Results 1 to 10 of about 2,749 (160)
β-aminopropionitrile-induced thoracic aortopathy is refractory to cilostazol and sildenafil in mice. [PDF]
PLoS ONEThoracic aortopathies are life-threatening diseases including aneurysm, dissection, and rupture. Cilostazol, a phosphodiesterase (PDE) 3 inhibitor, and sildenafil, a PDE5 inhibitor, have been used clinically for peripheral arterial disease and erectile ...
Samuel C Tyagi +7 more
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Exploring ethnic differences in the perioperative course of thoracic aortopathy [PDF]
Frontiers in Cardiovascular MedicineBackgroundIn patients with thoracic aortopathy post-operative recovery can be complicated by a lack of consistent, clear communication and guidance. Despite the growing recognition of these challenges, the specific needs of patients undergoing aortic ...
Nora Bacour +7 more
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Aortopathy in Tetralogy of Fallot – Insights from a single-center observational study [PDF]
Annals of Pediatric CardiologyObjective: The objective of this study was to assess the presence of aortopathy on follow-up in operated and unoperated adolescent and adult patients with Tetralogy of Fallot (TOF) and to identify the various associated factors.
Usnish Adhikari +3 more
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Emerging imaging and circulating biomarkers in relation to underlying mechanisms in Bicuspid Aortic Valve aortopathy [PDF]
International Journal of Cardiology: Heart & VasculatureBicuspid Aortic Valve (BAV) is the most prevalent congenital heart defect with an autosomal dominant inheritance. With up to 2% of the general population affected by the condition, mortality remains high likely due to the development of aortopathy which ...
Hamza M Ahmad +4 more
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Connective tissue disorder and high risk pregnancy: a case series with personalised external aortic root support (PEARS) [PDF]
Nature CommunicationsAortopathy including Marfan (MFS) and Loeys-Dietz syndrome (LDS) poses a high risk of aortic dissection, particularly during pregnancy and the puerperium.
Claudia Montanaro +12 more
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Aortopathy associated with bicuspid aortic valve: advances in clinical and hemodynamics research [PDF]
Frontiers in PhysiologyHaving a bicuspid aortic valve (BAV) is the most common congenital heart disease, affecting 0.5%–2% of the population, with significant heterogeneity in clinical presentation, complications, and outcomes.
Minghui Yang +4 more
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Frontiers in Cardiovascular Medicine, 2021 Background: Using echocardiographic surveillance, many patients are diagnosed with bicuspid aortic valve (BAV) without significant valve dysfunction. Limited data are available regarding the progression and outcomes of non-dysfunctional BAV.Methods and ...
Shinjeong Song +5 more
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Long-term outcomes in heritable thoracic aortic disease
Frontiers in Cardiovascular Medicine, 2022 Heritable aortic aneurysm is an increasingly recognized cause of morbidity and mortality. Whilst Marfan syndrome (MFS) is well-known, the clinical presentation and prognosis of more newly described genetic syndromes is less familiar to clinicians.
Elizabeth N. Robertson +7 more
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Clinical implications of the biomechanics of bicuspid aortic valve and bicuspid aortopathy
Frontiers in Cardiovascular Medicine, 2022 Bicuspid aortic valve (BAV), which affects up to 2% of the general population, results from the abnormal fusion of the cusps of the aortic valve. Patients with BAV are at a higher risk for developing aortic dilatation, a condition known as bicuspid ...
Ali Fatehi Hassanabad +9 more
doaj +1 more source
Journal of Cardiothoracic Surgery, 2020 Background Primary and secondary aortopathy are frequently encountered in patients with congenital heart disease. The aim of this study is to present our experience and the incidence of primary and secondary adult CHD-associated aortopathy.
Ingrid Schusterova +4 more
doaj +1 more source