Results 41 to 50 of about 89,248 (335)

Environmental manipulations generate bidirectional shifts in both behavior and gene regulation in a crossbred mouse model of extremes in trait anxiety [PDF]

open access: yes, 2014
Although gene-environment interactions are known to significantly influence psychopathology related disease states, only few animal models cover both the genetic background and environmental manipulations.
Chekmareva, N.   +5 more
core   +2 more sources

Development and acceptability of a decision aid for anxiety disorder considering discontinuation of benzodiazepine anxiolytic

open access: yesFrontiers in Psychiatry, 2023
AimWe aimed to develop a decision aid (DA) for individuals with anxiety disorders who consider tapering benzodiazepine (BZD) anxiolytics, and if tapering, tapering BZD anxiolytics with or without cognitive behavioral therapy (CBT) for anxiety.
Yumi Aoki   +11 more
doaj   +1 more source

Cardiovascular and cortisol reactions to acute psychological stress and cognitive ability in the Dutch Famine Birth Cohort Study [PDF]

open access: yes, 2011
Objective: Recently, in analyses of data from a large community sample, negative cross-sectional and prospective associations between cardiac stress reactivity and obesity were observed.
al'Absi   +67 more
core   +1 more source

The efficacy of trazodone in reducing stress related behaviours in hospitalised dogs or dogs confined postsurgery

open access: yesVeterinary Evidence, 2023
PICO question In hospitalised dogs or dogs confined postsurgery, does administration of trazodone reduce stress related behaviours compared to no treatment with trazodone?   Clinical bottom line Category of research Treatment. Number and type
Lara Dillon
doaj   +1 more source

Characteristics of the basal psychoautonomous indicators in patients after coronary artery stent placement at various stages of rehabilitation

open access: yesAlʹmanah Kliničeskoj Mediciny, 2023
Background: Clinically significant psychoautonomous syndrome, along with other modifiable factors (obesity, dyslipidemia, low physical activity, smoking, arterial hypertension, etc.) increases the risk of development and progression of coronary artery ...
Ruslan A. Mirzoev   +2 more
doaj   +1 more source

Behavioural inhibition and valuation of gain/loss are neurally distinct from approach/withdrawal [PDF]

open access: yes, 2019
Gain or omission/termination of loss produces approach; while loss or omission/termination of gain produces withdrawal. Control of approach/withdrawal motivation is distinct from valuation of gain/loss and does not entail learning – making “reward” and ...
Corr, P. J., McNaughton, N.
core   +1 more source

TSPO: kaleidoscopic 18-kDa amid biochemical pharmacology, control and targeting of mitochondria [PDF]

open access: yes, 2016
The 18-kDa translocator protein (TSPO) localizes in the outer mitochondrial membrane (OMM) of cells and is readily up-regulated under various pathological conditions such as cancer, inflammation, mechanical lesions and neurological diseases. Able to bind
Aghazadeh   +189 more
core   +1 more source

Neuropharmacological and Antidiarrheal Potentials of Duabanga grandiflora (DC.) Walp. Stem Bark and Prospective Ligand–Receptor Interactions of Its Bioactive Lead Molecules

open access: yesCurrent Issues in Molecular Biology, 2022
Duabanga grandiflora (DC.) Walp. is an ethnomedicinally significant plant used to treat various illnesses, but there is little scientific evidence to support its use.
Israt Jahan   +8 more
doaj   +1 more source

Cognitive facilitation following intentional odor exposure [PDF]

open access: yes, 2011
This paper reviews evidence that, in addition to incidental olfactory pollutants, intentional odor delivery can impact cognitive operations both positively and negatively.
Aggleton   +98 more
core   +4 more sources

A Machine‐Learning Approach Identifies Rejuvenating Interventions in the Human Brain

open access: yesAdvanced Science, EarlyView.
Rising life expectancy increases the incidence of age‐related neurodegeneration. Reverting brain aging through effective rejuvenation strategies constitutes a promising strategy to counteract these disorders and restore brain function. This study uses a brain‐specific transcriptional aging clock to screen over 43 000 perturbation profiles, identifying ...
Guillem Santamaria   +5 more
wiley   +1 more source

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