β-aminopropionitrile-induced thoracic aortopathy is refractory to cilostazol and sildenafil in mice. [PDF]
PLoS ONEThoracic aortopathies are life-threatening diseases including aneurysm, dissection, and rupture. Cilostazol, a phosphodiesterase (PDE) 3 inhibitor, and sildenafil, a PDE5 inhibitor, have been used clinically for peripheral arterial disease and erectile ...
Samuel C Tyagi +7 more
doaj +4 more sources
Aortic Valve Dysfunction and Aortopathy Based on the Presence of Raphe in Patients with Bicuspid Aortic Valve Disease [PDF]
Journal of Cardiovascular Development and Disease, 2023 (1) Background: To identify the association between the presence or absence of a raphe and aortic valve dysfunction, as well as the presence of aortopathy in patients with a bicuspid aortic valve (BAV); (2) Methods: This retrospective study enrolled 312 ...
Yu Zhang +4 more
doaj +2 more sources
Cardiovascular Imaging in Pregnancy: Valvulopathy, Hypertrophic Cardiomyopathy, and Aortopathy [PDF]
Frontiers in Cardiovascular Medicine, 2022 Pregnancy is associated with profound hemodynamic changes that are particularly impactful in patients with underlying cardiovascular disease. Management of pregnant women with cardiovascular disease requires careful evaluation that considers the well ...
Haneen Ismail +2 more
doaj +2 more sources
Exploring ethnic differences in the perioperative course of thoracic aortopathy [PDF]
Frontiers in Cardiovascular MedicineBackgroundIn patients with thoracic aortopathy post-operative recovery can be complicated by a lack of consistent, clear communication and guidance. Despite the growing recognition of these challenges, the specific needs of patients undergoing aortic ...
Nora Bacour +7 more
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Aortopathy in Tetralogy of Fallot – Insights from a single-center observational study [PDF]
Annals of Pediatric CardiologyObjective: The objective of this study was to assess the presence of aortopathy on follow-up in operated and unoperated adolescent and adult patients with Tetralogy of Fallot (TOF) and to identify the various associated factors.
Usnish Adhikari +3 more
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Evolving Surgical Approaches to Bicuspid Aortic Valve Associated Aortopathy [PDF]
Frontiers in Cardiovascular Medicine, 2019 Bicuspid aortic valve (BAV) is the most common congenital cardiac pathology which results from the fusion of two adjacent aortic valve cusps. It is associated with dilatation of the aorta, known as bicuspid valve-associated aortopathy or bicuspid ...
Ali Fatehi Hassanabad +4 more
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Emerging imaging and circulating biomarkers in relation to underlying mechanisms in Bicuspid Aortic Valve aortopathy [PDF]
International Journal of Cardiology: Heart & VasculatureBicuspid Aortic Valve (BAV) is the most prevalent congenital heart defect with an autosomal dominant inheritance. With up to 2% of the general population affected by the condition, mortality remains high likely due to the development of aortopathy which ...
Hamza M Ahmad +4 more
doaj +2 more sources
Aortopathy associated with bicuspid aortic valve: advances in clinical and hemodynamics research [PDF]
Frontiers in PhysiologyHaving a bicuspid aortic valve (BAV) is the most common congenital heart disease, affecting 0.5%–2% of the population, with significant heterogeneity in clinical presentation, complications, and outcomes.
Minghui Yang +4 more
doaj +2 more sources
Connective tissue disorder and high risk pregnancy: a case series with personalised external aortic root support (PEARS) [PDF]
Nature CommunicationsAortopathy including Marfan (MFS) and Loeys-Dietz syndrome (LDS) poses a high risk of aortic dissection, particularly during pregnancy and the puerperium.
Claudia Montanaro +12 more
doaj +2 more sources
Vertebral artery tortuosity in Turner syndrome: is tortuosity a component of the aortopathy phenotype? [PDF]
, 2014 Cory V Noel +7 more
core +6 more sources