Results 51 to 60 of about 6,089 (248)

Ventricular‐Vascular Coupling in Marfan and Non‐Marfan Aortopathies [PDF]

, 2016
Background: Marfan syndrome (MFS) and familial non–syndromal thoracic aortic aneurysm and dissection (ns‐TAAD) are genetic aortopathies causing aortic dilatation with increased aortic stiffness.
Hambly, Brett, Jeremy, Richmond, Loeper, Farina, Lu, Yaxin, Oosterhof, Jantine, Robertson, Elizabeth, van den Dorpel, Mark, van der Linde, Denise   +7 more
core   +1 more source

Obstetric considerations for aortopathy in pregnancy

Annals of Cardiothoracic Surgery, 2023
Aortic dissection (AD) associated with pregnancy can have catastrophic consequences for the mother and/or fetus. AD occurs in 4-5 per 1,000,000 pregnancies and, despite its rarity, is the third most frequent maternal cardiovascular cause of death. AD associated with pregnancy is most likely to occur in the third trimester or postpartum period.
Whelan, Anna R., Ringel, Myles E., Shalhub, Sherene, Russo, Melissa L.   +3 more
openaire   +2 more sources

In vitro characterization of hemodynamics in bicuspid aortic valves: The impact of valve and ascending aortic morphologies

Magnetic Resonance in Medicine, Volume 95, Issue 1, Page 411-429, January 2026.
Abstract Purpose This study investigated the effect of bicuspid aortic valve (BAV) morphology and ascending aortic curvature (AAAc) bending angles on aortic hemodynamics, focusing on transvalvular jets and secondary helical flows that contribute to systolic hemodynamic stress linked to aortic complications.
Kaoru Hattori, Natsuki Nakama, Jumpei Takada, Michinobu Nagao, Yasuhiro Goto, Hiroshi Niinami, Kiyotaka Iwasaki   +6 more
wiley   +1 more source

Cardiovascular genetic counselor decision making about discussing life insurance with patients

Journal of Genetic Counseling, Volume 34, Issue 6, December 2025.
Abstract Genetic counselors (GCs) educate patients about the benefits, risks, and limitations of genetic testing. The regulatory environment governing the use of genetic data in life insurance is not uniform internationally or within the United States (US).
Sara Cherny, Sarah Jurgensmeyer Langas, Miguel Moran, Susan Christian, Gregory Webster   +4 more
wiley   +1 more source

Fibulin-4 is essential for maintaining arterial wall integrity in conduit but not muscular arteries [PDF]

, 2017
Homozygous or compound heterozygous mutations in fibulin-4 (FBLN4) lead to autosomal recessive cutis laxa type 1B (ARCL1B), a multisystem disorder characterized by significant cardiovascular abnormalities, including abnormal elastin assembly, arterial ...
Broekelmann, Thomas J, Chu, Mon-Li, Halabi, Carmen M, Lee, Vivian S, Lin, Michelle, Mecham, Robert P   +5 more
core   +3 more sources

Clinical, Echocardiographic, and Socioeconomic Predictors of Progression and Outcomes in Patients With Moderate Aortic Stenosis

Echocardiography, Volume 42, Issue 12, December 2025.
A comprehensive model integrating clinical, imaging, and socioeconomic data improves prediction of disease progression and outcomes in moderate aortic stenosis, supporting a shift toward personalized assessment and management. ABSTRACT Background Despite increased awareness of its clinical consequences, personalized risk stratification in patients with
Alex D'Amico, Paul Nona, Loren Wagner, Miguel R. Sotelo, Chris Rogers, Navin Nanda, Julian Booker, Efstathia Andrikopoulou   +7 more
wiley   +1 more source

Bovine aortic arch with supravalvular aortic stenosis

Indian Heart Journal, 2016
A 5-year-old boy was diagnosed to have supravalvular aortic stenosis (SVAS). On evaluation of CT angiogram, there was associated bovine aortic arch (BAA).
Mohammed Idhrees, Vijay Thomas Cherian, Sabarinath Menon, Thomas Mathew, Baiju S. Dharan, K. Jayakumar   +5 more
doaj   +1 more source

Dissecting Shared Genetic Architecture of Thoracic Aortic Aneurysm and Aortic Related Traits and Identifying SplA/Ryanodine Receptor Domain and SOCS Box Containing 1 Involved in Smooth Muscle Phenotype Switching and Cell Senescence Through Alternative Splicing

The FASEB Journal, Volume 39, Issue 22, 30 November 2025.
The flowchart of the study. BAPN, β‐aminopropionitrile; FUMA, Functional Mapping and Annotation; GO, Gene Ontology; GWAS, genome‐wide association study; KEGG, Kyoto encyclopedia of genes and genomes; LDSC, LD score regression; MR‐JTI, mendelian randomization joint‐tissue imputation; MTAG, multi‐trait analysis of GWAS; siRNA, small interfering RNA ...
Qingyang Song, Tongxin Chu, Quan Liu, Rennan Weng, Huayang Li, Mengya Liang, Zhongkai Wu   +6 more
wiley   +1 more source

Assessment of bicuspid aortic valve phenotypes and associated pathologies: A transesophageal echocardiographic study

Türk Kardiyoloji Derneği Arşivi, 2017
Objective: We investigated the frequency of different bicuspid aortic valve disease (BAV) phenotypes,the associated valvular pathologies, and the aortopathy phenotypes, using 2-dimensional (2D) transthoracic, 2D transesophageal echocardiography (TEE) and
Selcen Yakar Tülüce, Kamil Tülüce, Ersin Çağrı Şimşek, Özgen Şafak, Mehmet Şefa Ökten, Zeynep Yapan Emren, Sadık Volkan Emren, Uğur Kocabaş, Serdar Bayata, Cem Nazlı   +9 more
doaj   +1 more source

Biomarkers of Aortopathy in Marfan Syndrome [PDF]

Cardiology in Review, 2020
Marfan Syndrome (MFS) is an autosomal dominant, genetically inherited connective tissue disorder which primarily affects the cardiovascular system, but can also have systemic manifestations. First described in 1896, MFS has a prevalence of around 1/5000 in the general population. It is becoming increasingly common to see patients with MFS in a clinical
Iskandar, Zaid, Mordi, Ify, Lang, Chim, Huang, Jeffrey, Choy, Anna   +4 more
openaire   +3 more sources