Results 51 to 60 of about 2,749 (160)

Long‐Term Durability of Transcatheter Aortic Valves in Patients With Bicuspid Aortic Stenosis

Catheterization and Cardiovascular Interventions, Volume 106, Issue 3, Page 1746-1757, September 1, 2025.
ABSTRACT Background Data concerning the long‐term durability of transcatheter aortic valves (TAVs) in patients with bicuspid aortic stenosis (AS) are lacking. Aims The study aims to report data on long‐term valve durability following transcatheter aortic valve replacement (TAVR) in bicuspid AS.
Yuheng Jia, Annette Maznyczka, Mauro Boiago, Arif Khokhar, Daijiro Tomii, Antoinette Neylon, Pauline Danthine, Thomas Levesque, Paul Bamford, Stefan Toggweiler, Federico Moccetti, Jarkko Piuhola, Marianna Adamo, Mauro Massussi, Alfonso Ielasi, Matteo Montorfano, Giulia Costa, Martin Swaans, Daniël C. Overduin, Clément Servoz, Caterina Gandolfo, Ingibjörg Jóna Guðmundsdóttir, Stefano Salizzoni, Joanna J. Wykrzykowska, Kees H. van Bergeijk, Andrea Buono, Tau Hartikainen, Stephane Noble, Darren Mylotte, Stephen Brecker, Ahmed Thabit, Antonio Mangieri, Pierfrancesco Agostoni, Matjaž Bunc, Maarten Vanhaverbeke, Johan Bosmans, Hélène Eltchaninoff, Azeem Latib, Daniel Blackman, Nicolas M. Van Mieghem, Yuan Feng, Won‐Keun Kim, Thomas Pilgrim, Bernard Prendergast, Didier Tchétché, Mao Chen, Ole De Backer   +46 more
wiley   +1 more source

Wall Shear Stress Directional Abnormalities in BAV Aortas: Toward a New Hemodynamic Predictor of Aortopathy?

Frontiers in Physiology, 2018
The bicuspid aortic valve (BAV) generates wall shear stress (WSS) abnormalities in the ascending aorta (AA) that may be responsible for the high prevalence of aortopathy in BAV patients.
Janet Liu, Jason A. Shar, Philippe Sucosky   +2 more
doaj   +1 more source

Frequency and Spectrum of Actionable Secondary Findings in the Maltese Population

Molecular Genetics &Genomic Medicine, Volume 13, Issue 9, September 2025.
In a populaiton cohort of 350 individuals, actionable P/LP variants were identified in 12 individuals (3.4%) across autosomal dominant genes. ABSTRACT Background The identification of actionable secondary findings (SFs) through clinical exome sequencing has become increasingly relevant with the integration of genomics into routine healthcare.
Laura Grech, Celine Ann Grech, Jasmine Spiteri, Dillon Mintoff, Nikolai Paul Pace   +4 more
wiley   +1 more source

Society for Maternal‐Fetal Medicine Consult Series #73: Diagnosis and management of right and left heart failure during pregnancy and postpartum

Pregnancy, Volume 1, Issue 5, September 2025.
Abstract Heart failure is a major contributor to maternal morbidity and mortality. Pregnancy is a state of hemodynamic stress, and normal physiologic changes of pregnancy may mimic signs of heart failure. Prepregnancy counseling, multidisciplinary care, and referral to a center with expertise in managing pregnant patients with heart failure can help ...
Society for Maternal‐Fetal Medicine (SMFM), Afshan B. Hameed, Ernesto Licon, Arthur Jason Vaught, Raj Shree, SMFM Publications Committee   +5 more
wiley   +1 more source

Evaluation of relationship between bicuspid aortic valve phenotype with valve dysfunction and associated aortopathy [PDF]

Journal of Cardiovascular and Thoracic Research, 2018
Introduction: Morphology of bicuspid aortic valve (BAV) may have implication in the associated pathologies including aortic stenosis (AS), aortic insufficiency (AI) and aortic dilation.
Mehrnoush Toufan Tabrizi, Roghaieh Rahimi Asl, Soheyla Nazarnia, Leili Pourafkari   +3 more
doaj   +1 more source

Evaluation of 4D Flow MRI‐Derived Aortic Hemodynamics and Their Relationships With Left Ventricular Remodeling in Patients With Moderate Aortic Stenosis: A Preliminary Study

Echocardiography, Volume 42, Issue 9, September 2025.
Patients with moderate AS exhibited various 4D flow MRI‐derived aortic hemodynamic profiles despite having similar mean pressure gradient. Peak turbulent kinetic energy (TKE) significantly correlated with LV volumes, mass, and native T1 value. Our study revealed heterogeneity of aortic hemodynamics and their impact on LV myocardium in patients with ...
Jeong‐Eun Yi, Sungho Park, Osung Kwon, Dongyeop Han, Hyungkyu Huh, Bae Young Lee   +5 more
wiley   +1 more source

Presenilin-1 in smooth muscle cells facilitates hypermuscularization in elastin aortopathy

iScience
Summary: Smooth muscle cell (SMC) accumulation is central to the pathogenesis of elastin-defective arterial diseases, including supravalvular aortic stenosis (SVAS).
Junichi Saito, Jui M. Dave, Freddy Duarte Lau, Daniel M. Greif   +3 more
doaj   +1 more source

Characteristics of Carotid Artery Structure and Mechanical Function and Their Relationships with Aortopathy in Patients with Bicuspid Aortic Valves

Frontiers in Physiology, 2017
Patients with a bicuspid aortic valve (BAV) often have proximal aortic dilatation and systemic vascular dysfunction. We hypothesized that BAV patients would have different carotid artery structural and functional characteristics compared to tricuspid ...
Mihyun Kim, Chi Young Shim, Seong-Chan You, In-Jeong Cho, Geu-Ru Hong, Jong-Won Ha, Namsik Chung   +6 more
doaj   +1 more source

Epidermolysis bullosa for primary care providers: A practical review

Journal of General and Family Medicine, Volume 26, Issue 4, Page 279-291, July 2025.
Abstract Epidermolysis bullosa (EB) is a group of genetic skin diseases, which manifest as fragile skin and blistering in addition to many extracutaneous conditions. Pediatricians and primary care providers play an integral role in managing these patients with multifaceted care needs.
Kennedy Sparling, Judith O'Haver, Muayad Shahin, Amanda Damon, Nichole Halliburton, Kellie Badger, Mariam Iqneibi, Beth Moeves, Harper N. Price, Emily S. Gorell   +9 more
wiley   +1 more source

Loss of wall stress homeostasis in ascending thoracic aortic aneurysm: histomorphometric insights into patient variants

The Journal of Physiology, Volume 603, Issue 14, Page 3899-3922, 15 July 2025.
Abstract figure legend Dynamic interplay between the extracellular matrix (ECM) and vascular smooth muscle cells (VSMCs) in the medial layer of ascending thoracic aortic aneurysms (ATAA) associated with two variants: thickening (hypertrophic) and thinning (hypotrophic) aneurysm remodelling.
Berta H. Ganizada, Koen D. Reesink, Shaiv Parikh, Pepijn J. M. H. Saraber, Jack P. Cleutjens, Austin Isabella, Mathilde Q. E. Krebbekx, Armand M. Jaminon, Cecile F. M. Maassen, Mitch J. F. G. Ramaekers, Bart Spronck, Koen van der Laan, Rory R. Koenen, Roberto Lorusso, Jos G. Maessen, Elham Bidar, Leon J. Schurgers   +16 more
wiley   +1 more source