity and mortality rates, posing a great threat to public health worldwide.
Hang Yin+6 more
semanticscholar +1 more source
Autophagy is a conserved degradation process crucial to maintaining the primary function of cellular and organismal metabolism. Impaired autophagy could develop numerous diseases, including cancer, cardiomyopathy, neurodegenerative disorders, and aging ...
Xuechai Chen+6 more
doaj +1 more source