Results 21 to 30 of about 246,547 (300)

Diagnosis and Assessment of Apathy in Elderly Chinese Patients With Cerebral Small Vessel Disease

Frontiers in Psychiatry, 2021
Objective: The study aimed to estimate the frequency of apathy in Chinese patients with cerebral small vessel disease (CSVD) and investigate the relationship between apathy and neuroimaging markers of CSVD.Methods: A total of 150 CSVD aged patients were ...
Hóngyi Zhào, Hóngyi Zhào, Yu Liu, Zhenxi Xia, Hongyang Xie, Yonghua Huang   +5 more
doaj   +1 more source

Apathy is associated with poor prognosis in Amyotrophic Lateral Sclerosis [PDF]

, 2016
Background: Apathy is the most commonly reported behavioural change in amyotrophic lateral sclerosis (ALS). However, the degree to which it affects prognosis and overlaps with depression in this population is unknown.
Abrahams, Abrahams, Baudic, Berman, Brodaty, Brooks, Cedarbaum, Chio, Chio, Chio, Clarke, Cummings, Elamin, Grossman, Hsieh, Hu, Hu, IBM Corp, Kiernan, Levy, Lillo, Lillo, Lovibond, Marin, McPherson, Mioshi, Mioshi, Mioshi, Murphy, Naismith, Olney, Pluck, Raaphorst, Rippon, Rooney, Strong, Tabachnick, Tsujimoto, Wear, Witgert, Woolley, Woolley   +41 more
core   +1 more source

Lower Choline and Myo-Inositol in Temporo-Parietal Cortex Is Associated With Apathy in Amnestic MCI

Frontiers in Aging Neuroscience, 2018
Apathy is a common symptom in patients with amnestic mild cognitive impairment (aMCI) and is associated with an increased risk of progression to Alzheimer’s disease (AD). The neural substrates underlying apathy in aMCI may involve multiple brain regions,
Shankar Tumati, Shankar Tumati, Esther M. Opmeer, Jan-Bernard C. Marsman, Sander Martens, Fransje E. Reesink, Peter P. De Deyn, Peter P. De Deyn, André Aleman, André Aleman   +9 more
doaj   +1 more source

A Novel Assessment and Profiling of Multidimensional Apathy in Alzheimer's Disease [PDF]

, 2017
BACKGROUND: Apathy is a complex multidimensional syndrome frequently reported in Alzheimer's disease (AD) and is associated with impaired awareness. Here we present a psychometrically robust method to profile apathy in AD.
Aalten, Apostolova, Bayard, Benoit, Biernacki, Bozeat, Brodaty, Brown, Chase, Chow, Clarke, Cronbach, Cummings, Fernandez-Guinea, Fernández-Matarrubia, Fernández-Matarrubia, Folstein, Harrison, Kaufer, Kolanowski, Kumfor, Landes, Law, Lawton, Levy, Levy, Marin, Marin, McPherson, Mioshi, Mograbi, Mortby, Mulin, Palmer, Perry, Quaranta, Radakovic, Radakovic, Radakovic, Radakovic, Raftery, Reichman, Richard, Robert, Robert, Robert, Schwarz, Scrucca, Spalletta, Stanton, Starkstein, Starkstein, Starkstein, Starkstein, Stella, Tagariello, Tangen, van Reekum, Wancata, Yesavage   +59 more
core   +1 more source

Multidimensional apathy: evidence from neurodegenerative disease [PDF]

, 2018
Apathy is a demotivation syndrome common in neurodegenerative diseases and is fundamentally multidimensional in nature. Different methodologies have been used to identify and quantify these dimensions, which has resulted in multifarious concepts, ranging
Abrahams, Sharon, Radakovic, Ratko
core   +2 more sources

Apathy and atrophy of subcortical brain structures in Huntington's disease: A two-year follow-up study

NeuroImage: Clinical, 2018
Background: Huntington's disease (HD) is characterized by motor and behavioral symptoms, and cognitive decline. HD gene carriers and their caregivers report the behavioral and cognitive symptoms as the most burdensome.
Verena Baake, Emma M. Coppen, Erik van Duijn, Eve M. Dumas, Simon J.A. van den Bogaard, Rachael I. Scahill, Hans Johnson, Blair Leavitt, Alexandra Durr, Sarah J. Tabrizi, David Craufurd, Raymund A.C. Roos   +11 more
doaj   +1 more source

Exploring social cognition in patients with apathy following acquired brain damage [PDF]

, 2014
BACKGROUND: Research on cognition in apathy has largely focused on executive functions. To the best of our knowledge, no studies have investigated the relationship between apathy symptoms and processes involved in social cognition.
Glyn W Humphreys, Progress Njomboro, Shoumitro Deb   +2 more
core   +3 more sources

Distinct neuropsychological correlates of cognitive, behavioural and affective apathy sub-domains in acquired brain injury.

Frontiers in Neurology, 2014
Apathy has a high prevalence and a significant contribution to treatment and rehabilitation outcomes in acquired brain damage. Research on the disorder’s neuropsychological correlates has produced mixed results.
Progress eNjomboro, Shoumitro eDeb
doaj   +1 more source

Prevalent, persistent, and impairing: Longitudinal course and impact of apathy in Alzheimer's disease

Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, 2021
Introduction Understanding of the natural history of apathy and its impact on patient function is limited. This study examines, in a large, national sample of Alzheimer's disease (AD) patients with long follow‐ups: (1) prevalence, incidence, and ...
Hillel T. Grossman, Mary Sano, Amy Aloysi, Gregory A. Elder, Judith Neugroschl, Corbett Schimming, Laili Soleimani, Carolyn W. Zhu   +7 more
doaj   +1 more source

Multidimensional apathy and executive dysfunction in amyotrophic lateral sclerosis [PDF]

, 2017
Apathy and cognitive dysfunction are prominent symptoms of Amyotrophic lateral sclerosis (ALS). More specifically ALS patients show increased Initiation apathy-a lack of motivation for self-generation of thoughts as assessed by the Dimensional Apathy ...
Abrahams, Abrahams, Abrahams, Abrahams, Abrahams, Baddeley, Bede, Beeldman, Brown, Caga, Cavallo, Cedarbaum, Cerami, Christopher Crockford, Cuddy, Elamin, Evans, Gibbons, Gillingham, Girardi, Goldstein, Gordon, Grossman, Judith Newton, Laura Stephenson, Levy, Levy, Libon, Lillo, Lulé, Marin, Marin, Marin, Meier, Miyake, Murphy, Niven, Norris, Papps, Pettit, Phukan, Raaphorst, Radakovic, Radakovic, Radakovic, Ratko Radakovic, Robert Swingler, Santangelo, Sedda, Sharon Abrahams, Siddharthan Chandran, Strong, Stuss, Stuss, Stuss, van der Hulst, Wancata, Wechsler, Witgert, Woolley, Yesavage, Young, Zimmerman, Štukovnik   +63 more
core   +2 more sources