Results 41 to 50 of about 73,505 (352)

Identification of a Novel Neuropeptide S Receptor Antagonist Scaffold Based on the SHA-68 Core

Pharmaceuticals, 2021
Activation of the neuropeptide S receptor (NPSR) system has been shown to produce anxiolytic-like actions, arousal, and enhance memory consolidation, whereas blockade of the NPSR has been shown to reduce relapse to substances of abuse and duration of ...
Allison Zarkin, Rajwana Jahan, Rajendra Uprety, Yanan Zhang, Charles McElhinny, Rodney Snyder, Elaine Gay, Gabriel Jewula, Heather Bool, Stewart D Clark, Scott Runyon   +10 more
doaj   +1 more source

Increasing Adiponectin Signaling by Sub-Chronic AdipoRon Treatment Elicits Antidepressant- and Anxiolytic-Like Effects Independent of Changes in Hippocampal Plasticity

Biomedicines, 2023
(1) Background: Adiponectin is an adipocyte-secreted hormone that has antidepressant- and anxiolytic-like effects in preclinical studies. Here, we investigated the antidepressant- and anxiolytic-like effects of sub-chronic treatment with AdipoRon, an ...
Douglas A. Formolo, Thomas H. Lee, Jiasui Yu, Kangguang Lin, Gang Chen, Georg S. Kranz, Suk-Yu Yau   +6 more
doaj   +1 more source

Anxiolytic effects of the flavonoid luteolin in a mouse model of acute colitis

Molecular Brain, 2019
Anxiety related disorders commonly occur in association with major depressive disorder (MDD) in individuals suffering from peripheral inflammation, with a higher prevalence among IBS patients.
V. M. Gadotti, G. Zamponi
semanticscholar   +1 more source

Anxiolytic, Antidepression, and Memory-Enhancing Effects of the Novel Instant Soup RJ6601 in the Middle-Aged of Female Rats

Foods
Due to the health benefits of polyphenols and dietary fiber in combating mental disorders, we hypothesized that a polyphenol- and dietary fiber-enriched soup (RJ6601) would improve mental wellness in a rat model of middle-aged women.
Rujikan Chaisanam, Jintanaporn Wattanathorn, Wipawee Thukham-mee, Nawanant Piyavhatkul, Pongsatorn Paholpak   +4 more
doaj   +1 more source

Effects of psychotropic agents on extinction of lever-press avoidance in a rat model of anxiety vulnerability

Frontiers in Behavioral Neuroscience, 2014
Avoidance and its perseveration represent key features of anxiety disorders. Both pharmacological and behavioral approaches (i.e. anxiolytics and extinction therapy) have been utilized to modulate avoidance behavior in patients.
Xilu eJiao, Xilu eJiao, Xilu eJiao, Kevin D. Beck, Kevin D. Beck, Kevin D. Beck, Amanda L. Stewarts, Ian M. Smith, Ian M. Smith, Catherine E. Myers, Catherine E. Myers, Catherine E. Myers, Richard J Servatius, Richard J Servatius, Richard J Servatius, Kevin C.H. Pang, Kevin C.H. Pang, Kevin C.H. Pang   +17 more
doaj   +1 more source

GC-MS Phytochemical Profiling, Pharmacological Properties, and In Silico Studies of Chukrasia velutina Leaves: A Novel Source for Bioactive Agents

Molecules, 2020
Chukrasia velutina is a local medicinal plant commonly known as chikrassy in Bangladesh, India, China, and other South Asian countries. The leaves, bark, and seeds are vastly used as herbal medicine for fever and diarrhea, and its leaves essential oils ...
Israt Jahan, Marzia Rahman Tona, Sanjida Sharmin, Mohammed Aktar Sayeed, Fatamatuz Zuhura Tania, Arkajyoti Paul, Md. Nazim Uddin Chy, Ahmed Rakib, Talha Bin Emran, Jesus Simal-Gandara   +9 more
doaj   +1 more source

Differences in the effects of anxiolytics bromodihydrochlorophenylbenzodiazepine and fabomotizole in patients with anxiety disorders in dependence on their individually-typological features

European Psychiatry, 2022
Introduction Personalized approach in drug therapy is an essential line of modern psychiatry. Experimental and clinical studies of anxiolytics have shown differences in drug effects in dependence on genetically determined reactions to stress and ...
O. Dorofeeva, M. Metlina
doaj   +1 more source

Antibiotic yields anxiolytic [PDF]

Nature Reviews Neuroscience, 2004
Suzanne Farley
openalex   +3 more sources

Central amygdala circuit dynamics underlying the benzodiazepine anxiolytic effect

Molecular Psychiatry, 2018
Benzodiazepines (BZDs) have been a standard treatment for anxiety disorders for decades, but the neuronal circuit interactions mediating their anxiolytic effect remain largely unknown.
J. Griessner, Manuel Pasieka, Vincent Böhm, Florian Grössl, J. Kaczanowska, Pinelopi Pliota, Dominic Kargl, Barbara Werner, N. Kaouane, S. Strobelt, S. Kreitz, A. Hess, W. Haubensak   +12 more
semanticscholar   +1 more source

Erratum to: Comparing the effectiveness of clomipramine and fluoxetine in dogs with anxiety-related behaviours

Veterinary Evidence
The original article was published in Veterinary Evidence Vol 9, Issue 1 (2024): https://doi.org/10.18849/ve.v9i1.679 In the original version of the article the contributions of one of the authors, Christopher Minami, were listed as "Investigation ...
Olivia Williamson, Valery Varela, Christopher Minami, Juliana Tom, Elizabeth Powell, Jeffrey W. Norris   +5 more
doaj   +1 more source