Results 11 to 20 of about 6,089 (248)

Aortopathy – A surgical pathology experience

Indian Journal of Pathology and Microbiology
Background: Aortopathy is a non-inflammatory and non-atherosclerotic disease of aorta that results from significant ‘degenerative’ changes in the media. This often leads to thoracic aortic aneurysms and/or dissections in young individuals.
Pradeep Vaideeswar, Sujit Udayaravi
doaj   +3 more sources

Embryological Divergence and Molecular Mechanisms in Thoracic and Abdominal Aortic Aneurysms: Bridging Developmental Biology and Clinical Insights [PDF]

Biomolecules
Aortic aneurysms are complex, predominantly asymptomatic vascular diseases with distinct incidence patterns depending on anatomical localisation. The incidence of thoracic aortic aneurysms (TAAs) has moderately increased, whereas that of abdominal aortic
Mathias Van Hemelrijck, Petar Risteski, Laura Rings, Milan Milojevic, Héctor Rodríguez Cetina Biefer, Omer Dzemali   +5 more
doaj   +2 more sources

Progression and Outcomes of Non-dysfunctional Bicuspid Aortic Valve: Longitudinal Data From a Large Korean Bicuspid Aortic Valve Registry

Frontiers in Cardiovascular Medicine, 2021
Background: Using echocardiographic surveillance, many patients are diagnosed with bicuspid aortic valve (BAV) without significant valve dysfunction. Limited data are available regarding the progression and outcomes of non-dysfunctional BAV.Methods and ...
Shinjeong Song, Jiwon Seo, Iksung Cho, Geu-Ru Hong, Jong-Won Ha, Chi Young Shim   +5 more
doaj   +1 more source

Long-term outcomes in heritable thoracic aortic disease

Frontiers in Cardiovascular Medicine, 2022
Heritable aortic aneurysm is an increasingly recognized cause of morbidity and mortality. Whilst Marfan syndrome (MFS) is well-known, the clinical presentation and prognosis of more newly described genetic syndromes is less familiar to clinicians.
Elizabeth N. Robertson, Elizabeth N. Robertson, Paul G. Bannon, Paul G. Bannon, Paul G. Bannon, Richmond W. Jeremy, Richmond W. Jeremy, Richmond W. Jeremy   +7 more
doaj   +1 more source

Clinical implications of the biomechanics of bicuspid aortic valve and bicuspid aortopathy

Frontiers in Cardiovascular Medicine, 2022
Bicuspid aortic valve (BAV), which affects up to 2% of the general population, results from the abnormal fusion of the cusps of the aortic valve. Patients with BAV are at a higher risk for developing aortic dilatation, a condition known as bicuspid ...
Ali Fatehi Hassanabad, Melissa A. King, Elena Di Martino, Elena Di Martino, Elena Di Martino, Paul W. M. Fedak, Julio Garcia, Julio Garcia, Julio Garcia, Julio Garcia   +9 more
doaj   +1 more source

A Multidisciplinary Aortopathy Clinic: The McGill Experience. [PDF]

CJC Open
Kodaira M, Lachapelle K, Leask RL, Bates K, Grossman Y, Guerrero-Chalela CE, Kennedy L, Thanassoulis G, Steinmetz OK, MacKenzie K, Pressacco J, Engert JC, Therrien J.   +12 more
europepmc   +3 more sources

Primary and secondary aortopathy associated with adult congenital heart disease - retrospective study

Journal of Cardiothoracic Surgery, 2020
Background Primary and secondary aortopathy are frequently encountered in patients with congenital heart disease. The aim of this study is to present our experience and the incidence of primary and secondary adult CHD-associated aortopathy.
Ingrid Schusterova, Alžbeta Banovcinova, Marianna Vachalcova, Marta Jakubova, Panagiotis Artemiou   +4 more
doaj   +1 more source

MiR-145 expression and rare NOTCH1 variants in bicuspid aortic valve-associated aortopathy. [PDF]

PLoS ONE, 2018
MicroRNAs (miRNAs) may serve as elegant tool to improve risk stratification in bicuspid aortic valve (BAV)-associated aortopathy. However, the exact pathogenetic pathway by which miRNAs impact aortopathy progression is unknown.
Evaldas Girdauskas, Johannes Petersen, Niklas Neumann, Martin Ungelenk, Ingo Kurth, Hermann Reichenspurner, Tanja Zeller   +6 more
doaj   +1 more source

4D-flow MRI derived wall shear stress for the risk stratification of bicuspid aortic valve aortopathy: A systematic review

Frontiers in Cardiovascular Medicine, 2023
PurposeCurrent intervention guidelines for bicuspid aortic valve (BAV) associated ascending aorta (AAo) dilatation are suboptimal predictors of clinical outcome.
Jiaxing Jason Qin, Jiaxing Jason Qin, Peyman Obeidy, Peyman Obeidy, Mustafa Gok, Mustafa Gok, Mustafa Gok, Alireza Gholipour, Alireza Gholipour, Stuart M. Grieve, Stuart M. Grieve   +10 more
doaj   +1 more source

TIMP3 and TIMP1 are risk genes for bicuspid aortic valve and aortopathy in Turner syndrome. [PDF]

PLoS Genetics, 2018
Turner syndrome is caused by complete or partial loss of the second sex chromosome, occurring in ~1 in 2,000 female births. There is a greatly increased incidence of aortopathy of unknown etiology, including bicuspid aortic valve (BAV), thoracic aortic ...
Holly Corbitt, Shaine A Morris, Claus H Gravholt, Kristian H Mortensen, Rebecca Tippner-Hedges, Michael Silberbach, Cheryl L Maslen, GenTAC Registry Investigators   +7 more
doaj   +1 more source