Results 31 to 40 of about 45,720 (293)

Pharmacological validation of the anxiolytic, muscle relaxant and sedative like activities of Capsicum annuum in animal model

Bangladesh Journal of Pharmacology, 2017
The current study deals with anxiolytic, muscle relaxant and sedative like activities of Capsicum annuum in animal models. The crude extract was found safe in acute behavior and toxicity studies.
Muhammad Jawad, Haroon Khan, Samreen Pervez, Saud S. Bawazeer, Tareq Abu-Izneid, Muhammad Saeed, Mohammad A. Kamal   +6 more
doaj   +1 more source

Relationship among psychotic features, benzodiazepine receptor agonists, and rehospitalization in patients with electroconvulsive therapy‐responsive major depressive disorder: A retrospective 2‐year observational study

Neuropsychopharmacology Reports, Volume 42, Issue 4, Page 449-456, December 2022., 2022
Abstract Aim It is controversial whether psychotic features are a risk factor for relapse in patients with electroconvulsive therapy‐responsive major depressive disorder. A recent study reported that benzodiazepine receptor agonists reduce relapse of psychotic depression.
Akise Umakoshi, Masahiro Takeshima, Yu Itoh, Mari Yamamoto, Nana Shibata, Masaya Ogasawara, Naoko Ayabe, Kazuo Mishima   +7 more
wiley   +1 more source

Caffeine facilitates extinction of auditory fear conditioning in rats

Neuropsychopharmacology Reports, Volume 42, Issue 4, Page 521-525, December 2022., 2022
Abstract Caffeine is the most widely consumed psychostimulant drug which could affect learning and memory acting through central adenosine receptors. Although caffeine has been suggested to impair the acquisition and the expression of auditory fear conditioning, its effect on the extinction has not been elucidated. To address this issue, in the present
Takaaki Ozawa, Kodai Kaseda, Yukio Ichitani, Kazuo Yamada   +3 more
wiley   +1 more source

Experimental pharmacological research regarding some new quinazolin-4-ones derivatives

Journal of Mind and Medical Sciences, 2019
A series of new compounds with quinazolin-4-one structure, synthesized by the Pharmaceutical Chemistry Department of the Faculty of Pharmacy of the University of Medicine and Pharmacy “Carol Davila” Bucharest, was studied.
Cornel Chiriță, Emil Ștefănescu, Cristina Elena Zbârcea, Simona Negreș, Mihaela Bratu, Diana Camelia Nuță, Carmen Limban, Ileana Cornelia Chiriță, Cristina Daniela Marineci   +8 more
doaj   +1 more source

The pharmacology of anxiolytics [PDF]

South African Family Practice, 2010
AbstractGiven that anxiety disorders are common and chronic and often co-morbid with both medical and psychiatric conditions, effective and safe anxiolytic drugs are in great demand. Serotonergic agents, in particular the selective serotonin reuptake inhibitors and serotonin and noradrenaline reuptake inhibitors, have an established track record for ...
openaire   +2 more sources

The Effect of Anxiolytics on Tinnitus

Journal of Clinical Medicine, 2023
Tinnitus is a perceptual disorder in which sound is perceived by the patient in the absence of an external or internal acoustic stimulation [...]
George Psillas, Chrysoula Vlachou
openaire   +2 more sources

Development of individual fitness score for conformity of prescriptions to the “Guidelines For Pharmacological Therapy of Schizophrenia”

Neuropsychopharmacology Reports, Volume 42, Issue 4, Page 502-509, December 2022., 2022
Abstract Aims The Guidelines for the Pharmacotherapy of Schizophrenia were established to improve the quality of medical care, and the EGUIDE project was conducted to train clinicians on guideline usage. A quality indicator (QI) was established to measure the prevalence of the guidelines, and a survey was conducted, which revealed a gap between the ...
Ken Inada, Kentaro Fukumoto, Naomi Hasegawa, Yuka Yasuda, Hisashi Yamada, Hikaru Hori, Kayo Ichihashi, Hitoshi Iida, Kazutaka Ohi, Hiroyuki Muraoka, Fumitoshi Kodaka, Kenta Ide, Naoki Hashimoto, Jun‐ichi Iga, Kazuyoshi Ogasawara, Kiyokazu Atake, Yoshikazu Takaesu, Tatsuya Nagasawa, Hiroshi Komatsu, Tsuyoshi Okada, Ryuji Furihata, Mikio Kido, Saya Kikuchi, Chika Kubota, Manabu Makinodan, Shinichiro Ochi, Masahiro Takeshima, Hirotaka Yamagata, Junya Matsumoto, Kenichiro Miura, Masahide Usami, Taishiro Kishimoto, Toshiaki Onitsuka, Eiichi Katsumoto, Akitoyo Hishimoto, Shusuke Numata, Norio Yasui‐Furukori, Koichiro Watanabe, Ryota Hashimoto   +38 more
wiley   +1 more source

Anxiolytic-like effects of 4-phenyl-2-trichloromethyl-3H-1,5-benzodiazepine hydrogen sulfate in mice

Brazilian Journal of Medical and Biological Research, 2000
The pharmacological effects of 4-phenyl-2-trichloromethyl-3H-1,5-benzodiazepine hydrogen sulfate (PTMB), a novel synthetic benzodiazepine, were examined in mice.
M.A. Rubin, C.A. Albach, D.B. Berlese, H.G. Bonacorso, S.R.T. Bittencourt, C.M.T. Queiroz, A.E. Maixner, C.F. Mello   +7 more
doaj   +1 more source

Structure-Dependent Activity of Natural GABA(A) Receptor Modulators

Molecules, 2018
GABA(A) receptors are ligand-gated ion channels consisting of five subunits from eight subfamilies, each assembled in four hydrophobic transmembrane domains.
Serhat Sezai Çiçek
doaj   +1 more source

Role of private prescriptions in the long‐term use of benzodiazepines and Z‐drugs: A patient‐related follow‐up study

Pharmacoepidemiology and Drug Safety, Volume 32, Issue 1, Page 60-65, January 2023., 2023
Abstract Purpose To analyse (1) how often patients insured under the statutory health insurance (SHI) scheme received repeated prescriptions for benzodiazepines or Z‐drugs as private prescriptions and (2) how often doctors switched from SHI prescriptions to private prescriptions and vice versa when issuing repeat prescriptions.
Thomas Grimmsmann, Wolfgang Himmel
wiley   +1 more source