Results 1 to 10 of about 246,547 (300)
Apathy and impulsivity in frontotemporal lobar degeneration syndromes [PDF]
Brain, 2017 Apathy and impulsivity are common and disabling consequences of frontotemporal lobar degeneration. They cause substantial carer distress, but their aetiology remains elusive.
P Simon Jones +2 more
exaly +5 more sources
Developing a new apathy measurement scale: Dimensional Apathy Scale [PDF]
Psychiatry Research, 2014 Apathy is both a symptom and syndrome prevalent in neurodegenerative disease, including motor system disorders, that affects motivation to display goal directed functions. Levy and Dubois (2006) suggested three apathetic subtypes, Cognitive, Emotional-affective and Auto-activation, all with discrete neural correlates and functional impairments. The aim
Ratko Radakovic
exaly +5 more sources
Apathy in Parkinson’s Disease: Clinical Patterns and Neurobiological Basis
Cells, 2023 Apathy is commonly defined as a loss of motivation leading to a reduction in goal-directed behaviors. This multidimensional syndrome, which includes cognitive, emotional and behavioral components, is one of the most prevalent neuropsychiatric features of
Matthieu Béreau, Vincent Van Waes
exaly +3 more sources
Apathy Is Associated with Slower Gait and Subjective Cognitive Complaints in a South Indian Community-Dwelling Cohort [PDF]
Brain SciencesBackground/Objectives: Apathy is an independent risk factor for dementia and motoric–cognitive risk syndrome (MCR), a predementia syndrome characterized by slow gait and subjective cognitive complaints (SCCs).
Matthew G. Engel +8 more
doaj +2 more sources
Brain Stimulation, 2023 Background: Apathy is reported after subthalamic nucleus deep brain stimulation (STN DBS) and associated with a decreased quality of life in Parkinson's disease (PD) patients.
T.J.C. Zoon +7 more
doaj +1 more source
A data‐driven examination of apathy and depressive symptoms in dementia with independent replication
Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, 2023 Apathy is one of the most common neuropsychiatric symptoms (NPS) and is associated with poor clinical outcomes. Research that helps define the apathy phenotype is urgently needed, particularly for clinical and biomarker studies.
Miguel Vasconcelos Da Silva +6 more
doaj +1 more source
Dimensions of apathy in Parkinson's disease
Brain and Behavior, 2023 Introduction Apathy is one of the most common neuropsychiatric manifestations in Parkinson's disease (PD). Recent proposals consider apathy as a multidimensional construct, which can manifest in behavioral, cognitive, emotional, and/or social dimensions.
Nasya Thompson +4 more
doaj +1 more source
Associations, overlaps and dissociations between apathy and fatigue
Scientific Reports, 2022 Apathy and fatigue have a high prevalence in many pathological populations, but they are also present in healthy adults. The relationship between apathy and fatigue, which are both multidimensional, is still poorly understood. This study aims to describe
Lyne Daumas +6 more
doaj +1 more source
PLoS ONE, 2021 Apathy is defined as reduction of goal-directed behaviors and a common nuisance syndrome of neurodegenerative and psychiatric disease. The underlying mechanism of apathy implicates changes of the front-striatal circuit, but its precise alteration is ...
Chizuko Hamada +5 more
doaj +1 more source
Strategic lesions in the anterior thalamic radiation and apathy in early Alzheimer's disease [PDF]
, 2015 BACKGROUND Behavioural disorders and psychological symptoms of Dementia (BPSD) are commonly observed in Alzheimer's disease (AD), and strongly contribute to increasing patients' disability.
Bozzali, Marco +8 more
core +8 more sources