Results 21 to 30 of about 2,749 (160)
Novel Approaches for BAV Aortopathy Prediction—Is There a Need for Cohort Studies and Biomarkers?
Biomolecules, 2018 Bicuspid aortic valve (BAV) disease is the most common congenital malformation of the human heart with a prevalence of 1–2% in the general population.
Evaldas Girdauskas +7 more
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Genetics of Heritable Thoracic Aortic Disease
Cardiogenetics, 2022 Genetic testing plays an increasing diagnostic and prognostic role in the management of patients with heritable thoracic aortic disease (HTAD). The identification of a specific variant can establish or confirm the diagnosis of syndromic HTAD, dictate ...
Efstathios Papatheodorou +2 more
doaj +1 more source
Frontiers in Physiology, 2017 Bicuspid aortic valve (BAV) is a common congenital cardiac malformation affecting 1–2% of people. BAV results from fusion of two adjacent aortic valve cusps, and is associated with dilatation of the aorta, known as bicuspid valve associated aortopathy ...
Ali Fatehi Hassanabad +8 more
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DNA Methylation Analysis of Turner Syndrome BAV
Frontiers in Genetics, 2022 Turner Syndrome (TS) is a rare cytogenetic disorder caused by the complete loss or structural variation of the second sex chromosome. The most common cause of early mortality in TS results from a high incidence of left-sided congenital heart defects ...
Jacob Gutierrez +8 more
doaj +1 more source
Journal of Cardiovascular Development and Disease, 2023 (1) Background: To identify the association between the presence or absence of a raphe and aortic valve dysfunction, as well as the presence of aortopathy in patients with a bicuspid aortic valve (BAV); (2) Methods: This retrospective study enrolled 312 ...
Yu Zhang +4 more
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Bicuspid aortic valve associated aortopathy: a genetic disease?
Cardiogenetics, 2015 The present paper briefly reviews the literature supporting the pathogenetic importance of hemodynamics in the development of bicuspid aortic valve-associated aortopathy.
Ciro Bancone +2 more
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Aortic Dilatation in Patients With Bicuspid Aortic Valve
Frontiers in Physiology, 2021 Bicuspid aortic valve (BAV) is the most common congenital cardiac abnormality. BAV aortic dilatation is associated with an increased risk of adverse aortic events and represents a potentially lethal disease and hence a considerable medical burden.
Jing Wang +17 more
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Evidence of Aortopathy in Mice with Haploinsufficiency of Notch1 in Nos3-Null Background
Journal of Cardiovascular Development and Disease, 2015 Thoracic aortic aneurysms (TAA) are a significant cause of morbidity and mortality in humans. While the exact etiology is unknown, genetic factors play an important role.
Sara N. Koenig +4 more
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Surgical management of the aortic arch in patients with inherited aortopathy
Frontiers in Cardiovascular Medicine, 2022 Surgical management of the aortic root and ascending aorta has seen an evolution over the past 50 years. Despite the widely available guidelines for management of the aortic root and ascending aorta, including in those with connective tissue disease and ...
Gianluca Lucchese, Rajdeep Bilkhu
doaj +1 more source
Reviews in Cardiovascular Medicine, 2023 Bicuspid Aortic Valves (BAV) are associated with an increased incidence of thoracic aortic aneurysms (TAA). TAA are a common aortic pathology characterized by enlargement of the aortic root and/or ascending aorta, and may become life threatening when ...
Habib Jabagi +7 more
doaj +1 more source