Results 11 to 20 of about 2,749 (160)
Aortopathy – A surgical pathology experience
Indian Journal of Pathology and MicrobiologyBackground: Aortopathy is a non-inflammatory and non-atherosclerotic disease of aorta that results from significant ‘degenerative’ changes in the media. This often leads to thoracic aortic aneurysms and/or dissections in young individuals.
Pradeep Vaideeswar, Sujit Udayaravi
doaj +3 more sources
MiR-145 expression and rare NOTCH1 variants in bicuspid aortic valve-associated aortopathy. [PDF]
PLoS ONE, 2018 MicroRNAs (miRNAs) may serve as elegant tool to improve risk stratification in bicuspid aortic valve (BAV)-associated aortopathy. However, the exact pathogenetic pathway by which miRNAs impact aortopathy progression is unknown.
Evaldas Girdauskas +6 more
doaj +1 more source
Frontiers in Cardiovascular Medicine, 2023 PurposeCurrent intervention guidelines for bicuspid aortic valve (BAV) associated ascending aorta (AAo) dilatation are suboptimal predictors of clinical outcome.
Jiaxing Jason Qin +10 more
doaj +1 more source
TIMP3 and TIMP1 are risk genes for bicuspid aortic valve and aortopathy in Turner syndrome. [PDF]
PLoS Genetics, 2018 Turner syndrome is caused by complete or partial loss of the second sex chromosome, occurring in ~1 in 2,000 female births. There is a greatly increased incidence of aortopathy of unknown etiology, including bicuspid aortic valve (BAV), thoracic aortic ...
Holly Corbitt +7 more
doaj +1 more source
JTCVS Open, 2023 Objective: Genetic aortopathy, if left untreated, leads to aortic catastrophe in most affected individuals. We sought to determine the genetic mutation patterns and detection rates in patients with aortopathy and their families with a systematic ...
Jihoon Kim, MD, PhD +6 more
doaj +1 more source
A Novel Human Biospecimen Repository for Clinical and Molecular Investigation of Thoracic Aortopathy
Cardiogenetics, 2021 Thoracic aortic aneurysm (TAA) is a heritable aortopathy with significant morbidity and mortality, affecting children and adults. Genetic causes, pathobiological mechanisms, and prognostic markers are incompletely understood.
Courtney E. Vujakovich +1 more
doaj +1 more source
Frontiers in Cardiovascular Medicine, 2022 Bicuspid aortopathy occurs in approximately 50% of patients with bicuspid aortic valve (BAV), the most prevalent congenital cardiac malformation. Although different molecular players and etiological factors (genetic and hemodynamic) have been suggested ...
María Teresa Soto-Navarrete +21 more
doaj +1 more source
Evolving Surgical Approaches to Bicuspid Aortic Valve Associated Aortopathy
Frontiers in Cardiovascular Medicine, 2019 Bicuspid aortic valve (BAV) is the most common congenital cardiac pathology which results from the fusion of two adjacent aortic valve cusps. It is associated with dilatation of the aorta, known as bicuspid valve-associated aortopathy or bicuspid ...
Ali Fatehi Hassanabad +4 more
doaj +1 more source
Indian Journal of Sexually Transmitted Diseases and AIDS, 2010 We report a case of 38-year-old male, who presented with a large pulsatile swelling on the left side of the anterior chest wall of 4 months' duration with a gradual increase in size. He gave history of sexual promiscuity in the form of unprotected sexual intercourse prior to his marriage in his early 20s. He also gave a history of ulceration on coronal
Madke, Bhushan Sevakram +5 more
openaire +3 more sources
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2017 BackgroundMarfan syndrome (MFS) is caused by mutations in the gene encoding fibrillin‐1 (FBN1); however, the mechanisms through which fibrillin‐1 deficiency causes MFS‐associated aortopathy are uncertain. Recently, attention was focused on the hypothesis
Hao Wei +7 more
doaj +1 more source